LauraMA
@laurama-2023.bsky.social
Reposted by LauraMA
See also the associated paper by Marcelo Torres, Fangping Wan & Cesar de la Fuente-Nunez
@delafuentelab.bsky.social
www.nature.com/articles/s41...
@delafuentelab.bsky.social
www.nature.com/articles/s41...
Deep learning reveals antibiotics in the archaeal proteome - Nature Microbiology
Use of artificial intelligence to mine proteomes of archaea led to the discovery of archaeasins, antimicrobials that kill drug-resistant bacteria in laboratory and animal models, offering a promising source of future antibiotics.
www.nature.com
September 23, 2025 at 12:29 PM
See also the associated paper by Marcelo Torres, Fangping Wan & Cesar de la Fuente-Nunez
@delafuentelab.bsky.social
www.nature.com/articles/s41...
@delafuentelab.bsky.social
www.nature.com/articles/s41...
Reposted by LauraMA
Bacteria with archaella, who would have thought that this existed. Happy to share that it does 🎉and we just published it today in @natmicrobiol.nature.com 🎉🥳. Congrats to everyone involved! 🦠
Happy to share that our story on the bacterial archaellum was published today in @natmicrobiol.nature.com
www.nature.com/articles/s41...
Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social
www.nature.com/articles/s41...
Congrats to the authors: @sshamphavi.bsky.social @loumollat.bsky.social @mariejoest.bsky.social Najwa Taib and @sgribaldo.bsky.social
September 17, 2025 at 5:50 PM
Bacteria with archaella, who would have thought that this existed. Happy to share that it does 🎉and we just published it today in @natmicrobiol.nature.com 🎉🥳. Congrats to everyone involved! 🦠
Reposted by LauraMA
Manuscript/resource alert #microsky 🦠 My lab offers the community a collection of 30 E. coli (CloneFISH) cultures, each carrying a plasmid for the heterologous expression of a (near) full-length 16S rRNA gene from one of 30 lineages of archaea, including 19 yet uncultured ones.
June 24, 2025 at 1:53 PM
Manuscript/resource alert #microsky 🦠 My lab offers the community a collection of 30 E. coli (CloneFISH) cultures, each carrying a plasmid for the heterologous expression of a (near) full-length 16S rRNA gene from one of 30 lineages of archaea, including 19 yet uncultured ones.
Reposted by LauraMA
Joining the race to the bottom has never been cooler...
www.biorxiv.org/node/4580343...
www.biorxiv.org/content/10.1...
www.biorxiv.org/node/4580343...
www.biorxiv.org/content/10.1...
A cellular entity retaining only its replicative core: Hidden archaeal lineage with an ultra-reduced genome
Defining the minimal genetic requirements for cellular life remains a fundamental question in biology. Genomic exploration continually reveals novel microbial lineages, often exhibiting extreme genome...
www.biorxiv.org
May 25, 2025 at 2:48 PM
Joining the race to the bottom has never been cooler...
www.biorxiv.org/node/4580343...
www.biorxiv.org/content/10.1...
www.biorxiv.org/node/4580343...
www.biorxiv.org/content/10.1...
Reposted by LauraMA
The Archaeacast! Yes, a podcast about #archaea!
by Priyanka Chatterjee, @cjhines.bsky.social, Alex Phillips, Theopi Rados & guests!
Sixth episode: Archaea and Us: Heroes or Villains?
rss.com/podcasts/arc...
@archaeapowerhour.bsky.social @archaeabio.bsky.social
#microsky
by Priyanka Chatterjee, @cjhines.bsky.social, Alex Phillips, Theopi Rados & guests!
Sixth episode: Archaea and Us: Heroes or Villains?
rss.com/podcasts/arc...
@archaeapowerhour.bsky.social @archaeabio.bsky.social
#microsky
May 21, 2025 at 9:14 PM
The Archaeacast! Yes, a podcast about #archaea!
by Priyanka Chatterjee, @cjhines.bsky.social, Alex Phillips, Theopi Rados & guests!
Sixth episode: Archaea and Us: Heroes or Villains?
rss.com/podcasts/arc...
@archaeapowerhour.bsky.social @archaeabio.bsky.social
#microsky
by Priyanka Chatterjee, @cjhines.bsky.social, Alex Phillips, Theopi Rados & guests!
Sixth episode: Archaea and Us: Heroes or Villains?
rss.com/podcasts/arc...
@archaeapowerhour.bsky.social @archaeabio.bsky.social
#microsky
Reposted by LauraMA
1/ Excited to share our latest work on gene transfer agents (GTAs) in Caulobacter crescentus, led by Emma Banks in collaboration with Pavol Bardy and Mai Nguyen from York!!! See a brief thread below.
shorturl.at/o6S1w
shorturl.at/o6S1w
A bacterial CARD-NLR immune system controls the release of gene transfer agents
Bacteria have evolved a wide array of immune systems to detect and defend against external threats including mobile genetic elements (MGEs) such as bacteriophages, plasmids, and transposons. MGEs are ...
shorturl.at
May 9, 2025 at 8:08 AM
1/ Excited to share our latest work on gene transfer agents (GTAs) in Caulobacter crescentus, led by Emma Banks in collaboration with Pavol Bardy and Mai Nguyen from York!!! See a brief thread below.
shorturl.at/o6S1w
shorturl.at/o6S1w
Our new paper on archaeal anti-CRISPRs is out in
@Nature (@SpringerNature)! 🔗 rdcu.be/eh1Ma
Using a native virus–host model (SIRV2–S. islandicus), we show that overexpression in foreign hosts can lead to false positives.
🧵(1/n) #CRISPR #archaea #antiCRISPR #virology
@Nature (@SpringerNature)! 🔗 rdcu.be/eh1Ma
Using a native virus–host model (SIRV2–S. islandicus), we show that overexpression in foreign hosts can lead to false positives.
🧵(1/n) #CRISPR #archaea #antiCRISPR #virology
Natively expressed AcrIII-1 does not function as an anti-CRISPR protein
Nature - Natively expressed AcrIII-1 does not function as an anti-CRISPR protein
rdcu.be
April 18, 2025 at 2:50 PM
Our new paper on archaeal anti-CRISPRs is out in
@Nature (@SpringerNature)! 🔗 rdcu.be/eh1Ma
Using a native virus–host model (SIRV2–S. islandicus), we show that overexpression in foreign hosts can lead to false positives.
🧵(1/n) #CRISPR #archaea #antiCRISPR #virology
@Nature (@SpringerNature)! 🔗 rdcu.be/eh1Ma
Using a native virus–host model (SIRV2–S. islandicus), we show that overexpression in foreign hosts can lead to false positives.
🧵(1/n) #CRISPR #archaea #antiCRISPR #virology
Reposted by LauraMA
♀️🇲🇽🧪🦠 This paper about the challenges of being a female microbiologist in México is authored by four women central to my career:
my PhD supervisor Valeria Souza
my PhD committee member Gabriela Olmedo
my PhD colleagues Esmeralda Lopez and Ana Escalante
doi.org/10.1016/j.ti...
my PhD supervisor Valeria Souza
my PhD committee member Gabriela Olmedo
my PhD colleagues Esmeralda Lopez and Ana Escalante
doi.org/10.1016/j.ti...
December 15, 2024 at 3:13 PM
♀️🇲🇽🧪🦠 This paper about the challenges of being a female microbiologist in México is authored by four women central to my career:
my PhD supervisor Valeria Souza
my PhD committee member Gabriela Olmedo
my PhD colleagues Esmeralda Lopez and Ana Escalante
doi.org/10.1016/j.ti...
my PhD supervisor Valeria Souza
my PhD committee member Gabriela Olmedo
my PhD colleagues Esmeralda Lopez and Ana Escalante
doi.org/10.1016/j.ti...
Reposted by LauraMA
New paper! We analyzed gut #microbiomes of 250+ individuals (ages 19–109).
#Centenarians often show a high-methanogen “human cow” phenotype 🐄, with #Methanobrevibacter smithii dominance and youth-like archaeal profiles. #Archaea may stabilize networks in aging.
Link: rdcu.be/egk03
@archaeasky
#Centenarians often show a high-methanogen “human cow” phenotype 🐄, with #Methanobrevibacter smithii dominance and youth-like archaeal profiles. #Archaea may stabilize networks in aging.
Link: rdcu.be/egk03
@archaeasky
Age-related dynamics of predominant methanogenic archaea in the human gut microbiome
rdcu.be
April 4, 2025 at 6:11 AM
New paper! We analyzed gut #microbiomes of 250+ individuals (ages 19–109).
#Centenarians often show a high-methanogen “human cow” phenotype 🐄, with #Methanobrevibacter smithii dominance and youth-like archaeal profiles. #Archaea may stabilize networks in aging.
Link: rdcu.be/egk03
@archaeasky
#Centenarians often show a high-methanogen “human cow” phenotype 🐄, with #Methanobrevibacter smithii dominance and youth-like archaeal profiles. #Archaea may stabilize networks in aging.
Link: rdcu.be/egk03
@archaeasky
Reposted by LauraMA
#weekendreading🔬📑
Tissue-like multicellular development triggered by mechanical compression in archaea
@science.org #microsky
www.science.org/doi/10.1126/...
Tissue-like multicellular development triggered by mechanical compression in archaea
@science.org #microsky
www.science.org/doi/10.1126/...
Tissue-like multicellular development triggered by mechanical compression in archaea
The advent of clonal multicellularity is a critical evolutionary milestone, seen often in eukaryotes, rarely in bacteria, and only once in archaea. We show that uniaxial compression induces clonal mul...
www.science.org
April 4, 2025 at 3:46 PM
#weekendreading🔬📑
Tissue-like multicellular development triggered by mechanical compression in archaea
@science.org #microsky
www.science.org/doi/10.1126/...
Tissue-like multicellular development triggered by mechanical compression in archaea
@science.org #microsky
www.science.org/doi/10.1126/...
Reposted by LauraMA
From the @commsbio.bsky.social journal | Advancing archaeal research through FAIR resource and data sharing, and inclusive community building | #Bioinformatics #FAIR #OpenScience
#OpenAccess #OpenData 🧬 🖥️ 🧪 🔓
⬇️
www.nature.com/articles/s42...
#OpenAccess #OpenData 🧬 🖥️ 🧪 🔓
⬇️
www.nature.com/articles/s42...
Advancing archaeal research through FAIR resource and data sharing, and inclusive community building - Communications Biology
Archaeal research and its growing importance have benefited from a community that is engaged in various collaborative efforts, which are highlighted here with examples for the sharing of resources and...
www.nature.com
March 31, 2025 at 3:38 PM
From the @commsbio.bsky.social journal | Advancing archaeal research through FAIR resource and data sharing, and inclusive community building | #Bioinformatics #FAIR #OpenScience
#OpenAccess #OpenData 🧬 🖥️ 🧪 🔓
⬇️
www.nature.com/articles/s42...
#OpenAccess #OpenData 🧬 🖥️ 🧪 🔓
⬇️
www.nature.com/articles/s42...
Reposted by LauraMA
Open PhD position! Do you want to work with the human #archaeome and understand the potential effect on the #immune system? Please check the call, including another exciting opening of @cdiener.com on #microbiome research www.medunigraz.at/doktoratsstu... #microbiomesky #archaeasky #microsky
PhD Application and Admission
www.medunigraz.at
February 13, 2025 at 9:08 AM
Open PhD position! Do you want to work with the human #archaeome and understand the potential effect on the #immune system? Please check the call, including another exciting opening of @cdiener.com on #microbiome research www.medunigraz.at/doktoratsstu... #microbiomesky #archaeasky #microsky
Reposted by LauraMA
New preprint from our lab!
Story started long ago that took many years in the making.
Great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social groups.
Generously funded by BBSRC @ukri.org & @leverhulme.bsky.social
How do #archaea segregate their chromosome?
#microsky #archaeasky
Story started long ago that took many years in the making.
Great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social groups.
Generously funded by BBSRC @ukri.org & @leverhulme.bsky.social
How do #archaea segregate their chromosome?
#microsky #archaeasky
Coupling chromosome organization to genome segregation in Archaea https://www.biorxiv.org/content/10.1101/2025.02.07.637068v1
February 9, 2025 at 10:51 AM
New preprint from our lab!
Story started long ago that took many years in the making.
Great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social groups.
Generously funded by BBSRC @ukri.org & @leverhulme.bsky.social
How do #archaea segregate their chromosome?
#microsky #archaeasky
Story started long ago that took many years in the making.
Great collaboration with @archaellum.bsky.social & @tunglejic.bsky.social groups.
Generously funded by BBSRC @ukri.org & @leverhulme.bsky.social
How do #archaea segregate their chromosome?
#microsky #archaeasky
Reposted by LauraMA
A new year, a new social network and a new article in @naturecomms.bsky.social ! It unveils how archaeal RPA orchestrates the recruitment of key players in 🧬 replication primase and polD through its WH domain, with structures of both complexes!!
rdcu.be/d6GAY
rdcu.be/d6GAY
Communication between DNA polymerases and Replication Protein A within the archaeal replisome
Nature Communications - The single stranded DNA binding protein RPA plays a pivotal role in DNA replication. The archaeal RPA hosts a WH domain that interacts with the DNA primase and the...
rdcu.be
January 18, 2025 at 6:30 AM
A new year, a new social network and a new article in @naturecomms.bsky.social ! It unveils how archaeal RPA orchestrates the recruitment of key players in 🧬 replication primase and polD through its WH domain, with structures of both complexes!!
rdcu.be/d6GAY
rdcu.be/d6GAY