@labwyllie.bsky.social
Delighted our latest paper is now published in Science Translational Medicine. Fantastic collab with Dr Avninder Bhambra and his team. Our studies reveal promising quinazolines selectively target KRS in T. cruzi. www.science.org/doi/10.1126/...
@dundee.ac.uk
@dundee.ac.uk
Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease
Quinazolines targeting Trypanosoma cruzi lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease.
www.science.org
July 9, 2025 at 7:06 PM
Delighted our latest paper is now published in Science Translational Medicine. Fantastic collab with Dr Avninder Bhambra and his team. Our studies reveal promising quinazolines selectively target KRS in T. cruzi. www.science.org/doi/10.1126/...
@dundee.ac.uk
@dundee.ac.uk
Fantastic paper from MoA group alumni Richard Wall and colleagues 🙌 www.nature.com/articles/s41...
Targeting de novo purine biosynthesis for tuberculosis treatment - Nature
The validation of inhibitors targeting PurF, a novel drug target for tuberculosis drug discovery, is described.
www.nature.com
June 18, 2025 at 4:13 PM
Fantastic paper from MoA group alumni Richard Wall and colleagues 🙌 www.nature.com/articles/s41...
New paper alert! Enjoy!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
The Thienopyrimidinone Gamhépathiopine Targets the QO Site of Plasmodium falciparum Cytochrome b
Chemotherapy remains a key component of the arsenal of tools to fight malaria. Specifically, new drugs with diverse mechanism(s) of action are required to combat existing drug resistance. Here, we des...
pubs.acs.org
June 11, 2025 at 4:53 PM
New paper alert! Enjoy!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Hello Blue-sky! Delighted to be on an inclusive and well run platform!
April 3, 2025 at 7:07 PM
Hello Blue-sky! Delighted to be on an inclusive and well run platform!