IMAGE Lab
@labphan.bsky.social
B cells | Macrophages | Immunity | Autoimmunity | Cancer | Osteoclasts | Osteomorphs | Intravital imaging | Precision Immunology
Rama used intravital microscopy to show that Bmems were positioned deeper in follicle ndLN vs dLN where they were largely confined to the SCS layer. Depletion of CD169+ SCS macrophages (SSMs) with blocking anti-CSF1R mAb led to relocalisation of dLN Bmems deeper in the follicle.
April 29, 2025 at 1:20 PM
Rama used intravital microscopy to show that Bmems were positioned deeper in follicle ndLN vs dLN where they were largely confined to the SCS layer. Depletion of CD169+ SCS macrophages (SSMs) with blocking anti-CSF1R mAb led to relocalisation of dLN Bmems deeper in the follicle.