Eran Perlson
@labperlson.bsky.social
Professor, Head of the Laboratory of Molecular and Cellular Mechanisms of Neurodegenerative Diseases, Axonal Transport and Local Synthesis, NMJ
Reposted by Eran Perlson
Online now at @cp-cell.bsky.social , the culmination of a 12-year effort. 🧵 to follow later this evening
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Repeat-element RNAs integrate a neuronal growth circuit
SINEs of recovery: A subset of small RNAs encoded by repetitive genomic elements are
induced by nerve lesion to regulate protein synthesis and enhance axonal growth.
www.cell.com
May 16, 2025 at 3:20 PM
Online now at @cp-cell.bsky.social , the culmination of a 12-year effort. 🧵 to follow later this evening
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Reposted by Eran Perlson
A 🧵 to walk those interested through this paper...
Online now at @cp-cell.bsky.social , the culmination of a 12-year effort. 🧵 to follow later this evening
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
Repeat-element RNAs integrate a neuronal growth circuit
SINEs of recovery: A subset of small RNAs encoded by repetitive genomic elements are
induced by nerve lesion to regulate protein synthesis and enhance axonal growth.
www.cell.com
May 16, 2025 at 4:50 PM
A 🧵 to walk those interested through this paper...
Reposted by Eran Perlson
This powerful and unbiased way to identify links between genetic variants and biological traits has changed scientists’ understanding of complex diseases and how to treat them
https://go.nature.com/3RPTMTG
https://go.nature.com/3RPTMTG
Twenty years of genome-wide association studies
The first robust association between a genetic variant and disease risk.
go.nature.com
April 15, 2025 at 4:58 PM
This powerful and unbiased way to identify links between genetic variants and biological traits has changed scientists’ understanding of complex diseases and how to treat them
https://go.nature.com/3RPTMTG
https://go.nature.com/3RPTMTG
Reposted by Eran Perlson
Happy to share our new study that was just published in Neuron! www.cell.com/neuron/fullt...
Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures
TDP-43 pathology characterizes neurodegenerative diseases. Scialò et al. use in vitro-generated
and patient-derived TDP-43 aggregates as seeds to show that seed-induced TDP-43 cytoplasmic
aggregation ...
www.cell.com
March 28, 2025 at 3:15 PM
Happy to share our new study that was just published in Neuron! www.cell.com/neuron/fullt...
Reposted by Eran Perlson
MicroRNAs alteration and unique distribution in the soma and synapses of substantia nigra in Parkinsons disease https://www.biorxiv.org/content/10.1101/2025.03.12.642888v1
March 14, 2025 at 2:15 AM
MicroRNAs alteration and unique distribution in the soma and synapses of substantia nigra in Parkinsons disease https://www.biorxiv.org/content/10.1101/2025.03.12.642888v1
Reposted by Eran Perlson
Perspective, led by Martin, on the current application and future potential for blood neurofilament light chain level in neurological disorders, including #ALS pubmed.ncbi.nlm.nih.gov/39845125/
Blood level of neurofilament light chain as a biomarker for neurological disorders - PubMed
Blood level of neurofilament light chain as a biomarker for neurological disorders
pubmed.ncbi.nlm.nih.gov
January 29, 2025 at 10:14 AM
Perspective, led by Martin, on the current application and future potential for blood neurofilament light chain level in neurological disorders, including #ALS pubmed.ncbi.nlm.nih.gov/39845125/