Kevin Bonham
@kevinbonham.com
Assistant Professor at Tufts Medicine studying microbes, brains, and the immune system 🚽🦠🧠
Fermenter, gardener, Zen Buddhist. Ask me about #julialang!
🎙️: https://audiommunity.org
🌎: https://blog.bonham.ch
💻: https://GitHub.com/kescobo
Fermenter, gardener, Zen Buddhist. Ask me about #julialang!
🎙️: https://audiommunity.org
🌎: https://blog.bonham.ch
💻: https://GitHub.com/kescobo
September 21, 2025 at 2:36 AM
~5-6 inch long mantis hanging out on some nearly blooming sedum 🌱
August 26, 2025 at 1:17 PM
~5-6 inch long mantis hanging out on some nearly blooming sedum 🌱
But amazingly, when we looked longitudinally (microbiome at an early visit associated with VEP measured at a later visit) we saw WAY more associations.
This isn't direct evidence of a causal interaction, but the reverse was NOT true - early VEP was not associated with later microbiome much.
12/x
This isn't direct evidence of a causal interaction, but the reverse was NOT true - early VEP was not associated with later microbiome much.
12/x
July 2, 2025 at 4:48 PM
But amazingly, when we looked longitudinally (microbiome at an early visit associated with VEP measured at a later visit) we saw WAY more associations.
This isn't direct evidence of a causal interaction, but the reverse was NOT true - early VEP was not associated with later microbiome much.
12/x
This isn't direct evidence of a causal interaction, but the reverse was NOT true - early VEP was not associated with later microbiome much.
12/x
We then used a technique called "Feature Set Enrichment Analysis" to assess the relationship between microbial neuroactive genes and the VEP. We saw some associations when we looked at VEP measured at the same visit as the microbiome...
🧵 11/x
🧵 11/x
July 2, 2025 at 4:48 PM
We then used a technique called "Feature Set Enrichment Analysis" to assess the relationship between microbial neuroactive genes and the VEP. We saw some associations when we looked at VEP measured at the same visit as the microbiome...
🧵 11/x
🧵 11/x
VEP can be accurately assessed even in newborns. It measures a characteristic response in the visual cortex - we can use the amplitude and latency of each of the 3 characteristic peaks as readouts of brain activity structure (specifically myelination) respectively
🧵 10/x
🧵 10/x
July 2, 2025 at 4:48 PM
VEP can be accurately assessed even in newborns. It measures a characteristic response in the visual cortex - we can use the amplitude and latency of each of the 3 characteristic peaks as readouts of brain activity structure (specifically myelination) respectively
🧵 10/x
🧵 10/x
In the present work, we had a cohort of nearly 200 kids, most of which had at least 2, and often 3 study visits in the first 14 months of life, where we collected stool samples and / or measured their brain activity using an EEG-based technique called Visual Evoked Potential (VEP)
🧵 9/x
🧵 9/x
July 2, 2025 at 4:48 PM
In the present work, we had a cohort of nearly 200 kids, most of which had at least 2, and often 3 study visits in the first 14 months of life, where we collected stool samples and / or measured their brain activity using an EEG-based technique called Visual Evoked Potential (VEP)
🧵 9/x
🧵 9/x
🎉 New paper alert, and it's an editor's pick! Looking at the gut #microbiome #brain axis in infants using metagenomics and EEG 🧪🦠
with @emma-margolis.bsky.social, @laurelgd.bsky.social, @gfahurbottino.bsky.social, done in @mightycrobe.bsky.social 's lab.
journals.asm.org/doi/10.1128/...
🧵 1/x
with @emma-margolis.bsky.social, @laurelgd.bsky.social, @gfahurbottino.bsky.social, done in @mightycrobe.bsky.social 's lab.
journals.asm.org/doi/10.1128/...
🧵 1/x
July 2, 2025 at 4:48 PM
🎉 New paper alert, and it's an editor's pick! Looking at the gut #microbiome #brain axis in infants using metagenomics and EEG 🧪🦠
with @emma-margolis.bsky.social, @laurelgd.bsky.social, @gfahurbottino.bsky.social, done in @mightycrobe.bsky.social 's lab.
journals.asm.org/doi/10.1128/...
🧵 1/x
with @emma-margolis.bsky.social, @laurelgd.bsky.social, @gfahurbottino.bsky.social, done in @mightycrobe.bsky.social 's lab.
journals.asm.org/doi/10.1128/...
🧵 1/x
@jvl.bsky.social I am normally at least open to your "let the voters have what they asked for" theory, but not on vaccines.
We're on the inflection point for measles vaccination, and screwing up means kids are going to die
jamanetwork.com/journals/jam...
We're on the inflection point for measles vaccination, and screwing up means kids are going to die
jamanetwork.com/journals/jam...
June 12, 2025 at 2:16 AM
@jvl.bsky.social I am normally at least open to your "let the voters have what they asked for" theory, but not on vaccines.
We're on the inflection point for measles vaccination, and screwing up means kids are going to die
jamanetwork.com/journals/jam...
We're on the inflection point for measles vaccination, and screwing up means kids are going to die
jamanetwork.com/journals/jam...
Well, free will *is* an illusion, but given the context I don't think that's it
May 9, 2025 at 2:04 AM
Well, free will *is* an illusion, but given the context I don't think that's it
Silver lining, they at least acknowledge evolution 😓🧪https://grants.nih.gov/policy-and-compliance/implementation-of-new-initiatives-and-policies/nih-grants-and-funding-information-status
March 25, 2025 at 10:25 PM
Silver lining, they at least acknowledge evolution 😓🧪https://grants.nih.gov/policy-and-compliance/implementation-of-new-initiatives-and-policies/nih-grants-and-funding-information-status
March 7, 2025 at 5:37 PM
A more #Boston protest sign never was #standupforscience2025
March 7, 2025 at 5:24 PM
A more #Boston protest sign never was #standupforscience2025
I was sure "obtunded" was a typo - learned something new today!
February 18, 2025 at 5:08 PM
I was sure "obtunded" was a typo - learned something new today!
Civil society stepping up to preserve our #data in the face of authoritarians trying to pull it down #statistics
apdu.org?p=5812583
www.populationassociation.org/blogs/paa-we...
apdu.org?p=5812583
www.populationassociation.org/blogs/paa-we...
February 3, 2025 at 9:37 PM
Civil society stepping up to preserve our #data in the face of authoritarians trying to pull it down #statistics
apdu.org?p=5812583
www.populationassociation.org/blogs/paa-we...
apdu.org?p=5812583
www.populationassociation.org/blogs/paa-we...
Didn't know who "this dude" is but looks like I gave up earlier.
Love this feature of bsky
Love this feature of bsky
January 19, 2025 at 11:20 PM
Didn't know who "this dude" is but looks like I gave up earlier.
Love this feature of bsky
Love this feature of bsky
Again, take a look at this from Feynman and tell me, did he not understand the material enough to make it easy to understand?
December 28, 2024 at 6:37 PM
Again, take a look at this from Feynman and tell me, did he not understand the material enough to make it easy to understand?
And since you're so enamored of Feynman, here's a clear-as-mud description from the second paragraph of a book of his lectures. Oh, the oscillators are merely quantum? 🤪
And what are the energies? Oh an equation with Greek symbols? Yeah, perfectly understandable to a lay person
And what are the energies? Oh an equation with Greek symbols? Yeah, perfectly understandable to a lay person
December 28, 2024 at 2:51 PM
And since you're so enamored of Feynman, here's a clear-as-mud description from the second paragraph of a book of his lectures. Oh, the oscillators are merely quantum? 🤪
And what are the energies? Oh an equation with Greek symbols? Yeah, perfectly understandable to a lay person
And what are the energies? Oh an equation with Greek symbols? Yeah, perfectly understandable to a lay person
Traditional German pfeffernüsse - I've been wanting to make these myself for ages, finally was able to thanks to the lebkuchengewürz my mom brought back from Switzerland 😋
December 24, 2024 at 9:06 PM
Traditional German pfeffernüsse - I've been wanting to make these myself for ages, finally was able to thanks to the lebkuchengewürz my mom brought back from Switzerland 😋
Saw this and immediately thought of @cmolanphy.bsky.social - have you done a Hit Parade on collaborations?
The Marketing Hurricane of ‘Wicked’ Says a Lot About Our Culture www.nytimes.com/2024/12/14/o...
The Marketing Hurricane of ‘Wicked’ Says a Lot About Our Culture www.nytimes.com/2024/12/14/o...
December 15, 2024 at 9:51 PM
Saw this and immediately thought of @cmolanphy.bsky.social - have you done a Hit Parade on collaborations?
The Marketing Hurricane of ‘Wicked’ Says a Lot About Our Culture www.nytimes.com/2024/12/14/o...
The Marketing Hurricane of ‘Wicked’ Says a Lot About Our Culture www.nytimes.com/2024/12/14/o...
Interesting, just tried it on Firefox Mobile and it looks fine. Chrome and Vivaldi (chromium-based) both have the issue. This is on android 🤷
November 30, 2024 at 2:55 PM
Interesting, just tried it on Firefox Mobile and it looks fine. Chrome and Vivaldi (chromium-based) both have the issue. This is on android 🤷
Thanks for this! I'm curious - is the inclusion of LaTeX code intentional or a weird rendering artifact? It doesn't seem to happen for the inline stuff.
This is on Mobile (through the browser, not app)
This is on Mobile (through the browser, not app)
November 30, 2024 at 11:38 AM
Thanks for this! I'm curious - is the inclusion of LaTeX code intentional or a weird rendering artifact? It doesn't seem to happen for the inline stuff.
This is on Mobile (through the browser, not app)
This is on Mobile (through the browser, not app)
One thing that no one tells you about fatherhood is that sometimes you go to wash your hands after using the bathroom and are reminded by the mirror that you have a parasaurolophus sticker in the center of your forehead
November 29, 2024 at 12:48 AM
One thing that no one tells you about fatherhood is that sometimes you go to wash your hands after using the bathroom and are reminded by the mirror that you have a parasaurolophus sticker in the center of your forehead