Professor Stephan Züchner presented his fascinating work on the genomic spectrum of repeat expansion loci and their growing associations with disease 🧠
Professor Stephan Züchner presented his fascinating work on the genomic spectrum of repeat expansion loci and their growing associations with disease 🧠
Some of his key findings include:
• GRN LOF→ microglial overactivation and lysosomal failure
• Lysosomal failure → microglial degeneration eventually worsening neuropathology
Some of his key findings include:
• GRN LOF→ microglial overactivation and lysosomal failure
• Lysosomal failure → microglial degeneration eventually worsening neuropathology