Joseph Lemaitre
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josephlemaitre.bsky.social
Joseph Lemaitre
@josephlemaitre.bsky.social
👀 Developing novel infectious disease dynamics modeling approaches to inform public health policies
📍Assistant Professor at UNC-Chapel Hill (🇺🇸), PhD from EPFL (🇨🇭).
🌍 josephlemaitre.com
Inconsistent is what I dislike the most
October 22, 2025 at 12:23 PM
last time I tried it the system library autocomplete was super slow... not sure if I had a poor config, but I'd say half a second to get the proposal. I was really neat though
August 19, 2025 at 7:38 PM
Great read.
If priced out of a bet, the best things is to sell the opportunity to bet to a higher bankroll party (if possible).
There are many cases in life where uncertainty can be traded at discount for certainty (insurance policy is a bet on a home getting flooded, bank loans, ...)
July 24, 2025 at 6:15 AM
Oh make sense
July 17, 2025 at 10:47 PM
I don’t know R but these things are not plain text files?
July 17, 2025 at 8:00 PM
Does Lucy get a nametag ?
July 14, 2025 at 1:23 PM
This project is supported by the Swiss National Science Foundation @snsf.ch, on a project grant specifically written for this reproducibility project! It’s a great win 🎉
July 11, 2025 at 9:26 AM
.. but found Aider (usually Sonnet Architect + DeepSeek implementor) and Claude Code extremely productive.
Task is also important, it is incredible and safe for plotting and front-end... found it slows me down on many pure modeling task. All anecdotal obviously.
July 10, 2025 at 9:28 PM
yes, very nice someone studied it so well. I am very curious on their hinted follow-up on agent. I always fount LLM clunky, and cursor frustrating (there is some kind of bad context compression or something) ...
July 10, 2025 at 9:28 PM
Reposted by Joseph Lemaitre
But in fact, fly immunity is highly reproducible! 🎊

~80% of claims could be verified. Moreover, some challenged claims just reflect the field advancing its knowledge/tools.

The lesson: if the tools are good and the research largely exempt from direct translation pressures, science works.

3.5/n
July 10, 2025 at 8:23 AM
Reposted by Joseph Lemaitre
When everything is considered together (w/ caveats), the most prestigious institutes are the most likely to produce irreproducible work. Journal tier was a more minor effect, and in fact, "high-impact" but not "trophy" journals publish the most reproducible science.

But, many caveats (cont.)

4.3/n
July 10, 2025 at 8:23 AM
Reposted by Joseph Lemaitre
more than that but right order of magnitude. I always say $10^1 for preprint; $10^3 for journal article; $10^5 for research. most costs are staff not tech because of responsible screening, customer service, etc.
July 2, 2025 at 6:20 PM
Seems like it cannot do these little neat interactive javascript diagrams but claude has gotten better at ascii
July 1, 2025 at 2:34 PM
I remember you talking about this :D This is great (I get a Error though, only when I am logged with Claude).
Hope you get back the you get a list of the questions
July 1, 2025 at 2:29 PM
I'm not in epiengage but I'll try with something more unformed ! Squares with LLMs ability in green field projects vs already existing stuff.
June 30, 2025 at 2:30 PM
Oh no, I now have to test twice the hypothesis 😦
June 30, 2025 at 2:13 PM
interesting, somehow never managed to use LLM for this, they always compromise my ideas/go too far.... I find them useful for nearly everything else (finding flaws in ideas, developing the concept).

Perhaps my notes are too scattered. Or my prompt is bad.
June 30, 2025 at 2:01 PM
(Obvious disclaimer that LLM use comes with many shortcomings, and world model is something that is hard to define. Just hope for more nuance.)

arxiv.org/pdf/2403.154... is also a good read (yay for independent researchers).
arxiv.org
June 30, 2025 at 11:12 AM
Obviously, this last bit also highlights that the world-model is relatively brittle. But still, it exists.

That's for non-coders. For coders, there is a before and after using Claude Code. A lot of the academic literature on LLMs brushes over code (like the big PNAS piece recently forgot who).
June 30, 2025 at 11:12 AM
Chess is even my pet example to demonstrate how world-models are built by Transformers + Data.
The proportion of legal moves is very low, and a LLM always plays legal moves and quite good ones.

Gary's claim is caused by the chat environment that destroys the context windows for chess-playing.
June 30, 2025 at 11:12 AM