Joe Lannan
josephlannan.bsky.social
Joe Lannan
@josephlannan.bsky.social
Researcher in biophysics
Reposted by Joe Lannan
🧪 Punchline of our most recent preprint about how a giant single cell changes shape super fast, check the thread for more info!
Overall, we hypothesize a multi-scale model that can explain Spirostomum contraction from the molecular (nanometer) to the organismal (millimeter) scale.

Not only is this mechanism unusual (and plain cool!), it gives us a new blueprint to control or even synthetically actuate contractility. 12/13
November 16, 2024 at 9:38 PM
Reposted by Joe Lannan
New pre-print on ultrafast contracting cells. See thread below
Very excited to share a thread about our new preprint! It's a highly collaborative project, w key contributions from @josephlannan.bsky.social (in my lab) @bhamlalab.bsky.social (+ GS Luke Xu), Dinner Lab (+ PD Cal Floyd), Jerry Honts, Marshall lab (+ GS Connie Yan), and Suri Vaikuntanathan 1/13
Fishnet mesh of centrin-Sfi1 drives ultrafast calcium-activated contraction of the giant cell Spirostomum ambiguum https://www.biorxiv.org/content/10.1101/2024.11.07.622534v1
November 17, 2024 at 6:17 PM
Reposted by Joe Lannan
Very excited to share a thread about our new preprint! It's a highly collaborative project, w key contributions from @josephlannan.bsky.social (in my lab) @bhamlalab.bsky.social (+ GS Luke Xu), Dinner Lab (+ PD Cal Floyd), Jerry Honts, Marshall lab (+ GS Connie Yan), and Suri Vaikuntanathan 1/13
November 15, 2024 at 2:53 PM
Reposted by Joe Lannan
Fishnet mesh of centrin-Sfi1 drives ultrafast calcium-activated contraction of the giant cell Spirostomum ambiguum https://www.biorxiv.org/content/10.1101/2024.11.07.622534v1
Fishnet mesh of centrin-Sfi1 drives ultrafast calcium-activated contraction of the giant cell Spirostomum ambiguum https://www.biorxiv.org/content/10.1101/2024.11.07.622534v1
Spirostomum is a unicellular ciliate capable of contracting to a quarter of its body length in less
www.biorxiv.org
November 8, 2024 at 4:30 PM