Jorge Almagro
@jorgealmagro.bsky.social
LSRF postdoctoral fellow at @thefuchslab.bsky.social, Rockefeller Uni 🗽 | Cancer biology 🦀 | Birds 🦩 | Progressivism & Union Power ✊🏼 | Free Palestine 🇵🇸 | He/Him 🏳️🌈
Reposted by Jorge Almagro
Yearly Fuchs lab picnic 🧺
June 17, 2025 at 3:43 AM
Yearly Fuchs lab picnic 🧺
Reposted by Jorge Almagro
New paper alert! We report in @cp-cellmetabolism.bsky.social how serine regulates stem cell fate in physiology and upon wounding.
Good work, Jesse and collabs!
www.cell.com/cell-metabol...
Good work, Jesse and collabs!
www.cell.com/cell-metabol...
The integrated stress response fine-tunes stem cell fate decisions upon serine deprivation and tissue injury
Novak et al. discover that dietary serine impacts whether hair follicle stem cells
(HFSCs) prioritize hair growth or skin repair after injury. HFSCs gauge metabolic
stress using the ISR and accelerate...
www.cell.com
June 12, 2025 at 3:38 PM
New paper alert! We report in @cp-cellmetabolism.bsky.social how serine regulates stem cell fate in physiology and upon wounding.
Good work, Jesse and collabs!
www.cell.com/cell-metabol...
Good work, Jesse and collabs!
www.cell.com/cell-metabol...
Reposted by Jorge Almagro
Dos decenas de sociedades científicas han solicitado a la Comunidad de Madrid que impida urgentemente el “riesgo de destrucción” del Museo Olavide, una joya de la historia de la medicina que incluye unas 700 figuras de cera de pacientes reales
Decenas de sociedades científicas piden a la Comunidad de Madrid que impida la destrucción del Museo Olavide
Las instituciones recuerdan al Gobierno de Isabel Díaz Ayuso que la colección, una joya de la medicina expulsada por la Universidad Complutense, pertenece a una consejería. EL PAÍS graba los preparativos del traslado
elpais.com
June 11, 2025 at 1:02 PM
Dos decenas de sociedades científicas han solicitado a la Comunidad de Madrid que impida urgentemente el “riesgo de destrucción” del Museo Olavide, una joya de la historia de la medicina que incluye unas 700 figuras de cera de pacientes reales
It was heartwarming to join academic workers together in the fight against funding cuts, layoffs, and attacks to freedom of speech in our campuses. Scientists will not give up! @uaw.org
April 9, 2025 at 2:59 PM
It was heartwarming to join academic workers together in the fight against funding cuts, layoffs, and attacks to freedom of speech in our campuses. Scientists will not give up! @uaw.org
“…España, para cuyos ciudadanos la prioridad máxima debe ser la educación e investigación (40%, frente al 23% de media europea), mientras que la defensa cae al 20%”
elpais.com/internaciona...
elpais.com/internaciona...
Los españoles son los europeos menos preocupados por la seguridad y defensa, según el Eurobarómetro
La última encuesta de la UE subraya la importancia de mostrar “unidad” ante los desafíos globales
elpais.com
March 25, 2025 at 1:06 PM
“…España, para cuyos ciudadanos la prioridad máxima debe ser la educación e investigación (40%, frente al 23% de media europea), mientras que la defensa cae al 20%”
elpais.com/internaciona...
elpais.com/internaciona...
Submitting my PhD paper after 7.5 years 🫣
March 23, 2025 at 12:51 AM
Submitting my PhD paper after 7.5 years 🫣
Reposted by Jorge Almagro
Postdocs vs students @thefuchslab.bsky.social laser tag was barely a competition 😏
March 1, 2025 at 12:47 PM
Postdocs vs students @thefuchslab.bsky.social laser tag was barely a competition 😏
Yesterday we marched to oppose the hijacking of the NIH and the government by a nazi oligarch. Hands off the NIH!! No research, no cures ✊🏼
February 20, 2025 at 7:28 PM
Yesterday we marched to oppose the hijacking of the NIH and the government by a nazi oligarch. Hands off the NIH!! No research, no cures ✊🏼
Reposted by Jorge Almagro
Great news! @greatysp.bsky.social @jorgealmagro.bsky.social
🥳 Our 4th most downloaded article in 2024:
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel by @thefuchslab.bsky.social & colleagues
https://bit.ly/42Cvr...
@rockefelleruniv.bsky.social @hhmi.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel by @thefuchslab.bsky.social & colleagues
https://bit.ly/42Cvr...
@rockefelleruniv.bsky.social @hhmi.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel - Nature Reviews Cancer
In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic factors induce the epigenetic changes necessary for tumorigenesis.
bit.ly
February 11, 2025 at 2:29 PM
Great news! @greatysp.bsky.social @jorgealmagro.bsky.social
Reposted by Jorge Almagro
Congratulations to @jorgealmagro.bsky.social and @thefuchslab.bsky.social as well!! 🎊🎉🥳🥳 @rockefelleruniv.bsky.social @hhmi.bsky.social
🥳 Our 4th most downloaded article in 2024:
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel by @thefuchslab.bsky.social & colleagues
https://bit.ly/42Cvr...
@rockefelleruniv.bsky.social @hhmi.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel by @thefuchslab.bsky.social & colleagues
https://bit.ly/42Cvr...
@rockefelleruniv.bsky.social @hhmi.bsky.social @natureportfolio.bsky.social #NRCtop10of2024
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel - Nature Reviews Cancer
In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic factors induce the epigenetic changes necessary for tumorigenesis.
bit.ly
February 11, 2025 at 2:27 PM
Congratulations to @jorgealmagro.bsky.social and @thefuchslab.bsky.social as well!! 🎊🎉🥳🥳 @rockefelleruniv.bsky.social @hhmi.bsky.social
Reposted by Jorge Almagro
New #Review! 🥳
@jorgealmagro.bsky.social, @thefuchslab.bsky.social et al. discuss the role of stem cell mechanics during developmental processes and what happens when the mechanics of the stem cell niche are disrupted in cancer.
👉 go.nature.com/3EsJzJx
#StemCells #Mechanobiology #Cancer
@jorgealmagro.bsky.social, @thefuchslab.bsky.social et al. discuss the role of stem cell mechanics during developmental processes and what happens when the mechanics of the stem cell niche are disrupted in cancer.
👉 go.nature.com/3EsJzJx
#StemCells #Mechanobiology #Cancer
Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology
Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...
go.nature.com
February 5, 2025 at 10:33 AM
New #Review! 🥳
@jorgealmagro.bsky.social, @thefuchslab.bsky.social et al. discuss the role of stem cell mechanics during developmental processes and what happens when the mechanics of the stem cell niche are disrupted in cancer.
👉 go.nature.com/3EsJzJx
#StemCells #Mechanobiology #Cancer
@jorgealmagro.bsky.social, @thefuchslab.bsky.social et al. discuss the role of stem cell mechanics during developmental processes and what happens when the mechanics of the stem cell niche are disrupted in cancer.
👉 go.nature.com/3EsJzJx
#StemCells #Mechanobiology #Cancer
Reposted by Jorge Almagro
Very happy to see our review out in @natrevmcb.bsky.social!
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here 👇
www.nature.com/articles/s41...
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here 👇
www.nature.com/articles/s41...
Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology
Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...
www.nature.com
January 29, 2025 at 5:08 PM
Very happy to see our review out in @natrevmcb.bsky.social!
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here 👇
www.nature.com/articles/s41...
Here we discuss how stem cells exert forces to sculpt tissues in development and homeostasis, and how stem cell mechanics go awry upon malignant transformation. Read it here 👇
www.nature.com/articles/s41...
Reposted by Jorge Almagro
Our first 2025 paper!
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...
Shaping epithelial tissues by stem cell mechanics in development and cancer - Nature Reviews Molecular Cell Biology
Adult stem cells self-renew and differentiate to build, maintain and repair tissues. This Review discusses recent insights into the contribution of mechanical forces produced by epithelial stem cell a...
www.nature.com
January 29, 2025 at 5:00 PM
Our first 2025 paper!
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...
We discuss in @natrevmcb.bsky.social how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @jorgealmagro.bsky.social 👏
www.nature.com/articles/s41...
Paper of the Week! Norepinephrine oscillation during sleep regulates blood/CSF flow and waste clearance
With @kevinng.bsky.social @fesubtil.bsky.social @rysazaman.bsky.social
www.cell.com/cell/abstrac...
With @kevinng.bsky.social @fesubtil.bsky.social @rysazaman.bsky.social
www.cell.com/cell/abstrac...
January 16, 2025 at 3:34 PM
Paper of the Week! Norepinephrine oscillation during sleep regulates blood/CSF flow and waste clearance
With @kevinng.bsky.social @fesubtil.bsky.social @rysazaman.bsky.social
www.cell.com/cell/abstrac...
With @kevinng.bsky.social @fesubtil.bsky.social @rysazaman.bsky.social
www.cell.com/cell/abstrac...
What an exciting read 😍
January 15, 2025 at 11:26 PM
What an exciting read 😍
Reposted by Jorge Almagro
Caltech has set up a disaster relief fund for Caltech and Jet Propulsion Lab community members affected by the fires. Many lived in Altadena, which has been very heavily damaged. Please consider giving.
giving.caltech.edu/areas-to-sup...
giving.caltech.edu/areas-to-sup...
The Caltech and JPL Disaster Relief Fund
giving.caltech.edu
January 13, 2025 at 12:17 AM
Caltech has set up a disaster relief fund for Caltech and Jet Propulsion Lab community members affected by the fires. Many lived in Altadena, which has been very heavily damaged. Please consider giving.
giving.caltech.edu/areas-to-sup...
giving.caltech.edu/areas-to-sup...
Reading a textbook may give answers to such essential questions 😅
From Kandel et al. “Principles of Neural Science” (5th edition, before Piezo was identified as the master mechanosensor)
From Kandel et al. “Principles of Neural Science” (5th edition, before Piezo was identified as the master mechanosensor)
January 10, 2025 at 2:35 PM
Reading a textbook may give answers to such essential questions 😅
From Kandel et al. “Principles of Neural Science” (5th edition, before Piezo was identified as the master mechanosensor)
From Kandel et al. “Principles of Neural Science” (5th edition, before Piezo was identified as the master mechanosensor)
Reposted by Jorge Almagro
The Vienna BioCenter Summer School 2025 call is now open for applications from talented undergrads. It is the perfect preparation for students who are interested in graduate study in the life sciences arena. 9-week research project, accommodation and stipend for successful candidates.
January 10, 2025 at 11:15 AM
The Vienna BioCenter Summer School 2025 call is now open for applications from talented undergrads. It is the perfect preparation for students who are interested in graduate study in the life sciences arena. 9-week research project, accommodation and stipend for successful candidates.
Kicking off 2025 Paper of the Week with @kevinng.bsky.social & @fesubtil.bsky.social. Today we discussed our friend @martinaparigi.bsky.social et al. recent paper in @nature.com. How do epithelia unlink necessary drivers of regeneration from malignant transformation?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
January 9, 2025 at 8:37 PM
Kicking off 2025 Paper of the Week with @kevinng.bsky.social & @fesubtil.bsky.social. Today we discussed our friend @martinaparigi.bsky.social et al. recent paper in @nature.com. How do epithelia unlink necessary drivers of regeneration from malignant transformation?
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Congratulations Jimmy and @paigearnold.bsky.social 👏🏼
Thrilled to announce that two Rockefeller scientists have been named @hhmi.bsky.social Hanna Gray Fellows!
Congratulations to @paigearnold.bsky.social of the
Marraffini lab and Jim Castellanos of @thefuchslab.bsky.social and Weill Cornell Medicine on their awards!
Congratulations to @paigearnold.bsky.social of the
Marraffini lab and Jim Castellanos of @thefuchslab.bsky.social and Weill Cornell Medicine on their awards!
HHMI Names the 2024 Hanna Gray Fellows | HHMI
The cohort includes early career scientists working in research areas ranging from treatment-resistant cancers to how animals evolved to live on land. The HHMI Hanna H. Gray Fellows Program provides e...
www.hhmi.org
January 8, 2025 at 4:51 PM
Congratulations Jimmy and @paigearnold.bsky.social 👏🏼
Birding (and lynxing🤞🏼) with @atalavera.bsky.social somewhere in La Mancha…
January 2, 2025 at 3:18 PM
Birding (and lynxing🤞🏼) with @atalavera.bsky.social somewhere in La Mancha…
Reposted by Jorge Almagro
My first review of 2025 - Michael Mayer’s new Aida at the Met, for @thetimes.com
www.thetimes.com/culture/clas...
www.thetimes.com/culture/clas...
Aida review — the Met’s tacky show is like a night in a Luxor casino
Angel Blue’s impassioned singing as the heroine of Verdi’s opera is the highlight of a dispiriting night at the Metropolitan Opera in New York
www.thetimes.com
January 1, 2025 at 12:53 PM
My first review of 2025 - Michael Mayer’s new Aida at the Met, for @thetimes.com
www.thetimes.com/culture/clas...
www.thetimes.com/culture/clas...
Reposted by Jorge Almagro
Cancers may arise in tissues with a low mutational burden. It’s up to the microenvironment! We discussed this in @natrevcancer.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Beyond genetics: driving cancer with the tumour microenvironment behind the wheel - Nature Reviews Cancer
In their Review article, Fuchs and colleagues discuss how a single or a few mutations in adult cells can lead to invasive cancers without a high mutational burden, demonstrating that non-genetic ...
www.nature.com
December 31, 2024 at 1:44 PM
Cancers may arise in tissues with a low mutational burden. It’s up to the microenvironment! We discussed this in @natrevcancer.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...