@joreyna.bsky.social
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Our new tool for multi-modal data analysis! nipalsMCIA implements multiple co-inertia analysis (MCIA) via nonlinear partial iterative least squares (NIPALS). It's great for large datasets commonly found in multi-omic single-cell studies, and allows for easy out-of-sample embeddings.
Unlocking new insights with nipalsMCIA. This tool speeds up data analysis for big datasets by clustering and visualizing info faster than before. Check it out for both bulk and single cell data on Bioconductor with how-to guides and extras online.
nipalsMCIA: Flexible Multi-Block Dimensionality Reduction in R via Nonlinear Iterative Partial Least Squares.
Published in Bioinformatics (Oxford, England)
doi.org
January 31, 2025 at 10:31 PM
Our new tool for multi-modal data analysis! nipalsMCIA implements multiple co-inertia analysis (MCIA) via nonlinear partial iterative least squares (NIPALS). It's great for large datasets commonly found in multi-omic single-cell studies, and allows for easy out-of-sample embeddings.
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I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...
Method of the Year 2024: spatial proteomics - Nature Methods
Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease.
www.nature.com
December 6, 2024 at 8:52 PM
I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...
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Introducing Human Domainome v1, the largest and most comprehensive library of human protein variants to date, which maps the effects of +500K mutations across 522 domains. The study by @benlehner.bsky.social and Toni Beltran is out now in @nature.com. Illustration by @queralttolosa.bsky.social.
January 8, 2025 at 4:09 PM
Introducing Human Domainome v1, the largest and most comprehensive library of human protein variants to date, which maps the effects of +500K mutations across 522 domains. The study by @benlehner.bsky.social and Toni Beltran is out now in @nature.com. Illustration by @queralttolosa.bsky.social.
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Now available as preprint:
The ENCODE 4 expanded registry of regulatory elements
- 2.35M 🧍 human cCREs
- 927k 🐭 mouse cCREs
www.biorxiv.org/content/10.1...
Led by @moorejille.bsky.social, this preprint summarizes data and analyses generated by hundreds of contributors across ENCODE 4
The ENCODE 4 expanded registry of regulatory elements
- 2.35M 🧍 human cCREs
- 927k 🐭 mouse cCREs
www.biorxiv.org/content/10.1...
Led by @moorejille.bsky.social, this preprint summarizes data and analyses generated by hundreds of contributors across ENCODE 4
January 8, 2025 at 8:35 PM
Now available as preprint:
The ENCODE 4 expanded registry of regulatory elements
- 2.35M 🧍 human cCREs
- 927k 🐭 mouse cCREs
www.biorxiv.org/content/10.1...
Led by @moorejille.bsky.social, this preprint summarizes data and analyses generated by hundreds of contributors across ENCODE 4
The ENCODE 4 expanded registry of regulatory elements
- 2.35M 🧍 human cCREs
- 927k 🐭 mouse cCREs
www.biorxiv.org/content/10.1...
Led by @moorejille.bsky.social, this preprint summarizes data and analyses generated by hundreds of contributors across ENCODE 4
Reposted
If you use SHAP, LIME or Data Shapley, you might be interested in our new #neurips2024 paper. We introduce stochastic amortization to speed up feature + data attribution by 10x-100x 🚀 #XML
Surprisingly we can "learn to attribute" cheaply from noisy explanations! arxiv.org/abs/2401.15866
Surprisingly we can "learn to attribute" cheaply from noisy explanations! arxiv.org/abs/2401.15866
December 2, 2024 at 5:35 PM
If you use SHAP, LIME or Data Shapley, you might be interested in our new #neurips2024 paper. We introduce stochastic amortization to speed up feature + data attribution by 10x-100x 🚀 #XML
Surprisingly we can "learn to attribute" cheaply from noisy explanations! arxiv.org/abs/2401.15866
Surprisingly we can "learn to attribute" cheaply from noisy explanations! arxiv.org/abs/2401.15866
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Waiting for the day news agencies realise where their readers are, and add Bluesky to their share options.
December 1, 2024 at 9:33 AM
Waiting for the day news agencies realise where their readers are, and add Bluesky to their share options.
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Alexander Vindman is a patriot. Elon Musk, himself an oligarch, is drunk on power and out of control.
November 28, 2024 at 11:51 PM
Alexander Vindman is a patriot. Elon Musk, himself an oligarch, is drunk on power and out of control.
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The European Federation of Journalists representing over 320,000 journalists in Europe will no longer post on X.
Soon there will be no X, only Bluesky's.
Soon there will be no X, only Bluesky's.
November 28, 2024 at 9:49 PM
The European Federation of Journalists representing over 320,000 journalists in Europe will no longer post on X.
Soon there will be no X, only Bluesky's.
Soon there will be no X, only Bluesky's.
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The HPV vaccine has been recommended in the US since 2006. New study out today shows that cervical cancer deaths in young women in the years that followed have plummeted, decreasing 15% per year from 2013-2015.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Cervical Cancer Mortality Among US Women Younger Than 25 Years
This study examines trends in cervical cancer mortality in US women aged younger than 25 years before and after the introduction of human papillomavirus vaccines.
jamanetwork.com
November 28, 2024 at 2:43 AM
The HPV vaccine has been recommended in the US since 2006. New study out today shows that cervical cancer deaths in young women in the years that followed have plummeted, decreasing 15% per year from 2013-2015.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
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Blue Sky team, you're building something special and great here. Keep at it. Stick with it. And please don't sell it to an evil billionaire who's going to come around waving a lot of money to gobble it up.
Sincerely, a Happy Blue Sky user.
Sincerely, a Happy Blue Sky user.
November 27, 2024 at 5:45 AM
Blue Sky team, you're building something special and great here. Keep at it. Stick with it. And please don't sell it to an evil billionaire who's going to come around waving a lot of money to gobble it up.
Sincerely, a Happy Blue Sky user.
Sincerely, a Happy Blue Sky user.
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We are proud to announce a collaboration with UK Biobank to create the world’s first large-scale #epigenetic dataset of 50k participants. The dataset will unlock crucial insights into how #epigenetics drives disease & the breakthroughs to treat them.
Read more: nanoporetech.com/news/oxford-...
Read more: nanoporetech.com/news/oxford-...
November 27, 2024 at 9:16 AM
We are proud to announce a collaboration with UK Biobank to create the world’s first large-scale #epigenetic dataset of 50k participants. The dataset will unlock crucial insights into how #epigenetics drives disease & the breakthroughs to treat them.
Read more: nanoporetech.com/news/oxford-...
Read more: nanoporetech.com/news/oxford-...
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Isn’t it funny how the U.S. media is suddenly posting stories about the improving inflation picture now that the election is over? 🧐
November 26, 2024 at 2:01 PM
Isn’t it funny how the U.S. media is suddenly posting stories about the improving inflation picture now that the election is over? 🧐
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This needs to be said, loud, and often.
November 25, 2024 at 5:20 PM
This needs to be said, loud, and often.
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Remember new users are coming on daily, unsure of engagement. The more posts you like and reply to, the strong the platform becomes !
November 25, 2024 at 7:05 PM
Remember new users are coming on daily, unsure of engagement. The more posts you like and reply to, the strong the platform becomes !
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If you have a website, a Substack, a YouTube channel, Twitch, IG, FB, or newsletter, you have a vested interest in moving over to Bluesky where your external links aren't throttled. Elon isn't looking out for you; he's looking out for Elon.
Elon admits that any post on X with a link is throttled
He advises you to upload content directly to X instead, where he can monetize it
Musk is the richest person in the world and his view is everyone should work for him for free
He advises you to upload content directly to X instead, where he can monetize it
Musk is the richest person in the world and his view is everyone should work for him for free
November 25, 2024 at 4:48 PM
If you have a website, a Substack, a YouTube channel, Twitch, IG, FB, or newsletter, you have a vested interest in moving over to Bluesky where your external links aren't throttled. Elon isn't looking out for you; he's looking out for Elon.
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The Founders put ‘advice and consent’ in the Constitution for a reason. They wanted Senators to have oversight over Cabinet picks of a President to ensure that they were properly vetted. Winning an election 49.89%-48.24 doesn’t dispense with that constitutional responsibility.
November 20, 2024 at 8:18 PM
The Founders put ‘advice and consent’ in the Constitution for a reason. They wanted Senators to have oversight over Cabinet picks of a President to ensure that they were properly vetted. Winning an election 49.89%-48.24 doesn’t dispense with that constitutional responsibility.
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Twitter is alive and well - it's called "Bluesky" - enjoy.
X is now officially called "hellsite"
Update your lexicons people, stay rizz.
X is now officially called "hellsite"
Update your lexicons people, stay rizz.
November 19, 2024 at 3:52 PM
Twitter is alive and well - it's called "Bluesky" - enjoy.
X is now officially called "hellsite"
Update your lexicons people, stay rizz.
X is now officially called "hellsite"
Update your lexicons people, stay rizz.
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Jay on Bluesky: We've been scaling up. There's been about a million people joining a day for the past week
November 20, 2024 at 4:52 AM
Jay on Bluesky: We've been scaling up. There's been about a million people joining a day for the past week
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Yes. This. Each time I post about the hypocrisy I'm getting these kinds of cynical responses, and really, stop it. I get that everyone copes in their own way, but don't pre-give in. Fight for your actual rights. Call out the hypocrisy. Not to convince them, but to remind everyone else.
Getting a lot of replies along the lines of "oh, you rube, you still think the law matters" and it feels strategically foolish to just concede that it doesn't. Contest everything. Expose the hypocrisy.
November 18, 2024 at 3:36 AM
Yes. This. Each time I post about the hypocrisy I'm getting these kinds of cynical responses, and really, stop it. I get that everyone copes in their own way, but don't pre-give in. Fight for your actual rights. Call out the hypocrisy. Not to convince them, but to remind everyone else.
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Elon and his team changed the X algorithm so that it would boost pro-Republican accounts as well as Elon's own account.
Remember when he fumed about Twitter Files and "liberal bias"? Elon's X was MUCH worse.
Remember when he fumed about Twitter Files and "liberal bias"? Elon's X was MUCH worse.
1/ X's algorithm was changed in mid-July 2024 to systematically boost Republican-leaning accounts and Elon Musk's own account following his endorsement of Donald Trump, according to a newly released computational study of engagement from the Queensland University of Technology.⬇️
November 16, 2024 at 12:17 PM
Elon and his team changed the X algorithm so that it would boost pro-Republican accounts as well as Elon's own account.
Remember when he fumed about Twitter Files and "liberal bias"? Elon's X was MUCH worse.
Remember when he fumed about Twitter Files and "liberal bias"? Elon's X was MUCH worse.