Jooho Lee
@jooho.bsky.social
Cancer Research, Neuro-oncology, Radiation Oncology
Radiation Oncologist
Professor at Seoul National University, South Korea
Like classical music, playing tennis, travel
Radiation Oncologist
Professor at Seoul National University, South Korea
Like classical music, playing tennis, travel
Reposted by Jooho Lee
Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling: Cell www.cell.com/cell/fulltex...
Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling
Midbrain cholinergic neuronal activity promotes the proliferation of both oligodendrocyte
precursor cells and diffuse midline glioma (DMG) cells in a circuit-dependent manner,
mediated by muscarinic M...
www.cell.com
June 20, 2025 at 2:03 AM
Cholinergic neuronal activity promotes diffuse midline glioma growth through muscarinic signaling: Cell www.cell.com/cell/fulltex...
Reposted by Jooho Lee
Fun writing this piece with @bartegiani.bsky.social!
New online! Searching for the origin of human brain tumours
Searching for the origin of human brain tumours
Nature Reviews Genetics, Published online: 28 May 2025; doi:10.1038/s41576-025-00858-7In this Journal Club, Delilah Hendriks and Benedetta Artegiani recall a 2018 paper by Lee et al. that combined data from human patients and experimental model systems to reveal the complexities of how brain tumours originate.
www.nature.com
May 28, 2025 at 8:37 PM
Fun writing this piece with @bartegiani.bsky.social!
Reposted by Jooho Lee
Estimating de novo mutation rate over four generations from total 28 individuals. 👏
Human de novo mutation rates from a four-generation pedigree reference www.nature.com/articles/s41... 🧬🖥️🧪
May 3, 2025 at 2:11 AM
Estimating de novo mutation rate over four generations from total 28 individuals. 👏
Reposted by Jooho Lee
We are looking to recruit new postdocs! Please check verhaaklab.com/archive/2025....
postdoc opportunity - join our team! · Verhaak Lab
The Verhaak lab in the Department of Neurosurgery at the Yale School of Medicine is looking to recruit a postdoctoral associate who will help us develop new therapeutic approaches to treat patients wi...
verhaaklab.com
March 20, 2025 at 2:05 PM
We are looking to recruit new postdocs! Please check verhaaklab.com/archive/2025....
Excited to share our latest paper in Molecular Cancer! We reveal how recurrent glioblastomas originate from distant ventricular regions and identify potential therapeutic targets. Check it out! 🔬🧠
🔗 molecular-cancer.biomedcentral.com/articles/10....
🔗 molecular-cancer.biomedcentral.com/articles/10....
Distant origin of glioblastoma recurrence: neural stem cells in the subventricular zone serve as a source of tumor reconstruction after primary resection - Molecular Cancer
Glioblastoma (GBM) is the most aggressive and common type of primary malignant brain cancer in adults. GBM often recurs locally near the resection cavity (RC) following the surgical removal of primary...
molecular-cancer.biomedcentral.com
March 4, 2025 at 4:22 AM
Excited to share our latest paper in Molecular Cancer! We reveal how recurrent glioblastomas originate from distant ventricular regions and identify potential therapeutic targets. Check it out! 🔬🧠
🔗 molecular-cancer.biomedcentral.com/articles/10....
🔗 molecular-cancer.biomedcentral.com/articles/10....
Reposted by Jooho Lee
A Review in Nature Medicine examines how organoid research is moving beyond developmental and disease biology, driving insights into current and emerging health threats and enabling personalized and regenerative medicine applications. 🔒
Clinical applications of human organoids - Nature Medicine
Organoid research is moving beyond developmental and disease biology, driving insights into current and emerging health threats and enabling personalized and regenerative medicine applications.
go.nature.com
February 18, 2025 at 2:32 PM
A Review in Nature Medicine examines how organoid research is moving beyond developmental and disease biology, driving insights into current and emerging health threats and enabling personalized and regenerative medicine applications. 🔒
Reposted by Jooho Lee
📣 Open computational PhD & Postdoc positions!
Excited about the open positions as part of our newly funded Emmy Noether Group are online now under
kocakavuklab.vercel.app/joinus
📢 Please RT (what's the bsky equivalent here?) and distribute !
👇A quick instruction on how to apply
Excited about the open positions as part of our newly funded Emmy Noether Group are online now under
kocakavuklab.vercel.app/joinus
📢 Please RT (what's the bsky equivalent here?) and distribute !
👇A quick instruction on how to apply
February 19, 2025 at 2:42 PM
📣 Open computational PhD & Postdoc positions!
Excited about the open positions as part of our newly funded Emmy Noether Group are online now under
kocakavuklab.vercel.app/joinus
📢 Please RT (what's the bsky equivalent here?) and distribute !
👇A quick instruction on how to apply
Excited about the open positions as part of our newly funded Emmy Noether Group are online now under
kocakavuklab.vercel.app/joinus
📢 Please RT (what's the bsky equivalent here?) and distribute !
👇A quick instruction on how to apply
Reposted by Jooho Lee
Great story; Gliomagenesis mimics an injury response orchestrated by neural crest-like cells www.nature.com/articles/s41...
Gliomagenesis mimics an injury response orchestrated by neural crest-like cells - Nature
A study using glioblastoma mouse models, serial magnetic resonance imaging and single-cell profiling details changes in the identity and balance of cellular states from initiation of tumorigenesis to ...
www.nature.com
January 3, 2025 at 4:28 AM
Great story; Gliomagenesis mimics an injury response orchestrated by neural crest-like cells www.nature.com/articles/s41...
Reposted by Jooho Lee
Cancer #aneuploidy observed in ~normal breast tissue from healthy women. 👏 from Lin & Wang, Navin Lab www.nature.com/articles/s41...
Related: Context is everything in the eyes of #evolution. www.nature.com/articles/s41...
Related: Context is everything in the eyes of #evolution. www.nature.com/articles/s41...
Normal breast tissues harbour rare populations of aneuploid epithelial cells - Nature
Using single-cell DNA sequencing we show that most healthy women harbour rare populations of aneuploid epithelial cells with copy number alteration events in their breast tissue that expand and accumu...
www.nature.com
November 21, 2024 at 12:04 AM
Cancer #aneuploidy observed in ~normal breast tissue from healthy women. 👏 from Lin & Wang, Navin Lab www.nature.com/articles/s41...
Related: Context is everything in the eyes of #evolution. www.nature.com/articles/s41...
Related: Context is everything in the eyes of #evolution. www.nature.com/articles/s41...
Congrats to Postdoc Xue Li in our lab for the Young Investor Award! She will present our work "DISTANT ORIGIN OF GLIOBLASTOMA RECURRENCE: NEURAL STEM CELLS SERVE AS A SOURCE OF TUMOR RECONSTRUCTION AFTER RESECTION” this morning at 830AM in General Assembly A #SNO2024
November 24, 2024 at 1:20 PM
Congrats to Postdoc Xue Li in our lab for the Young Investor Award! She will present our work "DISTANT ORIGIN OF GLIOBLASTOMA RECURRENCE: NEURAL STEM CELLS SERVE AS A SOURCE OF TUMOR RECONSTRUCTION AFTER RESECTION” this morning at 830AM in General Assembly A #SNO2024