Lightnews — Scholar-powered news

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · 24d

With my colleague Dr. Jens Kreth representing OHSU and the USA at what was a fantastic conference!
#microbiology #dentistry #immunology

1 3

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Sep 13

After spending 7 months earlier this year visiting our lab at @ohsunews.bsky.social on a scholarship, Dr. Felipe Farias da Silva recently presented his work with us at the 2025 meeting of the Brazilian Society of Dental Research. Way to go Felipe! #microbiology #dentistry

1 1

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Aug 21

This summer, we hosted Sadie Drucker (Scripps Coll.) and Michelle Lee (Oregon State Univ.), through our NIH-funded DORS program. They did an amazing job, and Sadie won Best Poster at the OHSU Summer Internship Symposium! We wish them the best on the next step in their careers!

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Aug 20

Microbiology faculty welcoming incoming OHSU President, Dr. Shereef Elnahal, at a celebration for the Knight family’s $2B donation to our university to fight cancer.
#microbiology

1 3

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Aug 16

The Baker Lab at OHSU, Summer 2025. 🦠🔬🧫🧪
#microbiology

1 4

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Jul 28

Reposting the link as the above one only allowed a limited number of views

journals.asm.org/doi/10.1128/...

The salivary virome during childhood dental caries | mSphere

Dental caries is the most common chronic infectious disease worldwide and is caused by dysbiosis of the oral microbiome featuring an increased abundance of acid-tolerant, acid-producing, and biofilm-f...

journals.asm.org

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Jul 28

The viral component of the microbiome has been understudied compared to the bacterial component, despite playing a crucial role in both microbial ecology and human health. We also discovered 478 novel species-level viruses. Congratulations to Jonah Tang on his first first-author publication!

1

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Jul 28

New publication!
We examined the viruses present in the human oral microbiome of children with severe cavities versus healthy teeth and there was a significant difference in the diversity of viruses present in the groups!

journals.asm.org/eprint/FDPZ4...

The salivary virome during childhood dental caries | mSphere

Dental caries is the most common chronic infectious disease worldwide and is caused by dysbiosis of the oral microbiome featuring an increased abundance of acid-tolerant, acid-producing, and biofilm-f...

journals.asm.org

1

Reposted by Jonathon L. Baker, Ph.D.

ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · Jul 21

If high quality treatment is provided to everyone with bacterial infections + innovative new antibiotics funded ...

By 2050:

Health costs ⬇️ $97 billion
The economy ⬆️ $960 billion
Generated health benefits 🟰 $680 billion to countries

Return on Investment 🟰 28 to 1

www.cgdev.org/publication/...

1 4 6

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Jun 15

Excited to see this out! We identified a novel regulator of fatty acid composition in S. pneumoniae (among a lot of other cool stuff in the paper)!

Jan-Willem Veening @veeninglab.com · Jun 15

Some positive news in troubled times: New preprint by Vincent de Bakker, Xue Liu @jonbakerlab.bsky.social Infection-mimicking conditions+transcriptomics/proteomics/'essentialomics'/lipidomics shows many cool things!
www.biorxiv.org/content/10.1...

Multi-omics profiling reveals atypical sugar utilization and identifies a key membrane composition regulator in Streptococcus pneumoniae

The human body comprises many different microenvironments, each with their own challenges for microorganisms to overcome in order to survive, and possibly cause infection. The human pathogen Streptoco...

www.biorxiv.org

2 4

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · May 30

The Baker Lab at OHSU, Spring 2025.

🧬🔬🧫🦠 #microbiology

1 1

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · May 26

Congratulations to our high school intern, Daniela, and our Research Assistants, Matthew and Jonah, on publishing their pilot study on the impact of beetroot supplement on an in-vitro microbiome of e-cigarette users! #microbiology #dentistry

www.tandfonline.com/doi/full/10....

The effect of Beta vulgaris on an in vitro oral microbiome of electronic cigarette users

Although touted as a safer alternative to cigarette smoking, electronic cigarette usage has been increasingly linked to a myriad of health issues and appears to impact the oral microbiome. Meanwhil...

www.tandfonline.com

1

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · May 9

I was interviewed by Business Insider magazine as part of an article about the impact of the oral microbiome on overall human health!
#microbiology #dentistry

www.businessinsider.com/oral-microbi...

Cleaning your teeth could help you live longer: meet your oral microbiome

You may know that caring for your gut microbiome could help you live longer. But brushing and flossing your teeth is also a potential shortcut to better health.

www.businessinsider.com

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · May 2

New publication!
Our findings reveal that the specificity of several FISH probes is compromised, with cross-species hybridization being more common than previously assumed as more genomic data becomes available. #microbiology

onlinelibrary.wiley.com/doi/10.1111/...

Shining Light on Oral Biofilm Fluorescence In Situ Hybridization (FISH): Probing the Accuracy of In Situ Biogeography Studies

The oral biofilm has been instrumental in advancing microbial research and enhancing our understanding of oral health and disease. Recent developments in next-generation sequencing have provided deta...

onlinelibrary.wiley.com

1 1

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Mar 26

Exciting news! Our very first hire, Jonah Tang, was accepted into and will be joining the Bioinformatics Graduate Program at the University of Oregon! After 1.5 years in the lab, Jonah is already an author on 3 submitted publications and several more that are in preparation. Congratulations Jonah!

4

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Mar 11

Tomorrow, 1:30pm. AADOCR in NYC.

Honored to be a speaker alongside @jmarkwelch.bsky.social and @mbio.bsky.social Editor in Chief Marvin Whiteley.
#microbiology #dentistry

1 2

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Mar 5

The Baker Lab was very well represented at OHSU School of Dentistry Research Day!

I’m so proud of my team!
#microbiology
#dentistry

2

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Feb 18

Excited to speak at the University of Colorado School of Medicine this Friday!

#microbiology

1

Reposted by Jonathon L. Baker, Ph.D.

ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · Feb 10

𝗪𝗼𝗿𝘁𝗵 𝗦𝗵𝗮𝗿𝗶𝗻𝗴:

𝗥𝗼𝗹𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗡𝗜𝗛 𝗶𝗻
𝗦𝘂𝘀𝘁𝗮𝗶𝗻𝗶𝗻𝗴 𝘁𝗵𝗲 𝗘𝗰𝗼𝗻𝗼𝗺𝘆

www.unitedformedicalresearch.org/wp-content/u...

1 19 24

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Jan 26

Happy to share that I was a Finalist for the OHSU 2024 Distinguished Faculty Award in Collaboration! In the last 5 years, collaborated with 83 co-authors from 29 institutions in 9 countries. Congratulations to the other finalists and winner, Dr. Lyndie Foster Page!
www.linkedin.com/feed/update/...

OHSU School of Dentistry on LinkedIn: #dentistry #ohsuschoolofdentistry #ohsudentistry #ohsu #ohsuresearch

Oregon Health & Science University celebrated its 2024 Distinguished Faculty Award winners recently and the OHSU School of Dentistry had a winner and several…

www.linkedin.com

2

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Dec 19

A great week at FOP-UNICAMP! We brainstormed ways to get dentists involved in National Action Plans being implemented to combat antibiotic resistance (AMR), showed how to use sequencing to analyze AMR, and also practiced developing grant proposals with the students 🇳🇴🇧🇷🇺🇸

1 5 9

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Dec 19

In Brazil this week at the Faculdade de Odontologia de Piracicaba with my good friend @AMRTwilight to promote awareness of antimicrobial resistance and antibiotic stewardship.

who.int/campaigns/worl…

World Antimicrobial Awareness Week 2024

World Antimicrobial Awareness Week aims to increase awareness of global antimicrobial resistance (AMR) and to encourage best practices.

www.who.int

2 5

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Dec 19

First start-to-finish, completely in-house RNA-seq in our lab this month, what a time to be alive.

4

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Dec 19

Last month I hosted the annual Symposium for our RESISFORCE Project here at @OHSUNews. We hosted 25 researchers from 🇳🇴🇧🇷🇮🇳🇨🇦🇯🇵🇺🇸 to share their research and build collaborations to address the global challenge of #AntimicrobialResistance. Thanks to @forskningsradet for funding!

2 5

Jonathon L. Baker, Ph.D. @jonbakerlab.bsky.social · Dec 19

New publication! Yujiro Hirose and our team from the @victornizet and @bpalsson labs developed a #genome scale model a hyperinvasive strain of #streptococcus #pyogenes that will help guide future research and therapeutic strategies. #microbiology

journals.asm.org/doi/10.1128/ms…

A genome-scale metabolic model of a globally disseminated hyperinvasive M1 strain of Streptococcus pyogenes | mSystems

Genome-scale models (GEMs) play a crucial role in investigating bacterial metabolism, predicting the effects of inhibiting specific metabolic genes and pathways, and aiding in the identification of potential drug targets. Here, we have developed the first ...

journals.asm.org

3