Johnson Mak
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johnsonmak.bsky.social
Johnson Mak
@johnsonmak.bsky.social
31 followers 38 following 3 posts
Professor (Institute for Biomedicine & Glycomics, Griffith University). Virology, Molecular Biology, Cell Biology, Biotechnology, Infectious Diseases
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johnsonmak.bsky.social
Glycan-induced structural activation of HPV rdcu.be/d1IVn
Glycan-induced structural activation softens the human papillomavirus capsid for entry through reduction of intercapsomere flexibility
Nature Communications - The study shows that HPV activation requires a minimum glycan length, which enlarges and softens the virus. Using virological assays, AFM, and HDX-MS, the authors propose a...
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November 28, 2024 at 1:51 AM
johnsonmak.bsky.social
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Virus-modified paraspeckle-like condensates are hubs for viral RNA processing and their formation drives genomic instability
Nature Communications - KSHV modifies paraspeckles during its lytic replication cycle. They enhance virus replication by functioning as hubs for viral RNA processing and their modification is...
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November 28, 2024 at 1:35 AM
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Cryo-EM structure of single-layered nucleoprotein-RNA complex from Marburg virus
Nature Communications - Zinzula et al. reconstituted the helical ribonucleoprotein complex of Marburg virus in vitro, and determined its structure by cryo-electron microscopy in a single-layer...
rdcu.be
November 28, 2024 at 1:28 AM