John Prensner
@johnprensner.bsky.social
Pediatric neuro-oncologist, Asst Prof U-Michigan | Cancer researcher | RNA & ribosome enthusiast | Broad Institute, DFCI alum | book & music & tea lover | Dad | Views are mine (he/him). https://prensnerlab.org
Reposted by John Prensner
The pangenome resources and genome assembly/inference approaches we are building will eventually enable complete, personalized “T2T” genomes for everyone. This is the thesis of the Q100 project (www.biorxiv.org/content/10.1...) and what my group is currently working towards. Stay tuned... [10/10]
A complete diploid human genome benchmark for personalized genomics
Human genome resequencing typically involves mapping reads to a reference genome to call variants; however, this approach suffers from both technical and reference biases, leaving many duplicated and ...
www.biorxiv.org
October 13, 2025 at 8:17 PM
The pangenome resources and genome assembly/inference approaches we are building will eventually enable complete, personalized “T2T” genomes for everyone. This is the thesis of the Q100 project (www.biorxiv.org/content/10.1...) and what my group is currently working towards. Stay tuned... [10/10]