Johanna Siehler
johannasiehler.bsky.social
Johanna Siehler
@johannasiehler.bsky.social
Stem Cell Research Scientist at Vertex Pharmaceuticals working on Type 1 Diabetes. Helmholtz Munich alumni.
Reposted by Johanna Siehler
Inexplicably, US administration has launched an unprecedented assault on science, on research institutions & on vital international organizations & initiatives.

An assault on science anywhere is an assault on science everywhere; the global community must unite
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www.nature.com/articles/d41...
Trump 2.0: an assault on science anywhere is an assault on science everywhere
US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.
www.nature.com
February 25, 2025 at 7:48 PM
Reposted by Johanna Siehler
We've summarised the landscape of human pluripotent stem cell trials worldwide in a review in Cell Stem Cell. Fun fact: Over 1200 patients have to date received treatment with hPSC products in 116 different trials, and more than 100 billion hPSC-derived cells have been dosed! doi.org/10.1016/j.st...
January 7, 2025 at 11:16 PM
Reposted by Johanna Siehler
Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
doi.org/10.1038/s422...
A tremendous collaborative effort led by JohannaSiehler, Sara Bilekova and other members of the Lickert lab @heikolickert.bsky.social
Inceptor binds to and directs insulin towards lysosomal degradation in β cells - Nature Metabolism
The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.
doi.org
November 25, 2024 at 11:16 AM
Reposted by Johanna Siehler
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️

So how can we ever achieve #gender #equality?

We discuss various strategies in this #Cell Commentary

#WomeninSTEM

www.cell.com/cell/fulltex...
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November 25, 2024 at 12:38 PM