Joachim Nielsen
@joachimnielsen.bsky.social
Associate Professor in Muscle Physiology and Metabolism. University of Southern Denmark.
The data show that eight weeks of HIIT training led to a 7% increase in mitochondrial cristae density, demonstrating cristae plasticity.
Importantly, this plasticity was also observed in patients with type 2 diabetes, highlighting its relevance for metabolic health.
Importantly, this plasticity was also observed in patients with type 2 diabetes, highlighting its relevance for metabolic health.
September 30, 2025 at 2:03 PM
The data show that eight weeks of HIIT training led to a 7% increase in mitochondrial cristae density, demonstrating cristae plasticity.
Importantly, this plasticity was also observed in patients with type 2 diabetes, highlighting its relevance for metabolic health.
Importantly, this plasticity was also observed in patients with type 2 diabetes, highlighting its relevance for metabolic health.
Martin and Amalie manually analysed ~11,000 mitochondrial profiles for cristae density using classical stereology: counting intersections with cristae and points with mitochondria.
Each biopsy typically included >100 profiles, with a minimum cut-off of 49 profiles to ensure a CE ≤ 0.05.
Each biopsy typically included >100 profiles, with a minimum cut-off of 49 profiles to ensure a CE ≤ 0.05.
September 30, 2025 at 2:02 PM
Martin and Amalie manually analysed ~11,000 mitochondrial profiles for cristae density using classical stereology: counting intersections with cristae and points with mitochondria.
Each biopsy typically included >100 profiles, with a minimum cut-off of 49 profiles to ensure a CE ≤ 0.05.
Each biopsy typically included >100 profiles, with a minimum cut-off of 49 profiles to ensure a CE ≤ 0.05.
Elegant study on glycogen using the one-legged exercise model:
Exercise- and diet-induced glycogen depletion impairs performance during one-legged constant-load, high-intensity exercise in humans
Thomassen, McKenna, Olmedillas, Wyckelsma, Bangsbo, Nordsborg
www.frontiersin.org/journals/phy...
Exercise- and diet-induced glycogen depletion impairs performance during one-legged constant-load, high-intensity exercise in humans
Thomassen, McKenna, Olmedillas, Wyckelsma, Bangsbo, Nordsborg
www.frontiersin.org/journals/phy...
August 24, 2025 at 8:47 AM
Elegant study on glycogen using the one-legged exercise model:
Exercise- and diet-induced glycogen depletion impairs performance during one-legged constant-load, high-intensity exercise in humans
Thomassen, McKenna, Olmedillas, Wyckelsma, Bangsbo, Nordsborg
www.frontiersin.org/journals/phy...
Exercise- and diet-induced glycogen depletion impairs performance during one-legged constant-load, high-intensity exercise in humans
Thomassen, McKenna, Olmedillas, Wyckelsma, Bangsbo, Nordsborg
www.frontiersin.org/journals/phy...
Join our PhD course in metabolism and EC coupling.
November 10-15. University of Southern Denmark.
Enrol here: www.sdu.dk/en/forskning...
November 10-15. University of Southern Denmark.
Enrol here: www.sdu.dk/en/forskning...
August 13, 2025 at 6:14 PM
Join our PhD course in metabolism and EC coupling.
November 10-15. University of Southern Denmark.
Enrol here: www.sdu.dk/en/forskning...
November 10-15. University of Southern Denmark.
Enrol here: www.sdu.dk/en/forskning...
News from our lab: 4 weeks of altitude decreases skeletal muscle mitochondrial cristae density in humans (but mitochondrial respiration increased). Great work by Camilla Schytz, Carsten Lundby, and colleagues. doi.org/10.1152/japp...
July 4, 2025 at 7:38 PM
News from our lab: 4 weeks of altitude decreases skeletal muscle mitochondrial cristae density in humans (but mitochondrial respiration increased). Great work by Camilla Schytz, Carsten Lundby, and colleagues. doi.org/10.1152/japp...
Our latest: Quantitative details on lipid droplet-mitochondrial contact in human skeletal muscle
doi.org/10.1152/ajpc...
doi.org/10.1152/ajpc...
June 15, 2025 at 8:08 AM
Our latest: Quantitative details on lipid droplet-mitochondrial contact in human skeletal muscle
doi.org/10.1152/ajpc...
doi.org/10.1152/ajpc...
First day of new study! We aim to investigate if #Durability is related to muscle glycogen and further to an interaction between individual muscle fiber #Mitochondria and #Glycogen. TEM analyses of +1,000 muscle fibers. Headed by PhD fellow Anders Aagaard Hansen @andersaagaard.bsky.social
#MyoBlue
#MyoBlue
January 17, 2025 at 4:19 PM
First day of new study! We aim to investigate if #Durability is related to muscle glycogen and further to an interaction between individual muscle fiber #Mitochondria and #Glycogen. TEM analyses of +1,000 muscle fibers. Headed by PhD fellow Anders Aagaard Hansen @andersaagaard.bsky.social
#MyoBlue
#MyoBlue