Jingyi Wu
@jingyiwu.bsky.social
biologist in epigenetics and genomics
passionate about understanding cancer and discovering a cure
moving from DFCI to BIDMC
passionate about understanding cancer and discovering a cure
moving from DFCI to BIDMC
Reposted by Jingyi Wu
New research from @jingyiwu.bsky.social, @drbradb.bsky.social, @suvalab.bsky.social, and others shows how slow-growing brain tumors called gliomas turn aggressive and deadly. The team pinpointed genetic shifts that push these tumors into the fast lane. #Science
Researchers identify source of a brain cancer’s deadly transformation
Slow-growing glioma tumors become more aggressive when their cells shift identities and acquire new genetic mutations.
www.broadinstitute.org
November 21, 2024 at 3:30 PM
New research from @jingyiwu.bsky.social, @drbradb.bsky.social, @suvalab.bsky.social, and others shows how slow-growing brain tumors called gliomas turn aggressive and deadly. The team pinpointed genetic shifts that push these tumors into the fast lane. #Science
Our work reveals that as IDH mutant gliomas progress, their cell states and key drivers change. www.nature.com/articles/s43...
Evolving cell states and oncogenic drivers during the progression of IDH-mutant gliomas - Nature Cancer
Wu et al. perform single-cell analyses to explore the switch from low-grade to high-grade isocitrate-dehydrogenase-mutant glioma and show that it is characterized by oligodendrocyte progenitor cell-li...
www.nature.com
November 21, 2024 at 6:00 PM
Our work reveals that as IDH mutant gliomas progress, their cell states and key drivers change. www.nature.com/articles/s43...