Also, as a community, if we can create a space where everyone can upload their images where MicroSAM fails at the beginning, together with their manually fixed masks, I believe MicroSAM could become a really off-the-shelf tool for the entire community in no time.

Analyzing LSFM images: LSFM is still one of our top priority in image analysis method development thanks to the support from BMBF. Some new cool tools are coming, including one great collaboration with Dr. Peng at Helmholtz AI.

(7) Microscopy Data Portal: thanks to the open source and FAIR effort in the bioimaging community, we built two data portals (alpha version) in 2024, one for cell migration (cellmigration.isas.de) and one for lightsheet images (lsfm.isas.de). More data are coming in 2025, including annotations. (8)

Thanks for the trust from our biology collaborators. (6) Multimodal AI for biology: Thanks to our institution’s support and our collaborators in the AI community, our group is able to explore along the direction of Multimodal AI Models, including a short comment paper on Nature Methods special issue

this direction will be delivered in 2025. (5) Bioimage Compression: Our preliminary study on microscopy image compression with AI is accepted to Biological Imaging and more works to appear soon. We find that microscopy image compression is much more than saving storage, but facilitating researches.

(4) Data Centric AI for bioimaging: We believe the data centric mindset is important for bioimaging AI, especially in the era of foundation models. Our preliminary workflow is accepted to the BVM conference (with OA paper). Thanks to many collaborators around the world, more works along

my early days in computer science and biology. (3) VR/AR for biology: Thanks to great collaboration between our team at ISAS and the IKIM team in Essen, we started our journey to explore mixed reality for biomedical research, leading to two publications. More focus on biology will follow in 2025.

In late 2024, I joined the inspiring I2K and @globias.bsky.social GloBIAS meetings. The community is amazing! (2) Flashback: I finally met my friends at the Allen Institute in Feb in Seattle and met my PhD advisor at the ISBI conference after many years. I really appreciate what they taught me in

I’m very sorry for your loss. deepest condolences …