Jack Underwood
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jfgunderwood.bsky.social
Jack Underwood
@jfgunderwood.bsky.social
1.6K followers 960 following 25 posts
WCAT Forensic Psychiatry Registrar.
Wellcome @gw4cat.bsky.social alumnus.
Researching mental health in neurodevelopmental disorders via genomics/ epi/ big(ish) data at NMHII & CNGG, Cardiff University.
Uncertainty | Consciousness | Mistake not...
Posts Replies Media Videos
Reposted by Jack Underwood
cacna1c.bsky.social
New expert-led guidance clarifies terminology for pathogenic CACNA1C variants, defining Timothy Syndrome and introducing CACNA1C-Related Disorders (CRDs). Read the preprint: www.researchsquare.com/article/rs-8...
#CACNA1C #TimothySyndrome #RareDisease
November 19, 2025 at 3:29 PM
Reposted by Jack Underwood
autisminadulthood.bsky.social
“The Experience of Itch in Autistic Adults: An Online Survey” by Tackley et al (2025) finds that autistic adults report greater itch severity and itch-related impact on their daily life than non-autistic adults.

FREE until 20th June

www.liebertpub.com/doi/10.1089/...
A close-up of a person scratching their arm with their opposite hand.
June 5, 2025 at 8:39 PM
Reposted by Jack Underwood
gtackley.bsky.social
doi.org/10.1089/aut.... We asked autistic and non-autisitc people if they suffered from itch. Autistic people reported more itch, at a greater severity, and with a far greater impact. #autism #sensory
The Experience of Itch in Autistic Adults: An Online Survey | Autism in Adulthood
Background: The self-reported experience of itch for autistic people has not been studied. Anecdote, theory, and emerging research suggest that itch experience is different in autistic people, with ne...
doi.org
May 17, 2025 at 9:03 PM
Reposted by Jack Underwood
martinmckee.bsky.social
3 elections in as many weeks. Centre left parties in two of them take on populist right and win, in 3rd they emulate populists and lose. Could there be a lesson here? And is there even a remote chance U.K. Labour might see it?
May 3, 2025 at 10:51 AM
Reposted by Jack Underwood
eberllab.bsky.social
When you were asked to return the corrected page proofs within 48 hours but four months later your paper is still not available online.
a man with a mustache is sitting on a swing in a park
ALT: a man with a mustache is sitting on a swing in a park
media.tenor.com
April 24, 2025 at 2:35 PM
Reposted by Jack Underwood
profsimonfisher.bsky.social
"We established four-part assembloids from human pluripotent stem cells, integrating somatosensory, spinal, thalamic & cortical organoids [...to...] accelerate understanding of sensory circuits & facilitate therapeutic development." Elegant work by the @sergiuppasca.bsky.social lab in @nature.com. 🧪
Human assembloid model of the ascending neural sensory pathway - Nature
A human ascending somatosensory assembloid model was developed, which integrates multiple organoids to simulate the spinothalamic pathway, demonstrating functional connectivity and responsiveness to s...
www.nature.com
April 9, 2025 at 6:05 PM
Reposted by Jack Underwood
leastactionhero.bsky.social
einstein sent this to curie in 1911 when she was being harassed by tabloids. it contains everything you’d want in such a letter:

(1) your haters are trash
(2) you’re a baller, a true queen
(3) i have determined the statistical law of motion of the diatomic molecule in planck’s radiation field 🧪⚛️
Prague, 23 November 1911 Highly esteemed Mrs. Curie, Do not laugh at me for writing you without having anything sensible to say. But I am so enraged by the base manner in which the public is presently daring to concern itself with you!? that I absolutely must give vent to this feeling. However, I am convinced that you consistently despise this rabble, whether it obsequiously lavishes respect on you or whether it attempts to satiate its lust for sensationalism! I am impelled to tell you how much I have come to admire your intellect, your drive, and your honesty, and that I consider myself lucky to have made your personal acquaintance in Brussels. Anyone who does not number among these reptiles is certainly happy, now as before, that we have such personages among us as you, and Langevin(3) too, real people with whom one feels privileged to be in contact. If the rabble continues to occupy itself with you, then simply don't read that hogwash, but rather leave it to the reptile for whom i
June 27, 2024 at 2:17 PM
Reposted by Jack Underwood
martinmckee.bsky.social
🧵 1/11 📚 Our new rapid systematic review, led by @trishgreenhalgh.bsky.social in @bmj.com examines the role of physician associates (PAs) and anaesthetic associates (AAs) in the UK. This is a crucially important question in light of the Leng Review
March 7, 2025 at 5:25 AM
Reposted by Jack Underwood
drrachelclarke.com
Starmer: "You are very, very welcome here in Downing Street. As you heard from the cheers on the street outside, you have full backing across the United Kingdom. We will stand with you and Ukraine for as long as it may take."

Proud to be British tonight.

#SlavaUkrainii 🇺🇦🇺🇦🇺🇦
March 1, 2025 at 8:00 PM
Reposted by Jack Underwood
michelnivard.bsky.social
🚨 This will become a curated list of awesome tools for complex trait genetics, **add yours**! it may become a review in which case those who contribute are invited as co-authors.
GitHub - MichelNivard/awesome-complex-trait-genetics: A list of awesome tools for complex trait genetics.
A list of awesome tools for complex trait genetics. - MichelNivard/awesome-complex-trait-genetics
github.com
November 28, 2024 at 9:21 AM
Reposted by Jack Underwood
jdasmunshi.bsky.social
My first post on Bluesky :) We’re hiring! We’re looking for a postdoc research associate, to come work with us in our national population mental health consortium. If you’re into psych epi, public health & tackling mental health inequities take a look ⏬
www.timeshighereducation.com/unijobs/mini...
Research Associate/Research Fellow in Population Mental Health job with KINGS COLLEGE LONDON | 384309
About us In April 2024, IoPPN, King’s College London led the establishment of a national disseminated population mental health consortium, as part ...
www.timeshighereducation.com
November 22, 2024 at 11:31 PM
Reposted by Jack Underwood
sergiuppasca.bsky.social
Our 2024 CSHL conference on human brain development and stem cell models is in full swing, with over 300 participants!

This year’s event features exciting new discoveries and dynamic discussions, driven largely by the energy & insights of trainees

#Assembloids #Organoids #Brain
#CSHL2024Brain
December 11, 2024 at 4:04 PM
Reposted by Jack Underwood
romanpalace.bsky.social
A lot of people will tell you we're a Roman Palace.

We are in fact a moon-sized super-weapon capable of destroying a planet.

(Better with sound).
December 10, 2024 at 9:16 AM
Reposted by Jack Underwood
awaisaftab.bsky.social
"Why should our entire built environment be optimized to amuse a sliver of one percent of the population, even granting that it amuses them very effectively?"

www.astralcodexten.com/p/book-revie...
Book Review: From Bauhaus To Our House
...
www.astralcodexten.com
December 4, 2024 at 3:42 PM
Reposted by Jack Underwood
welshgasdoc.bsky.social
Looking forward to the biggest shakeup of the NHS since the last one…
"Reorganise to create the illusion of progress. We trained hard, but it seemed that every time we were beginning to work as a team, we would be reorganised. I was to learn later in life that we tend to meet any new situation by reorganizing, and a wonderful method it can be for creating the illusion of progress while producing confusion, inefficiency, and demoralization." Gaius Petronius Arbiter(d. 66 AD) Roman satirist
December 3, 2024 at 1:32 PM
Reposted by Jack Underwood
katewomersley.com
RCPsych needs to move from Twitter to Bluesky! It’s a mental health imperative.
Peers are already here.
December 3, 2024 at 1:00 PM
Reposted by Jack Underwood
ncrenic.bsky.social
“thanks so much for the feedback”
November 30, 2024 at 4:28 PM
Reposted by Jack Underwood
profrobhoward.bsky.social
Disappointing to see a reviewer use a book review to so push his own ideological view of mental illness and mental health services.
www.theguardian.com/books/2024/n...
An Improbable Psychiatrist by Rebecca Lawrence review – doctor turned patient
A brave memoir from a psychiatrist with severe mental illness that describes a failing system from within
www.theguardian.com
November 28, 2024 at 8:15 PM
Reposted by Jack Underwood
ericfauman.bsky.social
I am still obsessing over this bone development paper showing bone replacing cartilage and thinking about how this mirrors the evolutionary innovation of a bony skeleton replacing a cartilage body plan.

Ontogeny recapitulates phylogeny.

www.nature.com/articles/s41...
November 28, 2024 at 7:30 PM
Reposted by Jack Underwood
chrischirp.bsky.social
My latest post on what to expect for the NHS this winter

open.substack.com/pub/christin...

TLDR: looks likely we'll avoid a repeat of disastrous 2022/23 winter, but only by luck 1/6
What is winter looking like for the NHS?
Worrying signs in A&E for October but we are likely to avoid a repeat of the 2022 nightmare winter
open.substack.com
November 27, 2024 at 7:21 AM
Reposted by Jack Underwood
techpriest.bsky.social
Me seeing all the healthcare/psych/MH types appear as followers/mutuals when ~80% of what I post is either unserious/fun or otherwise unrelated to the day job
a man with a mustache is sitting in a red car looking out the window .
Alt: a man with a mustache is sitting in a red car looking out the window .
media.tenor.com
November 26, 2024 at 10:03 PM
Reposted by Jack Underwood
drjanemunro.bsky.social
November 24, 2024 at 5:43 AM
Reposted by Jack Underwood
sergiuppasca.bsky.social
Latest paper in Nature this week: an atlas integrating 36 single-cell datasets spanning 26 protocols for making neural #organoids
Effort led by B. Treutlein, @fabiantheis.bsky.social and @graycamplab.bsky.social
November 21, 2024 at 7:25 PM
Reposted by Jack Underwood
annadamski.bsky.social
This is the live tracker map of Scottish gritter lorries, each with their own hilarious name, like "Grittin' on wae it", "Sled Zepplin" and "Snow bother".

You can find the map here:
experience.arcgis.com/experience/9...
November 20, 2024 at 10:48 PM