Jeremy Shane
@jeremylshane.bsky.social
Working to end chronic disease with Life for Health. Writings at https://hardproblems.substack.com. Formerly Webmd/Medscape, 2U, HealthCentral, Exelon
Reposted by Jeremy Shane
Beyond DOGE in Health
open.substack.com/pub/hardprob...
open.substack.com/pub/hardprob...
Beyond DOGE in Health
The forces at work in Washington and beyond that shape what lies ahead.
open.substack.com
March 29, 2025 at 3:02 PM
Beyond DOGE in Health
open.substack.com/pub/hardprob...
open.substack.com/pub/hardprob...
Reposted by Jeremy Shane
I interviewed Jeffrey Goldberg, editor of @theatlantic.com, at the New Orleans book festival last night
youtu.be/OXkG8Kqxhwk?...
youtu.be/OXkG8Kqxhwk?...
Jeffrey Goldberg and Anne Applebaum discuss the Signal group chat | New Orleans Book Festival
YouTube video by The Atlantic
youtu.be
March 28, 2025 at 11:12 AM
I interviewed Jeffrey Goldberg, editor of @theatlantic.com, at the New Orleans book festival last night
youtu.be/OXkG8Kqxhwk?...
youtu.be/OXkG8Kqxhwk?...
Reposted by Jeremy Shane
If you are one of the #CDC #HHS #FDA #NIH employees who have learned today that your employment is being abruptly ended, we want to hear from you. @altcdc.bsky.social www.statnews.com/2025/02/14/f...
Are you affected by firings at federal health agencies?
Have you been affected by firings at federal health agencies? @statnews would like to hear from you.
www.statnews.com
February 14, 2025 at 6:50 PM
If you are one of the #CDC #HHS #FDA #NIH employees who have learned today that your employment is being abruptly ended, we want to hear from you. @altcdc.bsky.social www.statnews.com/2025/02/14/f...
Fabulous look at debate over seed oils and importance of omega fatty acid balance. Great perspectives and insight!
From Sweetgreen's new "seed oil-free" menu to RFK Jr., the movement to ditch canola, corn, & other vegetable oils has taken off. Read my story on the forces behind the backlash, who's profiting from it, and Americans' broken trust in government and industry:
www.statnews.com/2025/02/12/a...
www.statnews.com/2025/02/12/a...
What MAHA’s crusade against seed oils reveals about flaws in America’s food system
Fears about corn, canola, and similar oils have taken root amid rising concerns about links between industrial food processes and chronic disease.
www.statnews.com
February 12, 2025 at 2:27 PM
Fabulous look at debate over seed oils and importance of omega fatty acid balance. Great perspectives and insight!
Important area of work on LLMs given the understanding gaps we know already exist b/w clinicians and patients in discussing diagnoses and treatments. It’s possible that Q&A with an LLM might help clarify gaps in understanding instead of just stating a conclusion (even with confidence bounds).
Exploring the gap between what LLMs really know vs what people think they know
www.nature.com/articles/s42...
www.nature.com/articles/s42...
What large language models know and what people think they know - Nature Machine Intelligence
Understanding how people perceive and interpret uncertainty from large language models (LLMs) is crucial, as users often overestimate LLM accuracy, especially with default explanations. Steyvers et al...
www.nature.com
January 22, 2025 at 12:20 PM
Important area of work on LLMs given the understanding gaps we know already exist b/w clinicians and patients in discussing diagnoses and treatments. It’s possible that Q&A with an LLM might help clarify gaps in understanding instead of just stating a conclusion (even with confidence bounds).
Reposted by Jeremy Shane
An impressive new issue of Neuron on the science of brain aging with 10 papers on everything from sex differences, role of astrocytes, immune system, waste clearance, autophagy, DNA damage, and rejuvenation cell.com/issue/S0896-...
January 8, 2025 at 3:51 PM
An impressive new issue of Neuron on the science of brain aging with 10 papers on everything from sex differences, role of astrocytes, immune system, waste clearance, autophagy, DNA damage, and rejuvenation cell.com/issue/S0896-...
Reposted by Jeremy Shane
There is huge variation in the strength of member stations. A KQED can lean on our community (and our staff) and survive. Small stations will be in really serious trouble.
public media funding is always under threat — but now Elon Musk is targeting NPR and PBS for budget cuts. @benmullin.bsky.social and I found out how stations are preparing: www.nytimes.com/2024/12/27/b...
NPR and PBS Stations Brace for Funding Battle Under Trump
Republicans in Congress have tried to defund public media for decades. With the help of Elon Musk, could they finally make good on their threat?
www.nytimes.com
December 27, 2024 at 5:14 PM
There is huge variation in the strength of member stations. A KQED can lean on our community (and our staff) and survive. Small stations will be in really serious trouble.
Fantastic summary of the failure of anti-amyloid approaches in Alzheimer’s podcasts.apple.com/us/podcast/t...
The future of Alzheimer’s treatment
Podcast Episode · The Future of Everything · 12/13/2024 · 33m
podcasts.apple.com
December 14, 2024 at 4:55 PM
Fantastic summary of the failure of anti-amyloid approaches in Alzheimer’s podcasts.apple.com/us/podcast/t...
Reposted by Jeremy Shane
Hi! I study how cells form memories. Our lab's most recent study in Nature Commmunications shows that non-neural cells, including kidney cells, can count, detect precise time patterns, and form lasting memories in ways similar to neurons.🧵https://www.nature.com/articles/s41467-024-53922-x
November 23, 2024 at 12:02 AM
Hi! I study how cells form memories. Our lab's most recent study in Nature Commmunications shows that non-neural cells, including kidney cells, can count, detect precise time patterns, and form lasting memories in ways similar to neurons.🧵https://www.nature.com/articles/s41467-024-53922-x
Reposted by Jeremy Shane
What if we used accelerated (biological, epigenetic clock) aging for cancer screening instead of chronological age?
Example for early-inset colon cancer
aacrjournals.org/cancerpreven...
Example for early-inset colon cancer
aacrjournals.org/cancerpreven...
December 10, 2024 at 4:33 PM
What if we used accelerated (biological, epigenetic clock) aging for cancer screening instead of chronological age?
Example for early-inset colon cancer
aacrjournals.org/cancerpreven...
Example for early-inset colon cancer
aacrjournals.org/cancerpreven...
Reposted by Jeremy Shane
Predicting mild cognitive impairment and dementia many years before any symptoms are manifest, a new RAND Corporation report, open-access
www.rand.org/pubs/researc...
www.rand.org/pubs/researc...
December 3, 2024 at 2:31 PM
Predicting mild cognitive impairment and dementia many years before any symptoms are manifest, a new RAND Corporation report, open-access
www.rand.org/pubs/researc...
www.rand.org/pubs/researc...
Reposted by Jeremy Shane
Strong new evidence for T cell exhaustion in myalgic encephalomyelitis (ME/CFS) reflecting chronic viral infection, relevant to #LongCovid, and possible path to treatment candidates
www.pnas.org/doi/epub/10.... @pnas.org
www.pnas.org/doi/epub/10.... @pnas.org
December 2, 2024 at 8:46 PM
Strong new evidence for T cell exhaustion in myalgic encephalomyelitis (ME/CFS) reflecting chronic viral infection, relevant to #LongCovid, and possible path to treatment candidates
www.pnas.org/doi/epub/10.... @pnas.org
www.pnas.org/doi/epub/10.... @pnas.org
Reposted by Jeremy Shane
The HPV vaccine has been recommended in the US since 2006. New study out today shows that cervical cancer deaths in young women in the years that followed have plummeted, decreasing 15% per year from 2013-2015.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Cervical Cancer Mortality Among US Women Younger Than 25 Years
This study examines trends in cervical cancer mortality in US women aged younger than 25 years before and after the introduction of human papillomavirus vaccines.
jamanetwork.com
November 28, 2024 at 2:43 AM
The HPV vaccine has been recommended in the US since 2006. New study out today shows that cervical cancer deaths in young women in the years that followed have plummeted, decreasing 15% per year from 2013-2015.
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...