Javier F Caceres
javierfcaceres.bsky.social
Javier F Caceres
@javierfcaceres.bsky.social
Head of Genome Regulation Section at MRC Human Genetics Unit at the University of Edinburgh. Studying mechanisms of Gene expression and RNA biology. Co-Senior editor at the RNA Journal
Reposted by Javier F Caceres
Very harmonious and inspiring collaboration with Niels Gehring, @volkerboehm.bsky.social and team at Uni Köln, and colleagues at @mdc-berlin.bsky.social . Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome: Molecular Cell www.cell.com/molecular-ce...
Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated human transcriptome
UPF1 depletion inhibits nonsense-mediated mRNA decay (NMD) and stabilizes direct target transcripts within hours. Boehm et al. use conditional protein degradation and advanced transcriptomics to map t...
www.cell.com
September 12, 2025 at 7:26 AM
Reposted by Javier F Caceres
A drug candidate for hard-to-treat cancers, developed by Profs Neil Carragher and Asier Unciti-Broceta at #IGC and licensed to Nuvectis Pharma, has moved to the next stage of clinical trials. Read more here: edin.ac/3UuvJeo
@edinnovations.bsky.social
Life-saving cancer drug takes next step in clinical development | Institute of Genetics and Cancer | Institute of Genetics and Cancer
A drug candidate for hard-to-treat cancers, developed in the Institute of Genetics and Cancer (IGC) and now licensed to Nuvectis Pharma, has moved to the next stage of clinical trials after successful...
edin.ac
August 15, 2025 at 11:34 AM
Reposted by Javier F Caceres
Congratulations to David Tollervey! He received this year's RNA Society Lifetime Achievement in Science Award. @rnasociety.bsky.social
February 11, 2025 at 7:38 AM
Join us in San Diego. A great meeting and also featuring the RNA Journal
Check it out! The RNA Society 2025 Meeting Site is now live! Registration will open in January RNASociety Note the fabulous artwork by former EmoryBCDB student Dr. Carly Lancaster- make your plans now to join us in San Diego May 27-June 1, 2025
November 19, 2024 at 7:27 AM
Reposted by Javier F Caceres
Our paper on a centromere-enriched retroelement is out! link.springer.com/article/10.1... Congratulations to all the authors! Comments and reposts welcome and appreciated 🧬🔬
Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape - Genome Biology
Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements are...
link.springer.com
November 18, 2024 at 5:50 PM
Reposted by Javier F Caceres
Looking for a new home to share all things RNA. That other place was just too crazy. Excited to see so many old RNA friends here on this platform! #RNA
November 18, 2024 at 5:53 PM
Reposted by Javier F Caceres
New EdiRNA events for the new year! Funded by the @RNASociety. Great opportunity to network with other RNA biologists 🧬 (dsRNA included) from Edinburgh and beyond 🚀
Jan 29, 2025
Apr 9, 2025
Jun 11, 2025
Oct TBD, 2025

www.edirna.com/meetings
EVENTS | EdiRNA
ediRNA aims to establish new collaborations, encourage scientific discussion, and enhance interactions between RNA researchers across Edinburgh.
www.edirna.com
November 18, 2024 at 4:37 PM