Jason Yu
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jasonyjc.bsky.social
Jason Yu
@jasonyjc.bsky.social
PhD Student at U of T Biochemistry 🇨🇦 | Rubinstein Lab | Cryo-EM | Mycobacteria

https://scholar.google.com/citations?hl=en&user=PRTcXNsAAAAJ
Reposted by Jason Yu
Does this create an Achilles’ heel, and can you drug it? Turns out: yes.

Congrats to Barbara, Vanisha, Liz, and the rest of the team.

www.nature.com/articles/s41...
Transcription co-inhibition alters drug resistance evolution and enhances Mycobacterium tuberculosis clearance from granulomas - Nature Microbiology
Targeting two distinct steps of the transcription process yields synergistic antibiotics that kill non-replicating Mycobacterium tuberculosis and reduce drug resistance.
www.nature.com
December 3, 2025 at 11:10 AM