See our paper on the unfortunately popular "time-averaged" method in nephrology literature: doi.org/10.2215/CJN....

"Kidney survival times were calculated from baseline...Change in proteinuria was calculated from baseline value to either lowest proteinuria value or time-averaged proteinuria in the 6–12 and 6–24 months periods after baseline." Ie uses future to predict future which can greatly exaggerate effects 😩

Why not?🤔 Seems like an efficient use of resources to answer multiple questions. I don't see a problem

❤️

Morning or mid to late afternoon timing rather than mid-day (lunch time/nap time) 😅

Great you feel supported and kids enjoy participating! And perhaps encouraging for some parents on the fence. For others who don't feel that same support in their cities, with kids afraid of crowds or loud noises, or those just too exhausted, there has to be space for *guilt-free* virtual activism

Hi! 👋 I'm Jarcy Zee, only a pretend adult and pediatric nephrologist, but actually a biostatistician doing lots of GN and other kidney research. Hoping I'm still allowed to hang 😅. First time on #NephJC!

"Robustness of results to assumptions" 😅

(but also the standard error matters too!!)

A 10 mg/kg/day increase in cr generation could lead to a 36 ml/min/1.73m2 decrease in eGFR in a 35yo male or 18 ml/min/1.73m2 decrease in a 8yo female with NO actual change in kidney function! 😳

"Besides age, sex, and weight, important factors that can impact creatinine generation include urine protein in children and kidney function, disease diagnosis, steroid use, and nonsteroid immunosuppressant use in adults."

Yes exactly, the latter was my concern. Didn't see the part about autism but would agree 🙄

Can you clarify? When I first saw the CNN article and started looking into Healthy Babies, Bright Futures, I was skeptical (eg, the report is not written how one would expect scientific research to be written), but could not find much info about them

@super-jrub.bsky.social

Great idea! Reposting with Alt Text.

Borrowed from @sciencelizard.bsky.social so figured I'd also share for others wanting ideas. Here's mine.