Jan Hartmann, M.D.
@janhartmannmd.bsky.social
Bringing Med to MedTech - Physician, Scientist, Photographer, Traveler, Berliner, Immigrant 🇩🇪🇺🇸 - Views=My own, Like/RT≠Endorsement; Haemonetics employee
Liberal or Restrictive Postoperative Transfusion in Cardiac Risk
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Liberal or Restrictive Postoperative Transfusion in Cardiac Risk
This randomized clinical trial tests whether a liberal compared with a restrictive transfusion strategy lowers the risk of a cardiac event 90 days after major vascular or general surgery among patient...
jamanetwork.com
November 9, 2025 at 8:55 AM
Liberal or Restrictive Postoperative Transfusion in Cardiac Risk
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Preparing the Civilian Health Care System for Wartime url: jamanetwork.com/journals/jam...
Preparing the Civilian Health Care System for Wartime
This Viewpoint discusses the need for the US health care system to prepare for war casualties through military and civilian health care collaboration.
jamanetwork.com
October 24, 2025 at 9:46 AM
Preparing the Civilian Health Care System for Wartime url: jamanetwork.com/journals/jam...
Reposted by Jan Hartmann, M.D.
Monoclonal gammopathy of undetermined significance is a common, asymptomatic plasma-cell disorder in older adults that can progress to cancer or systemic illness. Diagnosis warrants follow-up, but treatment is not required unless progression is confirmed. Learn more: nej.md/473uOsj
October 1, 2025 at 9:10 PM
Monoclonal gammopathy of undetermined significance is a common, asymptomatic plasma-cell disorder in older adults that can progress to cancer or systemic illness. Diagnosis warrants follow-up, but treatment is not required unless progression is confirmed. Learn more: nej.md/473uOsj
Reposted by Jan Hartmann, M.D.
“For physician–scientists conducting early clinical trials, the results could best be described as miraculous.” 🧪
2025 #LaskerAward winners M. Welsh, J. González, & P. Negulescu developed life-saving #cysticfibrosis treatments. @nejm.org
#Lasker2025
2025 #LaskerAward winners M. Welsh, J. González, & P. Negulescu developed life-saving #cysticfibrosis treatments. @nejm.org
#Lasker2025
Transformative Research in Cystic Fibrosis | NEJM
Michael Welsh, Jesús González, and Paul Negulescu have won the 2025 Lasker–DeBakey Clinical Medical Research Award for their roles in developing treatments for cystic fibrosis.
www.nejm.org
September 15, 2025 at 2:45 PM
“For physician–scientists conducting early clinical trials, the results could best be described as miraculous.” 🧪
2025 #LaskerAward winners M. Welsh, J. González, & P. Negulescu developed life-saving #cysticfibrosis treatments. @nejm.org
#Lasker2025
2025 #LaskerAward winners M. Welsh, J. González, & P. Negulescu developed life-saving #cysticfibrosis treatments. @nejm.org
#Lasker2025
Reposted by Jan Hartmann, M.D.
“The insights of Görlich, McKnight, and their colleagues are being harnessed in medical research.” 🧪
Read how low-complexity domains of proteins impact human health in @nejm.org
#LaskerAward #Lasker2025 @mpi-nat.bsky.social
#phaseseparation #biophysics
www.nejm.org/doi/full/10....
Read how low-complexity domains of proteins impact human health in @nejm.org
#LaskerAward #Lasker2025 @mpi-nat.bsky.social
#phaseseparation #biophysics
www.nejm.org/doi/full/10....
Surprisingly Complex Assemblies from Low-Complexity Domains | NEJM
Drs. Görlich and McKnight have won the 2025 Albert Lasker Award for Basic Medical
Research for showing that low-complexity domains of proteins lack structure on their
own and yet can form assembled .....
www.nejm.org
September 15, 2025 at 1:51 PM
“The insights of Görlich, McKnight, and their colleagues are being harnessed in medical research.” 🧪
Read how low-complexity domains of proteins impact human health in @nejm.org
#LaskerAward #Lasker2025 @mpi-nat.bsky.social
#phaseseparation #biophysics
www.nejm.org/doi/full/10....
Read how low-complexity domains of proteins impact human health in @nejm.org
#LaskerAward #Lasker2025 @mpi-nat.bsky.social
#phaseseparation #biophysics
www.nejm.org/doi/full/10....
"Impact of Race on Profiles of Platelet Reactivity and Clinical Outcomes in Clopidogrel-Treated Participants"
ascpt.onlinelibrary.wiley.com/doi/abs/10.1...
ascpt.onlinelibrary.wiley.com/doi/abs/10.1...
Impact of Race on Profiles of Platelet Reactivity and Clinical Outcomes in Clopidogrel‐Treated Participants
Black individuals undergoing percutaneous coronary intervention (PCI) experience higher rates of major adverse cardiovascular events (MACE) than non-Black individuals. This study assessed the racial ...
ascpt.onlinelibrary.wiley.com
September 8, 2025 at 3:24 PM
"Impact of Race on Profiles of Platelet Reactivity and Clinical Outcomes in Clopidogrel-Treated Participants"
ascpt.onlinelibrary.wiley.com/doi/abs/10.1...
ascpt.onlinelibrary.wiley.com/doi/abs/10.1...
"Long-Term Anticoagulation Discontinuation After Catheter Ablation for Atrial Fibrillation"
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Discontinuation of Anticoagulant Therapy After Catheter Ablation for Atrial Fibrillation
This randomized clinical trial compares discontinuing vs continuing oral anticoagulant therapy in patients without documented atrial arrhythmia recurrence after catheter ablation for atrial fibrillati...
jamanetwork.com
September 8, 2025 at 3:19 PM
"Long-Term Anticoagulation Discontinuation After Catheter Ablation for Atrial Fibrillation"
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
"Clopidogrel versus aspirin for secondary prevention of coronary artery disease: a systematic review and individual patient data meta-analysis" www.thelancet.com/journals/lan...
Clopidogrel versus aspirin for secondary prevention of coronary artery disease: a systematic review and individual patient data meta-analysis
These findings add to the evidence that clopidogrel monotherapy is superior to aspirin
monotherapy for MACCE prevention with no increase in the risk of bleeding, and support
the preferential use of cl...
www.thelancet.com
September 8, 2025 at 3:18 PM
"Clopidogrel versus aspirin for secondary prevention of coronary artery disease: a systematic review and individual patient data meta-analysis" www.thelancet.com/journals/lan...
Good thing I don't drink coffee...
news.cuanschutz.edu/news-stories...
news.cuanschutz.edu/news-stories...
Study Reveals Caffeine May Undermine Blood Transfusion Effectiveness
Study Reveals Caffeine May Undermine Blood Transfusion Effectiveness
news.cuanschutz.edu
September 8, 2025 at 12:31 PM
Good thing I don't drink coffee...
news.cuanschutz.edu/news-stories...
news.cuanschutz.edu/news-stories...
Reposted by Jan Hartmann, M.D.
In patients with heparin-induced thrombocytopenia, pathogenic antibodies were found to be monoclonal, which challenges previous views of HIT as a polyclonal disorder and suggests new avenues for diagnosis and treatment. Full study results: nej.md/4pkaYAq
#MedSky #CardioSky
#MedSky #CardioSky
September 3, 2025 at 10:00 PM
In patients with heparin-induced thrombocytopenia, pathogenic antibodies were found to be monoclonal, which challenges previous views of HIT as a polyclonal disorder and suggests new avenues for diagnosis and treatment. Full study results: nej.md/4pkaYAq
#MedSky #CardioSky
#MedSky #CardioSky
Rainbow over Sandy Bay – Rockport, MA 🌈
August 30, 2025 at 1:52 AM
Rainbow over Sandy Bay – Rockport, MA 🌈
Sex differences in dual antiplatelet therapy de-escalation strategies after percutaneous coronary intervention: a network meta-analysis url: academic.oup.com/eurheartj/ar...
Sex differences in dual antiplatelet therapy de-escalation strategies after percutaneous coronary intervention: a network meta-analysis
AbstractBackground and Aims. Dual antiplatelet therapy (DAPT) de-escalation strategies improve outcomes after percutaneous coronary intervention (PCI) comp
academic.oup.com
August 6, 2025 at 3:07 PM
Sex differences in dual antiplatelet therapy de-escalation strategies after percutaneous coronary intervention: a network meta-analysis url: academic.oup.com/eurheartj/ar...
A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery | New England Journal of Medicine www.nejm.org/doi/full/10....
A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery | NEJM
Patients undergoing cardiac surgery often receive red-cell transfusions, along with
the associated risks and costs. Early intraoperative normovolemic hemodilution (i.e.,
acute normovolemic hemodilu...
www.nejm.org
August 1, 2025 at 2:21 PM
A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery | New England Journal of Medicine www.nejm.org/doi/full/10....
Reposted by Jan Hartmann, M.D.
In the BATURA phase 3b trial, as-needed albuterol–budesonide resulted in a lower risk of severe asthma exacerbation than as-needed albuterol among participants with disease that was uncontrolled despite treatment for mild asthma. Full trial results and Research Summary: nej.md/43uVpwK
July 13, 2025 at 7:01 PM
In the BATURA phase 3b trial, as-needed albuterol–budesonide resulted in a lower risk of severe asthma exacerbation than as-needed albuterol among participants with disease that was uncontrolled despite treatment for mild asthma. Full trial results and Research Summary: nej.md/43uVpwK
Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation | New England Journal of Medicine www.nejm.org/doi/abs/10.1...
Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation | NEJM
Transcatheter aortic-valve implantation (TAVI) is associated with procedure-related
stroke. Cerebral embolic protection (CEP) devices may reduce embolization to the cerebral
circulation and hence t...
www.nejm.org
July 11, 2025 at 4:04 PM
Routine Cerebral Embolic Protection during Transcatheter Aortic-Valve Implantation | New England Journal of Medicine www.nejm.org/doi/abs/10.1...
Last night at #ISTH2025, we honored a gentle giant—Dr. Hau Kwaan, Professor Emeritus at Northwestern. A true #Fibrinolysis pioneer with 400+ articles since the 1950s—still contributing posters in his 90s. Thanks, Mark Walsh, for a moving laudatio.
@isth.org
www.linkedin.com/posts/janhar...
@isth.org
www.linkedin.com/posts/janhar...
Later last night at #ISTH2025, we had the privilege of honoring a gentle giant of the field—Dr. | Jan Hartmann, M.D.
Later last night at #ISTH2025, we had the privilege of honoring a gentle giant of the field—Dr. Hau Kwaan, MD, PhD, FRCP, FACP, Professor Emeritus at Northwestern University - The Feinberg School of M...
www.linkedin.com
June 22, 2025 at 11:43 AM
Last night at #ISTH2025, we honored a gentle giant—Dr. Hau Kwaan, Professor Emeritus at Northwestern. A true #Fibrinolysis pioneer with 400+ articles since the 1950s—still contributing posters in his 90s. Thanks, Mark Walsh, for a moving laudatio.
@isth.org
www.linkedin.com/posts/janhar...
@isth.org
www.linkedin.com/posts/janhar...
Reposted by Jan Hartmann, M.D.
It’s Code Red for Vaccines
The number of changes to vaccine policy is dizzying & RFK Jr is just getting started!
Dissolving the group of experts that drive policy is declaring war on “what was”
I write in @nytimes.com about what is and is not working
www.nytimes.com/2025/06/11/o...
The number of changes to vaccine policy is dizzying & RFK Jr is just getting started!
Dissolving the group of experts that drive policy is declaring war on “what was”
I write in @nytimes.com about what is and is not working
www.nytimes.com/2025/06/11/o...
Opinion | It’s Code Red for Vaccines in America (Gift Article)
How to make sense of all the vaccine policy changes.
www.nytimes.com
June 11, 2025 at 12:46 PM
It’s Code Red for Vaccines
The number of changes to vaccine policy is dizzying & RFK Jr is just getting started!
Dissolving the group of experts that drive policy is declaring war on “what was”
I write in @nytimes.com about what is and is not working
www.nytimes.com/2025/06/11/o...
The number of changes to vaccine policy is dizzying & RFK Jr is just getting started!
Dissolving the group of experts that drive policy is declaring war on “what was”
I write in @nytimes.com about what is and is not working
www.nytimes.com/2025/06/11/o...
Reposted by Jan Hartmann, M.D.
This tiny device can shrink dangerous blood clots. It’s called the ‘milli-spinner’ and its invention was partly an accident…
June 10, 2025 at 10:39 AM
This tiny device can shrink dangerous blood clots. It’s called the ‘milli-spinner’ and its invention was partly an accident…
2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP url:https://academic.oup.com/ejcts/article/67/5/ezae352/7815985
June 9, 2025 at 2:01 AM
2024 EACTS/EACTAIC Guidelines on patient blood management in adult cardiac surgery in collaboration with EBCP url:https://academic.oup.com/ejcts/article/67/5/ezae352/7815985
June 8, 2025 at 5:03 PM
