@janfabio.bsky.social
Reposted
🧬 1/ Heterochromatin protein 1 (HP1) still surprises us after all these years: It simply sticks to chromatin when pericentric heterochromatin domains – the chromocenters – are activated in mouse fibroblasts and acts as a local rather than global repressor. New preprint: doi.org/10.1101/2024...
December 13, 2024 at 1:47 PM
🧬 1/ Heterochromatin protein 1 (HP1) still surprises us after all these years: It simply sticks to chromatin when pericentric heterochromatin domains – the chromocenters – are activated in mouse fibroblasts and acts as a local rather than global repressor. New preprint: doi.org/10.1101/2024...
Reposted
Holistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1
Holistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1
Tissue macrophages are crucial for organ development and homeostasis, yet the developmental routes l
www.biorxiv.org
November 30, 2024 at 9:30 PM
Holistic genetic barcoding reveals a lineage tree of tissue macrophage development https://www.biorxiv.org/content/10.1101/2024.11.29.625985v1
Reposted
Let the new spatial barcoding era begin!
🚨𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 𝐢𝐬 𝐡𝐞𝐫𝐞!
New preprint by my colleague @dpostrach.bsky.social:
𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 uses 𝐮𝐩 𝐭𝐨 𝟓𝟏𝟐 𝐜𝐨𝐥𝐨𝐫𝐬 𝐭𝐨 𝐭𝐫𝐚𝐜𝐞 𝐜𝐥𝐨𝐧𝐞𝐬 𝐢𝐧 𝐬𝐢𝐭𝐮 as they grow, expand and travel. And cheap readout using IBEX.
Can't wait to see all the fields that will profit from this tool!
🚨𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 𝐢𝐬 𝐡𝐞𝐫𝐞!
New preprint by my colleague @dpostrach.bsky.social:
𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 uses 𝐮𝐩 𝐭𝐨 𝟓𝟏𝟐 𝐜𝐨𝐥𝐨𝐫𝐬 𝐭𝐨 𝐭𝐫𝐚𝐜𝐞 𝐜𝐥𝐨𝐧𝐞𝐬 𝐢𝐧 𝐬𝐢𝐭𝐮 as they grow, expand and travel. And cheap readout using IBEX.
Can't wait to see all the fields that will profit from this tool!
Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping https://www.biorxiv.org/content/10.1101/2024.11.20.624484v1
Polytope: High-resolution epitope barcoding for in vivo spatial fate-mapping https://www.biorxiv.org/content/10.1101/2024.11.20.624484v1
Tracing the fate of individual cells and their progeny remains a challenging task. While imaging-bas
www.biorxiv.org
December 1, 2024 at 10:45 PM
Let the new spatial barcoding era begin!
🚨𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 𝐢𝐬 𝐡𝐞𝐫𝐞!
New preprint by my colleague @dpostrach.bsky.social:
𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 uses 𝐮𝐩 𝐭𝐨 𝟓𝟏𝟐 𝐜𝐨𝐥𝐨𝐫𝐬 𝐭𝐨 𝐭𝐫𝐚𝐜𝐞 𝐜𝐥𝐨𝐧𝐞𝐬 𝐢𝐧 𝐬𝐢𝐭𝐮 as they grow, expand and travel. And cheap readout using IBEX.
Can't wait to see all the fields that will profit from this tool!
🚨𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 𝐢𝐬 𝐡𝐞𝐫𝐞!
New preprint by my colleague @dpostrach.bsky.social:
𝐏𝐨𝐥𝐲𝐭𝐨𝐩𝐞 uses 𝐮𝐩 𝐭𝐨 𝟓𝟏𝟐 𝐜𝐨𝐥𝐨𝐫𝐬 𝐭𝐨 𝐭𝐫𝐚𝐜𝐞 𝐜𝐥𝐨𝐧𝐞𝐬 𝐢𝐧 𝐬𝐢𝐭𝐮 as they grow, expand and travel. And cheap readout using IBEX.
Can't wait to see all the fields that will profit from this tool!
Reposted
HP1 binding creates a local barrier against transcription activation and persists during chromatin decondensation https://www.biorxiv.org/content/10.1101/2024.12.09.627308v1
December 11, 2024 at 10:30 AM
HP1 binding creates a local barrier against transcription activation and persists during chromatin decondensation https://www.biorxiv.org/content/10.1101/2024.12.09.627308v1