Jack Tierney
jackatierney.bsky.social
Jack Tierney
@jackatierney.bsky.social
Bioinformatician @ EMBL-EBI - Ensembl Genebuild

Formerly:

Post Doctoral Researcher @ UCC, Ireland

RNA Biology, Translation, Ribo-Seq

Bioinformatic Method Development & Research Infrastructure
And with Lepidoptober coming fast...
September 5, 2025 at 6:55 PM
In 1891, Stoney coined electron as the unit of electric charge borrowing the neuter Greek suffix -on. Others followed with proton, neutron cementing “-on” as the mark of a fundamental unit. In the 50s we got cistron, codon as the units of gene expression were defined and then exon, intron, translon
September 2, 2025 at 8:13 PM
Writing this short correspondence sparked great semantic discussions with leaders of a diverse set of fields and particularly among the primary instigators of this initiative (myself, Michał Świrski, Eivind Valen and Pasha Baranov)

Full Text:
rdcu.be/eDnOj
Translon: a single term for translated regions
Nature Methods - Translon: a single term for translated regions
rdcu.be
September 1, 2025 at 3:37 PM
Just as Walter Gilbert's exon/intron terminology ('Why genes in pieces?', Nature 1978) gave us language to discuss and understand gene structure, 'Translon' aims to provide vocabulary to better conceptualise the pervasive, largely still enigmatic, translation revealed by Ribo-Seq
September 1, 2025 at 3:37 PM