Jonathan Mitchell
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j-a-mitchell.bsky.social
Jonathan Mitchell
@j-a-mitchell.bsky.social
Associate Professor of Pediatrics at UPenn and CHOP | wearables | data science | sleep | nutrition
Reposted by Jonathan Mitchell
Just out: Led by @j-a-mitchell.bsky.social and Babette Zemel "gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood" @asbmr.bsky.social. Funded by our #NICHD award R01 HD100406. @chopresearch.bsky.social @penngenetics.bsky.social

academic.oup.com/jbmr/article...
The gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood
Abstract. The polygenic risk score genetic quantitative ultrasound speed of sound (gSOS) was developed using machine learning algorithms in adults of Europ
academic.oup.com
October 14, 2025 at 1:42 PM
Reposted by Jonathan Mitchell
Dreaming of a dataset that tracks mood, sleep & activity to better understand affective instability (AI)…AND paired with advanced MRI? 🤯
Check out our new bioRxiv preprint for a 13–23 y/o community sample (n=10 and growing!) with multi-echo fMRI, EMA & actigraphy: www.biorxiv.org/content/10.1...
May 6, 2025 at 3:32 PM
Reposted by Jonathan Mitchell
PREPRINT: Led by @j-a-mitchell.bsky.social & Babette Zemel, we show higher gSOS polygenic score associated with higher pediatric aBMD 🦴 & lower fracture risk @chopresearch.bsky.social . gSOS previously developed with ML on adults by @brent-richards.bsky.social team

www.medrxiv.org/content/10.1...
The gSOS Polygenic Score is Associated with Bone Density and Fracture Risk in Childhood
The polygenic risk score genetic quantitative ultrasound speed of sound (gSOS) was developed using machine learning algorithms in adults of European ancestry and associates with reduced odds of fractu...
www.medrxiv.org
April 24, 2025 at 12:16 PM