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High-quality, topflight, and clinically impactful basic and translational research representative of all biomedical specialties and physician-scientists: https://insight.jci.org/
A high percentage of neonatal seizures resist treatment
Joseph Glykys & team show recurrent neonatal seizures increases tonic inhibition through extrasynaptic GABAA receptors and respond to delta subunit selective GABAergic enhancers in mouse models: insight.jci.org/articles/vie...
Joseph Glykys & team show recurrent neonatal seizures increases tonic inhibition through extrasynaptic GABAA receptors and respond to delta subunit selective GABAergic enhancers in mouse models: insight.jci.org/articles/vie...
November 11, 2025 at 2:03 PM
A high percentage of neonatal seizures resist treatment
Joseph Glykys & team show recurrent neonatal seizures increases tonic inhibition through extrasynaptic GABAA receptors and respond to delta subunit selective GABAergic enhancers in mouse models: insight.jci.org/articles/vie...
Joseph Glykys & team show recurrent neonatal seizures increases tonic inhibition through extrasynaptic GABAA receptors and respond to delta subunit selective GABAergic enhancers in mouse models: insight.jci.org/articles/vie...
Recently, a rare pediatric case revealed a role for Site1-protease in development and lipid metabolism.
Lijun Xia & team generated mouse models, discovering S1P/SREBP2-mediated cholesterol biosynthesis is necessary for lymphatic vascular development: insight.jci.org/articles/vie...
Lijun Xia & team generated mouse models, discovering S1P/SREBP2-mediated cholesterol biosynthesis is necessary for lymphatic vascular development: insight.jci.org/articles/vie...
November 5, 2025 at 2:03 PM
Recently, a rare pediatric case revealed a role for Site1-protease in development and lipid metabolism.
Lijun Xia & team generated mouse models, discovering S1P/SREBP2-mediated cholesterol biosynthesis is necessary for lymphatic vascular development: insight.jci.org/articles/vie...
Lijun Xia & team generated mouse models, discovering S1P/SREBP2-mediated cholesterol biosynthesis is necessary for lymphatic vascular development: insight.jci.org/articles/vie...
A potential new target in inflammatory bowel disease!
Agnieszka K. Czopik & team reveal the microRNA miR-147 protects intestinal integrity during inflammation: insight.jci.org/articles/vie...
Agnieszka K. Czopik & team reveal the microRNA miR-147 protects intestinal integrity during inflammation: insight.jci.org/articles/vie...
October 31, 2025 at 4:16 PM
A potential new target in inflammatory bowel disease!
Agnieszka K. Czopik & team reveal the microRNA miR-147 protects intestinal integrity during inflammation: insight.jci.org/articles/vie...
Agnieszka K. Czopik & team reveal the microRNA miR-147 protects intestinal integrity during inflammation: insight.jci.org/articles/vie...