Inserm U1034 - Biology of Cardiovascular Diseases
insermu1034.bsky.social
Inserm U1034 - Biology of Cardiovascular Diseases
@insermu1034.bsky.social
#CardiovascularDisease #Endothelium #Thrombosis #SmallVesselDisease #NeurovascularUnit
Thesis defense season is open ! 🎓
Congratulations to Marin Lahouati, who brillantly defended his PhD last week ! 🎉 We wish you all the best for your next career chapter !
September 24, 2025 at 7:37 AM
Last week, #InsermU1034 presented their work at the #PrintempsdelaCardiologie at St Malo ! A special congratulation to Célia Bourguignon, PhD student, who won the poster price ! Many thanks to the organizers and speakers ! #GRRC #SFCardio
May 28, 2025 at 7:48 AM
Reposted by Inserm U1034 - Biology of Cardiovascular Diseases
Our review on the treatment of thrombotic complications in patients with myeloproliferative neoplasms has just been published in the latest issue of Blood, in a “how I treat” series on MPN.
April 23, 2025 at 4:31 PM
Last week, @candicechaps.bsky.social and @margauxlaisne.bsky.social presented their work in #EMBOastrocytes2025 in Venice. Many thanks to @embo.org for the great organization and speakers for all these inspiring talks !
April 25, 2025 at 12:47 PM
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[Publication] Dr. Foussard and Dr Renault latest publication in @biomedcentral.bsky.social shows that ICAM1 blockade improves ischemic muscle reperfusion in diabetic mice.
cardiab.biomedcentral.com/articles/10....
ICAM1 blockade improves ischemic muscle reperfusion in diabetic mice - Cardiovascular Diabetology
Background Chronic Limb-Threatening Ischemia (CLTI) represents the most advanced stage of Peripheral Artery Disease (PAD) and is associated with dire prognosis, characterized by a substantial risk of ...
cardiab.biomedcentral.com
April 25, 2025 at 12:09 PM
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[Publication] Happy to share @candicechaps.bsky.social and Dr Mora latest publication in @biomedcentral.bsky.social. They demonstrate that Dll4-Notch1 pathway controls astrogliosis in neuroinflammatory context such as MS. jneuroinflammation.biomedcentral.com/articles/10....
Astrocytic DLL4-NOTCH1 signaling pathway promotes neuroinflammation via the IL-6-STAT3 axis - Journal of Neuroinflammation
Under neuroinflammatory conditions, astrocytes acquire a reactive phenotype that drives acute inflammatory injury as well as chronic neurodegeneration. We hypothesized that astrocytic Delta-like 4 (DL...
jneuroinflammation.biomedcentral.com
April 25, 2025 at 12:05 PM
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[Publication] Explore our latest publication on DNases and NETs in COVID-19. Investigating DNase activity in thrombo-inflammation may identify clinical scenarios for DNase administration, potentially averting clinical deterioration !
translational-medicine.biomedcentral.com/articles/10....
Impaired balance between neutrophil extracellular trap formation and degradation by DNases in COVID-19 disease - Journal of Translational Medicine
Background Thrombo-inflammation and neutrophil extracellular traps (NETs) are exacerbated in severe cases of COVID-19, potentially contributing to disease exacerbation. However, the mechanisms underpi...
translational-medicine.biomedcentral.com
April 25, 2025 at 12:02 PM
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[Publication] Dr @pauline-bougaran.bsky.social, Dr Bats and Pr Dufourcq published they last work on «ROR2/PCP a New Pathway Controlling Endothelial Cell Polarity Under Flow Conditions» in @ahajournals.bsky.social.
www.ahajournals.org/doi/10.1161/...
American Heart Association Journals
www.ahajournals.org
April 25, 2025 at 12:00 PM
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[Publication] Happy to share Dr Renault, Dr
Rouault and Dr @sarahguimbal.bsky.social publication in which they demonstrated that small vessels thrombosis may participate in the pathophysiology of #HFpEF in @ahajournals.bsky.social 🫀
www.ahajournals.org/doi/10.1161/...
Thrombosis in the Coronary Microvasculature Impairs Cardiac Relaxation and Induces Diastolic Dysfunction | Arteriosclerosis, Thrombosis, and Vascular Biology
BACKGROUND: Heart failure with preserved ejection fraction is proposed to be caused by endothelial dysfunction in cardiac microvessels. Our goal was to identify molecular and cellular mechanisms under...
www.ahajournals.org
April 25, 2025 at 11:55 AM
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[Publication] Thrilled to share that our article about the role of NETs in myeloproliferative neoplasms-associated thrombosis has been published in @jthjournal.bsky.social !
www.jthjournal.org/article/S153...
Platelets and neutrophils cooperate to induce increased neutrophil extracellular trap formation in JAK2V617F myeloproliferative neoplasms
Neutrophils participate in the pathogenesis of thrombosis through the formation of neutrophil extracellular traps (NETs). Thrombosis is the main cause of morbidity and mortality in patients with myelo...
www.jthjournal.org
April 25, 2025 at 11:52 AM
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[Publication] Happy to share Dr Renault and
Dr Cornuault's new publication in which they demonstrated that #cardiacpericytes are essential for maintaining #cardiacfunction, directly modulating cardiomyocyte properties and preventing cardiac inflammation. www.ahajournals.org/doi/full/10....
Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction | Journal of the American Heart Association
www.ahajournals.org
April 25, 2025 at 11:49 AM