Institute of Neurodegenerative Diseases
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imn-bordeaux.bsky.social
Institute of Neurodegenerative Diseases
@imn-bordeaux.bsky.social
IMN combines fundamental, preclinical and clinical research in neurosciences with the aim of develop new therapeutic approaches for neurodegenerative diseases 🧠
📰 Phenotypic characterization of an Atp13a2 knockout rat model of Parkinson’s disease
✒️ By R Kinet, ML Arotçarena, E Doudnikoff, A. Lovisotto, ML Thiolat, N Dutheil, C Mazzocco, F Georges, E Bezard, PO Fernagut, B Dehay and al. published in NPJ Parkinson Disease
www.nature.com/articles/s41...
Phenotypic characterization of an Atp13a2 knockout rat model of Parkinson’s disease - npj Parkinson's Disease
npj Parkinson's Disease - Phenotypic characterization of an Atp13a2 knockout rat model of Parkinson’s disease
www.nature.com
November 19, 2025 at 12:47 PM
@cedricbrun.bsky.social and Thomas Boraud, coorganise with Serge Ahmed and Thomas pradeux, "The Impact of Philosophical Thinking on Today's Neuroscience"
📅 November 24th-25th, University of Bordeaux, IBGC
🎟️ Mandatory Registration
📍 Details and registration : philinbiomed.cnrs.fr/event/philos...
Conference: The Impact of philosophical thinking on today’s neuroscience – philinbiomed
Please feel free to circulate this announcement to all the persons who may be interested.
philinbiomed.cnrs.fr
November 13, 2025 at 1:14 PM
Reposted by Institute of Neurodegenerative Diseases
🔬 Des chercheurs, notamment de l’Institut des maladies neurodégénératives @imn-bordeaux.bsky.social , montrent qu’un modèle de fibrille d’alpha-synucléine fabriqué in vitro peut se répliquer et se propager dans le cerveau de souris (1/2)
Quand une fibrille synthétique s’auto-réplique dans le cerveau | CNRS Biologie
L’atrophie multisystématisée (MSA) est une maladie neurodégénérative rare et incurable marquée par la présence d’inclusions intracellulaires faites de f
www.insb.cnrs.fr
November 12, 2025 at 5:00 PM
Reposted by Institute of Neurodegenerative Diseases
OFFRE D'EMPLOI - Assistant·e Ingénieure en expérimentation animale
💫

Le PIV-EXPE recrute pour rejoindre son équipe engagée et passionnée, au service de la recherche en neurosciences fondamentales et translationnelles.

👉 Pour plus d'infos : imn.u-bordeaux.fr/.../assistan...
Assistant·e Ingénieure en expérimentation animale × IMN
Institut des Maladies Neurodégénératives
imn.u-bordeaux.fr
October 31, 2025 at 8:48 AM
A l'occasion de la Semaine de l'Open Access et de la Science Ouverte 2025, des webinaires en ligne sont organisés toute la semaine !
👥 Ils visent à valoriser et promouvoir les pratiques de recherche ouverte, accessible et collaborative.

www.bordeaux-neurocampus.fr/event/semain...
Semaine de l’Open Access et de la Science Ouverte 2025 - Bordeaux Neurocampus
A l'initiative de l'Université de Bordeaux
www.bordeaux-neurocampus.fr
October 21, 2025 at 1:19 PM
Hack1robo 2025 - retour sur évènement 🤖
Le hackathon qui fusionne IA, Robotique, Sciences Cognitives et Arts 🎨🤖🧠

@sudouest.fr était présent: www.sudouest.fr/gironde/bord...

Bravo au comité d'organisation pour cette superbe édition : X. Hinaut, L. Fontaine, Y. Bendi-Ouis, C. Mercier et A. Gillig 🙌
« C’est un marathon de la bidouille » : à Bordeaux, quand l’IA rencontre les arts et la robotique
Ce dimanche, à la Station Marne, neuf équipes présenteront leurs prototypes élaborés durant 48 heures. Des projets qui peuvent parfois aller bien au-delà de la bonne idée
www.sudouest.fr
October 20, 2025 at 1:49 PM
🗣️ Soirée AVC: prévention, science et échanges grand public

Qu’est-ce qu’un AVC? À quoi sert la recherche en imagerie pour la prévention des AVC?

📅 29/10, 18h
📍 Café des Sciences, Cap Sciences
🎤 @micheltds.bsky.social, S. Olindo, R. Benazzouz et C. Sanchez-Cortes
👉 imn.u-bordeaux.fr/en/events/so...
Soirée AVC : prévention, science et échanges – Mini-talks grand public × IMN
Institut des Maladies Neurodégénératives
imn.u-bordeaux.fr
October 20, 2025 at 12:52 PM
Les Entretiens Alzheimer 2025 🧩
Que vous soyez aidants, patients ou curieux, venez en apprendre + sur la maladie d'Alzheimer
🗓️ Lundi 13 octobre, 14h-17h
📍 Palais de la Bourse, Bordeaux
🗣️ @vincentplanche.bsky.social et autres professionnels de santé

www.bordeaux-neurocampus.fr/event/les-en...
Les entretiens alzheimer - 8ème édition, Bordeaux - Bordeaux Neurocampus
Venez assister à la 8ème édition des entretiens Alzheimer
www.bordeaux-neurocampus.fr
October 8, 2025 at 12:16 PM
New comment in @nature.com by @nicolasrougier.bsky.social and al.:
Stop treating code like an afterthought: record, share and value it.
Scientists, research institutions, funders, libraries and publishers must all improve software practices.

👉 For more details : www.nature.com/articles/d41...
Stop treating code like an afterthought: record, share and value it
Scientists, research institutions, funders, libraries and publishers must all improve software practices.
www.nature.com
October 7, 2025 at 12:10 PM
How can we improve the differential diagnosis of neurodegenerative diseases with AI-enhanced MRI analyses? How can we make the interpretation of results easier for clinicians?
📰 New article from @vincentplanche.bsky.social and al.

For more details : alzres.biomedcentral.com/articles/10....
petBrain: a new pipeline for amyloid, Tau tangles and neurodegeneration quantification using PET and MRI - Alzheimer's Research & Therapy
Introduction Quantification of amyloid plaques (A), neurofibrillary tangles (T2), and neurodegeneration (N) using PET and MRI is critical for Alzheimer’s disease (AD) diagnosis and prognosis. Existing pipelines face limitations regarding processing time, tracer variability handling, and multimodal integration. Methods We developed petBrain, a novel end-to-end processing pipeline for amyloid-PET, tau-PET, and structural MRI. It leverages deep learning-based segmentation, standardized biomarker quantification (Centiloid, CenTauR, HAVAs), and simultaneous estimation of A, T2, and N biomarkers. It is implemented in a web-based format, requiring no local computational infrastructure and software usage knowledge. Results petBrain provides reliable, rapid quantification with results comparable to existing pipelines for A and T2, showing strong concordance with data processed in ADNI databases. The staging and quantification of A/T2/N by petBrain demonstrated good agreements with CSF/plasma biomarkers, clinical status and cognitive performance. Discussion petBrain represents a powerful open platform for standardized AD biomarker analysis, facilitating clinical research applications.
alzres.biomedcentral.com
October 2, 2025 at 1:29 PM
Reposted by Institute of Neurodegenerative Diseases
🏆 Pascal Fossat @imn-bordeaux.bsky.social , est lauréat 2025 du fonds franco-canadien pour travailler sur les récepteurs de la sérotonine spinale comme nouvelles cibles thérapeutiques potentielles pour la douleur :
Pascal Fossat, lauréat du fonds franco-canadien pour la recherche - Bordeaux Neurocampus
Financement de l'ambassade de France au Canada
www.bordeaux-neurocampus.fr
September 11, 2025 at 4:00 PM
🎉 NEW TEAM IN THE LAB!
@agnesnadjar.bsky.social set up her own team - Neuroimmunology lab, to study how the immune system and the central nervous system communicate, both under healthy conditions and during disease !

👉 For more details : www.bordeaux-neurocampus.fr/en/team/neur...
Neuroimmunology lab - Bordeaux Neurocampus
Our team studies how the immune system and the central nervous system communicate, both under healthy conditions and during disease. We are particularly interested in how this two-way “neuroimmune” di...
www.bordeaux-neurocampus.fr
September 8, 2025 at 1:29 PM
Reposted by Institute of Neurodegenerative Diseases
📰 L’atrophie multi-systématisée est une pathologie neurodégénérative rare, proche de la maladie de Parkinson. Quels sont les signes cliniques ? Comment la diagnostiquer, la prendre en charge ? Le point dans Femme Actuelle avec Wassilios Meissner @imn-bordeaux.bsky.social : www.femmeactuelle.fr...
Atrophie multi-systématisée : diagnostic, prise en charge et pronostic de cette maladie proche de Parkinson
L’atrophie multi-systématisée est une pathologie neurodégénérative rare, proche de la maladie de Parkinson. Quels sont les signes cliniques ? Comment la diagnostiquer et la prendre en charge ? Le point avec le Pr Wassilios Meissner, chef du service de neurologie des maladies neurodégénératives au CHU de Bordeaux, et coordinateur national du centre de référence de l’AMS.
www.femmeactuelle.fr
July 23, 2025 at 7:01 AM
Reposted by Institute of Neurodegenerative Diseases
August #ImageOfTheMonth is from L.Congiu from
@imn-bordeaux.bsky.social. This is a 3D reconstruction of a CD68-positive particles (white) within the cell body of microglia cells (Red) in the mouse cortex. The confocal Z-stack was processed with Imaris software.
August 7, 2025 at 6:56 PM
Reposted by Institute of Neurodegenerative Diseases
September #ImageOfTheMonth is from @rkinet.bsky.social from @imn-bordeaux.bsky.social
This is a maximum projection of a confocal image of a microglia cell (blue) and its nucleus (red), internalising multiple nanoparticles (yellow), one day after supranigral injection in C57B6-J mouse
September 8, 2025 at 9:09 AM
Multiple System Atrophy is a rare neurodegenerative disorder closely related to Parkinson's disease.
🔎 But what are its clinical signs? How is it diagnosed and managed?
🕵 Here's an update from Pr. Wassilios Meissner
🗞️ Article : www.femmeactuelle.fr/sante/sante-...
Atrophie multi-systématisée : diagnostic, prise en charge et pronostic de cette maladie proche de Parkinson
L’atrophie multi-systématisée est une pathologie neurodégénérative rare, proche de la maladie de Parkinson. Quels sont les signes cliniques ? Comment la diagnostiquer et la prendre en charge ? Le point avec le Pr Wassilios Meissner, chef du service de neurologie des maladies neurodégénératives au CHU de Bordeaux, et coordinateur national du centre de référence de l’AMS.
www.femmeactuelle.fr
July 16, 2025 at 1:14 PM
OHBM is coming to Bordeaux in 2026 🥳
📍 Advance the understanding of the anatomical and functional organization of the human brain, and promote its medical and societal applications 🧠
📅 June 14-18th, 2026
👥 Co-organised by @micheltds.bsky.social and C. Foulon
🎥 produced by Koffi Productions 🥖 🇫🇷 🍷
OHBM 2026 Bordeaux
YouTube video by Clinical Neuroanatomy Seminars
www.youtube.com
July 2, 2025 at 9:26 AM
🎧 Sia Gullapalli, student from USA, has created a podcast called ‘Her Path to Success’ to celebrate the journeys of women who are making waves in their fields.

👩‍🔬 It was in this context that she interviewed @cglangetas.bsky.social about her work 🔬

📍 Episode : open.spotify.com/episode/2Pct...
Brains, Breakthroughs, and Bordeaux: Dr. Glangetas on the Future of Neuroscience
Her Path to Success · Episode
open.spotify.com
June 26, 2025 at 8:59 AM
📰 "Striatal interdependencies in focal seizures: Insights from stereoelectroencephalographic functional connectivity analysis" 🧠

✒️ An article by Léa Chibany, Elena Nicollin, Edouard Courtin, Jérôme Aupy and al.
Published in Wiley

📍 For more : onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
June 20, 2025 at 8:57 AM
"Differential pathological dynamics triggered by distinct Parkinson patient–derived α-synuclein extracts in nonhuman primates", by Rémi Kinet and al. 🧠

Published in Science Advances.

For more : www.science.org/doi/10.1126/...

@neurobordeaux.bsky.social @benjamindehay.bsky.social
Differential pathological dynamics triggered by distinct Parkinson patient–derived α-synuclein extracts in nonhuman primates
Distinct α-synuclein assemblies trigger distinct neurotoxic cellular pathways.
www.science.org
June 19, 2025 at 8:35 AM
📢 Congrés : 7èmes Journées de Neurophysiologie Clinique 🧑‍⚕️
🗣️ Organisé par N. Delgado-Piccoli, D. Guehl, JA. Micoulaud Franchi, P. Burbaud, I. Ghorayeb, V. Michel, J. Aupy et E. Courtin
📅 1-3 Juillet 2025
📍 Bordeaux France
🎟️ Inscription obligatoire

+ d'infos: secure.key4events.com/key4register...
secure.key4events.com
June 18, 2025 at 12:46 PM
Reposted by Institute of Neurodegenerative Diseases
Mind the deadlines for our 11th international conference "BrainBody - Exploring bidirectional crosstalk between the central nervous system and the body"!
⏳ Early bird registration and abstract submission deadline: July 1st!
📅 1-3 October 2025
📍 Bordeaux, France

👉 brainconf.u-bordeaux.fr/en/
June 16, 2025 at 9:59 AM
Reposted by Institute of Neurodegenerative Diseases
May #ImageOfTheMonth was from C.Mazocco & M.Darricau from @imn-bordeaux.bsky.social. Staining on spinal cord slices reveal TDP43 protein in the nucleus of neurons (Red). Motoneurons and synaptic terminations were stained targetting ChAT (Cyan).
June 5, 2025 at 8:44 AM
Reposted by Institute of Neurodegenerative Diseases
Our Paper, with Tom Polger @uofcincinnati.bsky.social & Jan Pieter Konsman @univbordeaux.bsky.social is part of the European Journal of neuroscience's Special issue 'The Relevance of a Philosophical Toolkit to Advance Neuroscience' @imn-bordeaux.bsky.social onlinelibrary.wiley.com/doi/toc/10.1...
The Relevance of a Philosophical Toolkit to Advance Neuroscience: European Journal of Neuroscience
Click on the title to browse this issue
onlinelibrary.wiley.com
May 25, 2025 at 9:00 PM