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IGFL

@igflyon.bsky.social

A strong focus on integrative, organism-level research at the interfaces of evolution, development & integrative physiology studied in lots of model systems
igfl.ens-lyon.fr

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IGFL

@igflyon.bsky.social

Excited to host Jean Livet (Institut de la Vision) at IGFL Lyon on June 30th! He’ll share how multicolor labeling and large-volume microscopy reveal the topography and topology of central sensory circuits. A must for connectomics fans! 🧠🔬✨

Flyer announcing a seminar by Jean Livet from the Institut de la Vision, hosted by Jonathan Enriquez at IGFL Lyon on June 30th, 2025. The talk is titled “Topography and topology in a central sensory neuronal projection.” The abstract explains that in the vertebrate brain, sensory pathways connect neuronal relays with high precision over long distances. To study these circuits, dense single-neuron tracing and large-volume microscopy are used. Jean Livet will discuss their efforts in connectomic mapping using multicolor labeling, focusing on an auditory relay to reveal its topographical and topological organization. The flyer also includes a short bio: Jean Livet completed his PhD on motor neuron development at IBDM Marseille, developed the Brainbow labeling method during his postdoc with Jeff W. Lichtman in the USA, and has led the “neurogenesis and circuit development” team at the Institut de la Vision since 2008.

June 23, 2025 at 1:38 PM

IGFL

@igflyon.bsky.social

🦋 Butterflies and beyond! Steven Van Belleghem is now at IGFL revealing how genomes evolve into pangenomes, shaping adaptation and gene regulation in butterflies and Daphnia. Don’t miss this dive into the mysteries of evolution! #EvolutionaryGenomics

Cartoon of Steven Van Belleghem riding a giant beetle over green islands, holding a camera and flying scientific papers. A hawk and butterfly accompany him, symbolizing his evolutionary genomics research on butterflies, Daphnia, and beetles.

June 2, 2025 at 9:15 AM

IGFL

@igflyon.bsky.social

🧬 From genomes to pangenomes to adaptation!
Join us June 2 at 11am in Salle des Thèses (IGFL) for Steven Van Belleghem’s talk on how structural genome variation and regulatory elements drive evolution—featuring butterflies, beetles, and Daphnia. 🦋🪲🦐

May 16, 2025 at 1:40 PM

IGFL

@igflyon.bsky.social

Live now at IGFL: Laure Bally-Cuif (Institut Pasteur) is sharing her fascinating work on the heterogeneity of adult neural stem cells. A deep dive into brain plasticity in action! #Neuroscience #IGFL #StemCells
@zenlabpasteur.bsky.social

May 5, 2025 at 9:10 AM

IGFL

@igflyon.bsky.social

🧠 Seminar alert! Laure Bally-Cuif (Pasteur Institute) will present:
"Individual cell heterogeneities and population dynamics for adult neural stem cell maintenance"
She will show how neural stem cell sub-populations sustain neurogenesis in zebrafish.
📅 05/05/25, 11am, Salle Condorcet ENS Lyon

April 25, 2025 at 12:17 PM

IGFL

@igflyon.bsky.social

Time to go mad! Thank you @zaycha.bsky.social for inviting @mads100tist.bsky.social for exciting science on somatosensory neuron diversity.

April 7, 2025 at 9:06 AM

IGFL

@igflyon.bsky.social

IGFL will be going mad next Monday, when we host @mads100tist.bsky.social, directly from Basel! We are looking forward to hearing an exciting talk!

April 1, 2025 at 9:51 PM

IGFL

@igflyon.bsky.social

Guest lecture today on Drosophila brain metabolism. Exciting results by Prof. Stefanie Schirmeier from TU Dresden.

March 17, 2025 at 10:10 AM

IGFL

@igflyon.bsky.social

Seminar alert! 🧠🔬 Prof. Stefanie Schirmeier (TU Dresden) presents "Metabolic flexibility of the Drosophila nervous system" on March 17th, 11 am at Salle Condorcet. Explore glial cells & adaptive metabolism! #Neuroscience #Metabolism

Title of the presentation
Metabolic flexibility of the Drosophila nervous system
Short abstract
Neuronal function consumes large amounts of energy. This energy needs to be provided in order to maintain homeostasis. To deal with this disproportionate demand, glial cells support neurons metabolically. Like their mammalian counterparts, Drosophila glial cells are very glycolytically active and provide lactate to the neurons under optimal conditions. Upon suboptimal conditions, several aspects of brain metabolism can be adapted. On the one hand, nutrient uptake into the nervous system is regulated to ensure nervous system function. On the other hand, glial cellular metabolism can adapt to changing conditions. E.g. when carbohydrate supply is not sufficient to meet the metabolic needs of the neurons, the glial cells switch to ß-oxidation of fatty acids and produce ketone bodies as an alternate fuel that they supply to neurons. It turns out that glial metabolism can be adapted to different conditions, like starvation or cold exposure, in different ways to ensure neuronal function.
Short CV
Stefanie Schirmeier graduated from the University of Bayreuth (Germany) and joined Dominique Ferrandon’s team at the University of Strasbourg (France), where she studied host-pathogen interactions using Drosophila melanogaster as a model. She contributed to a genome-wide genetic screen and discovered the compensatory proliferation of intestinal stem cells in response to gut infection, as well as identifying a bacterial virulence factor required to counteract the cellular immune response.
She then moved to the University of Münster (Germany) for a postdoctoral position, joining Christian Klämbt’s team and later establishing her own research group there. Stefanie focused on investigating the physiology and metabolism of glial cells and uncovered their role in neuronal nutritional support via the astrocyte-neuron lactate shuttle.
Since 2021, Stefanie has been a professor at Dresden Technic…

March 13, 2025 at 2:58 PM

IGFL

@igflyon.bsky.social

🌱 New findings on kelp zygotes! Bénédicte Charrier’s team shows how alginate forms a corset, shaping early cell fate.

🔬 Read the Scientific Reports paper: www.nature.com/articles/s41...

🖼️ Kelp zygote: alginate corset (green), nucleus (blue), chloroplasts (red). Length: 30 µm.

January 10, 2025 at 5:51 PM

IGFL

@igflyon.bsky.social

Congratulations @francoisleulier.bsky.social, recipient of the Jaffé Prize - Fondation de l'Institut de France. This award honors work or experiences aimed at advancing progress and the well-being of humanity.

November 26, 2024 at 3:12 PM

IGFL

@igflyon.bsky.social

Poste d'IE à pourvoir dans l'équipe "Physiologie intégrative des interactions hôte/microbes". Les candidatures sont à déposer exclusivement sur le portail emploi du CNRS.