Intermittent Fasting
@ifdiet.bsky.social
Steve Mount on intermittent fasting, metabolic health, aging and longevity, with a focus on the science.
Intermittent fasting is sustainable; I've been at it for over 20 years.
Intermittent fasting is sustainable; I've been at it for over 20 years.
I agree. It would greatly simplify planning meetings with remote participation.
But there still has to be agreement on standard times.
Are the 9-to-5ers going to be 16:00-24:00 or 17:00-1:00? Would people ever use UTC for things like store hours?
It reminds me of conversion to metric.
But there still has to be agreement on standard times.
Are the 9-to-5ers going to be 16:00-24:00 or 17:00-1:00? Would people ever use UTC for things like store hours?
It reminds me of conversion to metric.
December 15, 2024 at 4:47 PM
I agree. It would greatly simplify planning meetings with remote participation.
But there still has to be agreement on standard times.
Are the 9-to-5ers going to be 16:00-24:00 or 17:00-1:00? Would people ever use UTC for things like store hours?
It reminds me of conversion to metric.
But there still has to be agreement on standard times.
Are the 9-to-5ers going to be 16:00-24:00 or 17:00-1:00? Would people ever use UTC for things like store hours?
It reminds me of conversion to metric.
Reposted by Intermittent Fasting
And now this. My father had polio when he was a child in the 1930s. He thankfully survived. Many did not. This is, well, evil. Let's not mince words. www.nytimes.com/2024/12/13/h...
Kennedy’s Lawyer Has Asked the F.D.A. to Revoke Approval of the Polio Vaccine
Aaron Siri, who specializes in vaccine lawsuits, has been at Robert F. Kennedy Jr.’s side reviewing candidates for top jobs at the Department of Health and Human Services.
www.nytimes.com
December 13, 2024 at 11:49 AM
And now this. My father had polio when he was a child in the 1930s. He thankfully survived. Many did not. This is, well, evil. Let's not mince words. www.nytimes.com/2024/12/13/h...
Reposted by Intermittent Fasting
The WaPo article is largely based on Oh et al. in Nature.
pubmed.ncbi.nlm.nih.gov/38057571/
"Accelerated heart aging ... 250% increased heart failure risk and accelerated brain and vascular aging predict Alzheimer's disease (AD) progression independently from and as strongly as plasma pTau-181."
pubmed.ncbi.nlm.nih.gov/38057571/
"Accelerated heart aging ... 250% increased heart failure risk and accelerated brain and vascular aging predict Alzheimer's disease (AD) progression independently from and as strongly as plasma pTau-181."
Organ aging signatures in the plasma proteome track health and disease - PubMed
Animal studies show aging varies between individuals as well as between organs within an individual<sup>1-4</sup>, but whether this is true in humans and its effect on age-related diseases is unknown....
pubmed.ncbi.nlm.nih.gov
November 28, 2024 at 3:05 PM
The WaPo article is largely based on Oh et al. in Nature.
pubmed.ncbi.nlm.nih.gov/38057571/
"Accelerated heart aging ... 250% increased heart failure risk and accelerated brain and vascular aging predict Alzheimer's disease (AD) progression independently from and as strongly as plasma pTau-181."
pubmed.ncbi.nlm.nih.gov/38057571/
"Accelerated heart aging ... 250% increased heart failure risk and accelerated brain and vascular aging predict Alzheimer's disease (AD) progression independently from and as strongly as plasma pTau-181."
You want to look at the original article in Nature.
pubmed.ncbi.nlm.nih.gov/38057571/
They did use machine learning models. "nearly 20% of the population show strongly accelerated age in one organ and 1.7% are multi-organ agers. Accelerated organ aging confers 20-50% higher mortality risk."
pubmed.ncbi.nlm.nih.gov/38057571/
They did use machine learning models. "nearly 20% of the population show strongly accelerated age in one organ and 1.7% are multi-organ agers. Accelerated organ aging confers 20-50% higher mortality risk."
Organ aging signatures in the plasma proteome track health and disease - PubMed
Animal studies show aging varies between individuals as well as between organs within an individual<sup>1-4</sup>, but whether this is true in humans and its effect on age-related diseases is unknown....
pubmed.ncbi.nlm.nih.gov
November 28, 2024 at 2:59 PM
You want to look at the original article in Nature.
pubmed.ncbi.nlm.nih.gov/38057571/
They did use machine learning models. "nearly 20% of the population show strongly accelerated age in one organ and 1.7% are multi-organ agers. Accelerated organ aging confers 20-50% higher mortality risk."
pubmed.ncbi.nlm.nih.gov/38057571/
They did use machine learning models. "nearly 20% of the population show strongly accelerated age in one organ and 1.7% are multi-organ agers. Accelerated organ aging confers 20-50% higher mortality risk."
The life span extension of mutations in insulin pathway genes in C. elegans was an important component of my thinking when I started intermittent fasting. It still is.
November 23, 2024 at 11:55 PM
The life span extension of mutations in insulin pathway genes in C. elegans was an important component of my thinking when I started intermittent fasting. It still is.