Iannetti Lab
iannettilab.bsky.social
Iannetti Lab
@iannettilab.bsky.social
Neuroscience Laboratory led by Giandomenico Iannetti based at the Italian Institute of Technology and University College London | @iitalk.bsky.social, @ucl.ac.uk
8/ So we demonstrate that #surprise interferes with ongoing cortical functions across different #brain systems - i.e., not only at the level of the motor output but already at the sensory input - and thereby influences global brain dynamics.
October 21, 2025 at 8:50 AM
7/ We observed that the amplitude of somatosensory responses did change as a function of the Vertex Potential phase! Thus, a large VP may reflect the rapid alternation of periods of depressed and enhanced cortical excitability, as it occurs during #sleep slow waves.
October 21, 2025 at 8:50 AM
8/ This framework unites decades of fragmented data — from monkey neurophysiology to human EEG — into a single, testable theory. Just as hippocampal place cells map the world for navigation, peripersonal neurons map value around the body — for action.
June 4, 2025 at 9:51 AM
7/ These ANNs also naturally separate into sub-networks specialised for avoidance and interception, mirroring the modularity of both the macaque brain and the egocentric value map that we proposed.
June 4, 2025 at 9:51 AM
6/ Remarkably, these action value fields naturally assemble into an *egocentric map*: a modular, composable predictive model of the world around the body, which allows rapid adaptation to novel situations by recombining existing knowledge.
June 4, 2025 at 9:51 AM
5/ To test this, we used #ReinforcementLearning and computational modelling. We trained agents to interact with the world — and their networks spontaneously developed body-part-centered fields, not because of spatial proximity, but *because of value*.
June 4, 2025 at 9:51 AM
4/ Our key insight was that peripersonal responses might not simply reflect stimulus configuration, but *action values* — the expected rewards or punishments from contacting objects.
June 4, 2025 at 9:51 AM
3/ For decades we've known of neurons responsive to objects near the body—aka peripersonal neurons—initially viewed as proximity detectors.

However, these neurons also respond to stimulus value, speed, and motor repertoire.

Why are these neurons so flexible? What are they for?
June 4, 2025 at 9:51 AM
2/ We show that #peripersonal neurons aren’t just proximity detectors — they encode the value of interacting with objects.

Together, they form egocentric value maps: short-term predictive models of the near-body space, akin to hippocampal maps of far space.

Short story below!
June 4, 2025 at 9:51 AM