Holly Beale
@hollybeale.bsky.social
Staff scientist at🌲UCSC, passionate about pediatric cancer transcriptomics, social justice, and 🐕 genomics. She/her/hers.
https://orcid.org/0000-0003-4091-538X
https://orcid.org/0000-0003-4091-538X
Some dog genetic signals are easily detectable by assigning individual dogs the phenotype from its breed, but the approach has many confounders. www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
November 30, 2025 at 9:12 PM
Some dog genetic signals are easily detectable by assigning individual dogs the phenotype from its breed, but the approach has many confounders. www.pnas.org/doi/10.1073/...
I was lucky enough to see her in 2019. It's not only her scientific insights that were so impressive; it's the way she kept broadening her perspective over the course of her life.
JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
Jane Goodall, legendary primatologist, has died at age 91
Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
n.pr
October 1, 2025 at 7:45 PM
I was lucky enough to see her in 2019. It's not only her scientific insights that were so impressive; it's the way she kept broadening her perspective over the course of her life.
Reposted by Holly Beale
JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
Jane Goodall, legendary primatologist, has died at age 91
Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
n.pr
October 1, 2025 at 6:34 PM
JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.
Reposted by Holly Beale
This baby flamingo is so adorable… 🥰
🦩
🦩
July 31, 2025 at 10:42 PM
This baby flamingo is so adorable… 🥰
🦩
🦩
Blood, sweat and (happy) tears: we've published about our freely available collections of more than 16k consistently processed, QC'd bulk RNA-Seq datasets (with a focus on pediatric cancer). rdcu.be/euuSd
Consistently processed RNA sequencing data from 50 sources enriched for pediatric data
Scientific Data - Consistently processed RNA sequencing data from 50 sources enriched for pediatric data
rdcu.be
July 2, 2025 at 9:40 PM
Blood, sweat and (happy) tears: we've published about our freely available collections of more than 16k consistently processed, QC'd bulk RNA-Seq datasets (with a focus on pediatric cancer). rdcu.be/euuSd
It’s incredible that this decision is presented as strategic misdirection rather than impulsivity. This should be in the opinion section. www.nytimes.com/2025/06/22/u...
Shifting Views and Misdirection: How Trump Decided to Strike Iran
www.nytimes.com
June 23, 2025 at 4:07 PM
It’s incredible that this decision is presented as strategic misdirection rather than impulsivity. This should be in the opinion section. www.nytimes.com/2025/06/22/u...
Reposted by Holly Beale
This is an amazing learning project :). Also, I agree that if you're looking for a super fast and fun (and safe) language to learn, Rust has you covered! BFX is leading, I think, in Rust adoption in science; let's keep it that way!
I started tgv to learn Rust and building it has been unbelievably fun! If you wanna pick up a super fast and fun programming language, tgv is open for contribution! There aren't many bioinformatics tools built entirely by the community. If tgv can become one, I'll be so psyched
Terminal Genome Viewer (tgv), written in Rust github.com/zeqianli/tgv
May 28, 2025 at 12:38 PM
This is an amazing learning project :). Also, I agree that if you're looking for a super fast and fun (and safe) language to learn, Rust has you covered! BFX is leading, I think, in Rust adoption in science; let's keep it that way!
Reposted by Holly Beale
what booker is doing right now is an example of what i mean when i say things like “we need more ambition right now.” there is room in american politics right now for people with ambition to take big stands and reap the rewards. he’s doing it!
April 1, 2025 at 8:24 PM
what booker is doing right now is an example of what i mean when i say things like “we need more ambition right now.” there is room in american politics right now for people with ambition to take big stands and reap the rewards. he’s doing it!
Reposted by Holly Beale
They killed LIHEAP, which helps poor people not freeze to death in the winter because of unpaid heating bills.
April 1, 2025 at 8:12 PM
They killed LIHEAP, which helps poor people not freeze to death in the winter because of unpaid heating bills.
Reposted by Holly Beale
She died in binary. That’s dedication. RIP.
Bletchley Park code breaker Betty Webb dies aged 101
Bletchley Park code breaker Betty Webb dies aged 101
Betty Webb MBE worked at Bletchley Park during World War Two intercepting enemy messages.
www.bbc.com
April 1, 2025 at 12:05 PM
She died in binary. That’s dedication. RIP.
Reposted by Holly Beale
Also the importance of showing the data to your organism
March 17, 2025 at 4:51 PM
Also the importance of showing the data to your organism
Reposted by Holly Beale
Went to check out this article in Oxford #Bioinformatics, and dude ... I was not prepared for this font!
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
March 4, 2025 at 3:13 PM
Went to check out this article in Oxford #Bioinformatics, and dude ... I was not prepared for this font!
academic.oup.com/bioinformati...
academic.oup.com/bioinformati...
Reposted by Holly Beale
"We will not retract published articles on request by an author on the basis that they contain so-called banned words"
@bmj.com takes a stand: "Medical journal editors must resist CDC order and anti-gender ideology"
www.bmj.com/content/388/...
@bmj.com takes a stand: "Medical journal editors must resist CDC order and anti-gender ideology"
www.bmj.com/content/388/...
Medical journal editors must resist CDC order and anti-gender ideology
The news that on 31 January 2025 the Trump administration instructed scientists employed by the US Centers for Disease Control and Prevention (CDC) to withdraw or retract articles from medical and sci...
www.bmj.com
February 4, 2025 at 7:08 PM
"We will not retract published articles on request by an author on the basis that they contain so-called banned words"
@bmj.com takes a stand: "Medical journal editors must resist CDC order and anti-gender ideology"
www.bmj.com/content/388/...
@bmj.com takes a stand: "Medical journal editors must resist CDC order and anti-gender ideology"
www.bmj.com/content/388/...
Reposted by Holly Beale
"We have to allow this [org/shelter/hospital/school] to erase the trans community and comply to save everyone else"
Absolutely not.
I will not allow my community to be jettisoned to save yourself. Yes, if you don't, other groups may suffer, and you might too.
But we are all in this together.
Absolutely not.
I will not allow my community to be jettisoned to save yourself. Yes, if you don't, other groups may suffer, and you might too.
But we are all in this together.
January 31, 2025 at 6:24 PM
"We have to allow this [org/shelter/hospital/school] to erase the trans community and comply to save everyone else"
Absolutely not.
I will not allow my community to be jettisoned to save yourself. Yes, if you don't, other groups may suffer, and you might too.
But we are all in this together.
Absolutely not.
I will not allow my community to be jettisoned to save yourself. Yes, if you don't, other groups may suffer, and you might too.
But we are all in this together.
Reposted by Holly Beale
Okay, I cannot recommend 5calls.org enough. Enter your address and it will find all your reps (federal and state). AND give you a list of issues to call about AND which reps to call about each of them AND a little script for each, in case it's helpful. They have an app, too.
5 Calls
Spend 5 minutes. Make 5 calls. Make your voice heard.
5calls.org
January 30, 2025 at 5:08 PM
Okay, I cannot recommend 5calls.org enough. Enter your address and it will find all your reps (federal and state). AND give you a list of issues to call about AND which reps to call about each of them AND a little script for each, in case it's helpful. They have an app, too.
Reposted by Holly Beale
There is no LGB without the TQIA+
We stand together or we fall together.
🏳️🌈 🏳️⚧️
We stand together or we fall together.
🏳️🌈 🏳️⚧️
February 1, 2025 at 12:50 AM
There is no LGB without the TQIA+
We stand together or we fall together.
🏳️🌈 🏳️⚧️
We stand together or we fall together.
🏳️🌈 🏳️⚧️
Reposted by Holly Beale
The next four years feel like a technical challenge where the only instructions Paul Hollywood gave us were “survive” and the ingredients are Chuck Schumer.
January 31, 2025 at 4:12 PM
The next four years feel like a technical challenge where the only instructions Paul Hollywood gave us were “survive” and the ingredients are Chuck Schumer.
Reposted by Holly Beale
If you are in danger unless you comply with a regime, you are in danger whether you comply or not
January 31, 2025 at 9:16 PM
If you are in danger unless you comply with a regime, you are in danger whether you comply or not
Reposted by Holly Beale
Everyone who makes a decision about what actions to take on campus right now is personally responsible for not complying in advance and we need to all remember that.
Most of these orders are illegal, unethical, and unconstitutional. Our democracy only works if we don't follow orders like that.
Most of these orders are illegal, unethical, and unconstitutional. Our democracy only works if we don't follow orders like that.
January 31, 2025 at 5:48 PM
Everyone who makes a decision about what actions to take on campus right now is personally responsible for not complying in advance and we need to all remember that.
Most of these orders are illegal, unethical, and unconstitutional. Our democracy only works if we don't follow orders like that.
Most of these orders are illegal, unethical, and unconstitutional. Our democracy only works if we don't follow orders like that.
Reposted by Holly Beale
This is all good analysis.
Side note: This whole event is really highlighting to me the surprisingly large power of individual choices amongst this chaos. This wasn't a top down decision, this was a few people acting on limited information. But at first glance it has the effect of (1/n)
Side note: This whole event is really highlighting to me the surprisingly large power of individual choices amongst this chaos. This wasn't a top down decision, this was a few people acting on limited information. But at first glance it has the effect of (1/n)
Brief analysis of what we're seeing right now in U.S. higher ed with those rushing to over-comply with Trump's anti-DEI executive order, like MSU --
Short 🧵
Short 🧵
January 31, 2025 at 5:48 PM
This is all good analysis.
Side note: This whole event is really highlighting to me the surprisingly large power of individual choices amongst this chaos. This wasn't a top down decision, this was a few people acting on limited information. But at first glance it has the effect of (1/n)
Side note: This whole event is really highlighting to me the surprisingly large power of individual choices amongst this chaos. This wasn't a top down decision, this was a few people acting on limited information. But at first glance it has the effect of (1/n)
Reposted by Holly Beale
tomorrow's phone calls: the Democrats need to have a plan. For better or worse, they are now an opposition party.
It is clear the Trump is not governing in good faith and they need to throw sand in the gears of any future legislation/nominations/executive orders to limit, if not prevent, harm.
It is clear the Trump is not governing in good faith and they need to throw sand in the gears of any future legislation/nominations/executive orders to limit, if not prevent, harm.
I just contacted my representatives about the nomination of RFK, Jr and the recent executive orders. Here is what I wrote in my email or said to the staffer on the phone:
Hello-
I am writing/calling on several topics:
Hello-
I am writing/calling on several topics:
January 29, 2025 at 1:27 AM
tomorrow's phone calls: the Democrats need to have a plan. For better or worse, they are now an opposition party.
It is clear the Trump is not governing in good faith and they need to throw sand in the gears of any future legislation/nominations/executive orders to limit, if not prevent, harm.
It is clear the Trump is not governing in good faith and they need to throw sand in the gears of any future legislation/nominations/executive orders to limit, if not prevent, harm.
Reposted by Holly Beale
I just contacted my representatives about the nomination of RFK, Jr and the recent executive orders. Here is what I wrote in my email or said to the staffer on the phone:
Hello-
I am writing/calling on several topics:
Hello-
I am writing/calling on several topics:
January 28, 2025 at 6:50 PM
I just contacted my representatives about the nomination of RFK, Jr and the recent executive orders. Here is what I wrote in my email or said to the staffer on the phone:
Hello-
I am writing/calling on several topics:
Hello-
I am writing/calling on several topics:
No federal disbursements? Then we stop paying federal taxes. We need a mass movement to hamstring this administration. wapo.st/40M97df
Trump order targets transgender troops and ‘radical gender ideology’
The president’s executive order took aim at transgender individuals in personal terms, noting that physical and mental health conditions make them “incompatible” with military service.
wapo.st
January 28, 2025 at 2:30 PM
No federal disbursements? Then we stop paying federal taxes. We need a mass movement to hamstring this administration. wapo.st/40M97df
Reposted by Holly Beale
Omg the sheriff’s office posted an update and she’s doing so good 😭😭😭
January 28, 2025 at 2:54 AM
Omg the sheriff’s office posted an update and she’s doing so good 😭😭😭
Great terminal basics program:
sandbox.bio/tutorials/te...
sandbox.bio/tutorials/te...
sandbox.bio
January 27, 2025 at 4:59 PM
Great terminal basics program:
sandbox.bio/tutorials/te...
sandbox.bio/tutorials/te...