doi.org/10.1016/j.kint.2025.09.026
#NephSky #MedSky #lupus #nupusnephritis #kidneydisease
@vhir.bsky.social @lmumuenchen.bsky.social @hjanders.bsky.social @pepasolerr.bsky.social
doi.org/10.1016/j.kint.2025.09.026
#NephSky #MedSky #lupus #nupusnephritis #kidneydisease
@vhir.bsky.social @lmumuenchen.bsky.social @hjanders.bsky.social @pepasolerr.bsky.social
Rationale, Design, and Baseline Characteristics of the TRANSCEND-CKD trial of Retatrutide in pts with CKD
🧐Retatrutide is a novel triple incretin agonist targeting GIP, GLP-1, and glucagon receptors
▶️ academic.oup.com/ndt/article/...
Rationale, Design, and Baseline Characteristics of the TRANSCEND-CKD trial of Retatrutide in pts with CKD
🧐Retatrutide is a novel triple incretin agonist targeting GIP, GLP-1, and glucagon receptors
▶️ academic.oup.com/ndt/article/...
Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) in Chinese Pts
🧐This Chinese ADTKD cohort reveals a high prevalence of UMOD and HNF1B variants
▶️ academic.oup.com/ndt/article-...
Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) in Chinese Pts
🧐This Chinese ADTKD cohort reveals a high prevalence of UMOD and HNF1B variants
▶️ academic.oup.com/ndt/article-...
Neutrophil infiltration of kidney grafts: incidence, associated factors and graft survival
🧐NTI should prompt the search for urinary tract infection and rejection
▶️ academic.oup.com/ndt/article-...
Neutrophil infiltration of kidney grafts: incidence, associated factors and graft survival
🧐NTI should prompt the search for urinary tract infection and rejection
▶️ academic.oup.com/ndt/article-...
Recombinant alpha-1 microglobulin to improve outcomes in survivors of AKI
🧐RMC-035 may improve kidney outcomes in settings characterized by oxidative and ischemia-reperfusion injury.
▶️ academic.oup.com/ndt/article-...
Recombinant alpha-1 microglobulin to improve outcomes in survivors of AKI
🧐RMC-035 may improve kidney outcomes in settings characterized by oxidative and ischemia-reperfusion injury.
▶️ academic.oup.com/ndt/article-...
How can we target the production of pathogenic IgA in IgAN?
🧐Drugs directed at mucosal B cells, inhibitors of APRIL and BAFF, and drugs that target IgA-producing plasma cells
▶️https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf185/8262262
How can we target the production of pathogenic IgA in IgAN?
🧐Drugs directed at mucosal B cells, inhibitors of APRIL and BAFF, and drugs that target IgA-producing plasma cells
▶️https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf185/8262262
Recombinant alpha-1 microglobulin to improve outcomes in survivors of AKI
🧐RMC-035 may improve kidney outcomes in settings characterized by oxidative and ischemia-reperfusion injury.
▶️ academic.oup.com/ndt/article-...
Recombinant alpha-1 microglobulin to improve outcomes in survivors of AKI
🧐RMC-035 may improve kidney outcomes in settings characterized by oxidative and ischemia-reperfusion injury.
▶️ academic.oup.com/ndt/article-...
Prevalence of Strongyloides stercoralis in HD pts in Vienna
🧐Implementation of targeted screening for S. stercoralis should be considered in pre-KTX protocols in Europe.
▶️ academic.oup.com/ndt/article/...
Prevalence of Strongyloides stercoralis in HD pts in Vienna
🧐Implementation of targeted screening for S. stercoralis should be considered in pre-KTX protocols in Europe.
▶️ academic.oup.com/ndt/article/...
QT-Prolonging Medications: Prevalence of Use and Associated Risks in CKD
🧐The pathophysiological relevance, prevalence, and CV consequences of QT-prolonging drug use in the CKD setting
▶️https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf196/8263915
QT-Prolonging Medications: Prevalence of Use and Associated Risks in CKD
🧐The pathophysiological relevance, prevalence, and CV consequences of QT-prolonging drug use in the CKD setting
▶️https://academic.oup.com/ndt/article/doi/10.1093/ndt/gfaf196/8263915
Anti-GBM disease - Treatment Standard
🧐 Anti-GBM and ANCA positive pts have a higher relapse risk and require maintenance immunosuppressive treatment
▶️ academic.oup.com/ndt/article/...
Anti-GBM disease - Treatment Standard
🧐 Anti-GBM and ANCA positive pts have a higher relapse risk and require maintenance immunosuppressive treatment
▶️ academic.oup.com/ndt/article/...
Comparing CKD populations with T1D and T2D based on FINE-ONE and FIDELITY populations
🧐Similarities between populations may inform the translation of clinical evidence on finerenone from CKD and T2D to CKD and T1D.
▶️ academic.oup.com/ndt/article/...
Comparing CKD populations with T1D and T2D based on FINE-ONE and FIDELITY populations
🧐Similarities between populations may inform the translation of clinical evidence on finerenone from CKD and T2D to CKD and T1D.
▶️ academic.oup.com/ndt/article/...
CKD of unexplained cause (CKDx): A consensus statement by the Genes &Kidney Working Group of the ERA
🧐Check also our 2 open access editorials on this innovative concept.
▶️ academic.oup.com/ndt/article/...
CKD of unexplained cause (CKDx): A consensus statement by the Genes &Kidney Working Group of the ERA
🧐Check also our 2 open access editorials on this innovative concept.
▶️ academic.oup.com/ndt/article/...
Transition of pts with hereditary nephropathies from pediatric to adult care
from WG Genes&Kidney of ERA and ESPN
🧐To improve health outcomes, pt empowerment, and engagement for young people with CKD.
▶️ academic.oup.com/ndt/article-...
Transition of pts with hereditary nephropathies from pediatric to adult care
from WG Genes&Kidney of ERA and ESPN
🧐To improve health outcomes, pt empowerment, and engagement for young people with CKD.
▶️ academic.oup.com/ndt/article-...
Additive Effects of Oral Calcitriol on pts with IgAN receiving RAS Blockade
🧐The addition of 0.25 μg/d calcitriol to RASi safely lowered residual proteinuria and slowed eGFR decline in pts with IgAN
▶️ academic.oup.com/ndt/article-...
Additive Effects of Oral Calcitriol on pts with IgAN receiving RAS Blockade
🧐The addition of 0.25 μg/d calcitriol to RASi safely lowered residual proteinuria and slowed eGFR decline in pts with IgAN
▶️ academic.oup.com/ndt/article-...
Protein profiles and associated biological pathways among different etiologies of CKD: new insights from DAPA-CKD
🧐Distinct proteomic differences unravel the heterogeneous pathophysiology of human CKD.
▶️ academic.oup.com/ndt/article/...
Protein profiles and associated biological pathways among different etiologies of CKD: new insights from DAPA-CKD
🧐Distinct proteomic differences unravel the heterogeneous pathophysiology of human CKD.
▶️ academic.oup.com/ndt/article/...
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@ndt-era.bsky.social, @hjanders.bsky.social
More info: academic.oup.com/ndt/article/...
@ndt-era.bsky.social, @hjanders.bsky.social
More info: academic.oup.com/ndt/article/...
@ndt-era.bsky.social, @hjanders.bsky.social
More info: academic.oup.com/ndt/article/...
@ndt-era.bsky.social, @hjanders.bsky.social
More info: academic.oup.com/ndt/article/...
@ndt-era.bsky.social, @hjanders.bsky.social, @Richard Glassock, @Andrew Rule, @Aleksandar Denic, @delanaye.bsky.social
More info: academic.oup.com/ndt/article/...
@ndt-era.bsky.social, @hjanders.bsky.social, @Richard Glassock, @Andrew Rule, @Aleksandar Denic, @delanaye.bsky.social
Cost-effectiveness of protein restricted diets in advanced CKD
🧐In pts adherent to diet prescription, low-protein diets delay the start of dialysis, improve survival, and save money
▶️ academic.oup.com/ndt/article-...
Cost-effectiveness of protein restricted diets in advanced CKD
🧐In pts adherent to diet prescription, low-protein diets delay the start of dialysis, improve survival, and save money
▶️ academic.oup.com/ndt/article-...
Anti-nephrin, anti-podocin and anti-Kirrel1 antibodies: Biological challenges and clinical implications
🧐 Clinical implementation of anti-slit diaphragm antibody testing = precision dx and tx in podocytopathies
▶️ academic.oup.com/ndt/article/...
Anti-nephrin, anti-podocin and anti-Kirrel1 antibodies: Biological challenges and clinical implications
🧐 Clinical implementation of anti-slit diaphragm antibody testing = precision dx and tx in podocytopathies
▶️ academic.oup.com/ndt/article/...
What do RCTs teach us about the pathophysiology of human IgAN?
🧐B cells/PC produce the IgAN antigen GdIgA1 as well as the respective autoantibodies, hence targeting B cells/PC will be most clever.
▶️ academic.oup.com/ndt/article/...
What do RCTs teach us about the pathophysiology of human IgAN?
🧐B cells/PC produce the IgAN antigen GdIgA1 as well as the respective autoantibodies, hence targeting B cells/PC will be most clever.
▶️ academic.oup.com/ndt/article/...
Perlecan is a novel target of autoantibodies in anti-glomerular basement membrane disease
🧐Triple-positive pts (anti-type IV collagen, -laminin 521, and -perlecan) = highest prevalence of lung hemorrhage and ESKD
▶️ academic.oup.com/ndt/article-...
Perlecan is a novel target of autoantibodies in anti-glomerular basement membrane disease
🧐Triple-positive pts (anti-type IV collagen, -laminin 521, and -perlecan) = highest prevalence of lung hemorrhage and ESKD
▶️ academic.oup.com/ndt/article-...
Evolving strategies for early diagnosis, proactive prevention and treatment of CKD
🧐"Inferior doctors provide KRT
Mediocre doctors treat CKD
Superior doctors prevent kidney disease"
▶️
academic.oup.com/ndt/article/...
Evolving strategies for early diagnosis, proactive prevention and treatment of CKD
🧐"Inferior doctors provide KRT
Mediocre doctors treat CKD
Superior doctors prevent kidney disease"
▶️
academic.oup.com/ndt/article/...
academic.oup.com/ndt/article/...
academic.oup.com/ndt/article/...