Michael Hiller
@hillermich.bsky.social
Prof. of Comparative Genomics @ Senckenberg Frankfurt; Genomics, Evolution, Comp Bio & the Phenotype-Genotype Question
Reposted by Michael Hiller
🚀🧬🔥 Hot off the press — 2025!
Don’t miss this must-read publication: bit.ly/4mJwFb7
This groundbreaking paper sets the stage for Earth BioGenome Project Phase II — where EBP is gearing up to scale genome sequencing 10× faster than ever before! 🌍✨
Don’t miss this must-read publication: bit.ly/4mJwFb7
This groundbreaking paper sets the stage for Earth BioGenome Project Phase II — where EBP is gearing up to scale genome sequencing 10× faster than ever before! 🌍✨
September 4, 2025 at 2:40 PM
🚀🧬🔥 Hot off the press — 2025!
Don’t miss this must-read publication: bit.ly/4mJwFb7
This groundbreaking paper sets the stage for Earth BioGenome Project Phase II — where EBP is gearing up to scale genome sequencing 10× faster than ever before! 🌍✨
Don’t miss this must-read publication: bit.ly/4mJwFb7
This groundbreaking paper sets the stage for Earth BioGenome Project Phase II — where EBP is gearing up to scale genome sequencing 10× faster than ever before! 🌍✨
phenomenal work from Terry's lab !! And unbelievable that funding for such exciting work is cut.
1) I am delighted to present this terrific tour de force research conducted by my post-doc Dr. Gayani Senevirathne @gayani.bsky.social and published today in Nature -
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The evolution of hominin bipedalism in two steps - Nature
The human pelvis exhibits distinct spatiotemporal ossification patterns and an ilium cartilage growth plate that is shifted perpendicularly compared with those of other mammals and non-human primates—...
www.nature.com
September 3, 2025 at 6:54 AM
phenomenal work from Terry's lab !! And unbelievable that funding for such exciting work is cut.
Back from the Biology of Aging Gordon Research Conference. Fantastic meeting. Great to meet old friends and making new ones.
August 9, 2025 at 7:32 AM
Back from the Biology of Aging Gordon Research Conference. Fantastic meeting. Great to meet old friends and making new ones.
Happy to share our review on "Linking phenotype to genotype using comprehensive genomic comparisons" in Current Op with @leonhilgers.bsky.social. Summary of recent work and a discussion of the challenges ahead. www.sciencedirect.com/science/arti...
August 1, 2025 at 4:13 PM
Happy to share our review on "Linking phenotype to genotype using comprehensive genomic comparisons" in Current Op with @leonhilgers.bsky.social. Summary of recent work and a discussion of the challenges ahead. www.sciencedirect.com/science/arti...
Reposted by Michael Hiller
You link #phenotype 🦜 to #genotype 🧬 with #comparative #genomics 💻?
This #review is for you 📜: authors.elsevier.com/sd/article/S...
We review new #methods, remaining #challenges and #future directions and highlight recent key studies.
Thanks @hillermich.bsky.social!
Please share! 🙂
This #review is for you 📜: authors.elsevier.com/sd/article/S...
We review new #methods, remaining #challenges and #future directions and highlight recent key studies.
Thanks @hillermich.bsky.social!
Please share! 🙂
July 24, 2025 at 8:00 AM
You link #phenotype 🦜 to #genotype 🧬 with #comparative #genomics 💻?
This #review is for you 📜: authors.elsevier.com/sd/article/S...
We review new #methods, remaining #challenges and #future directions and highlight recent key studies.
Thanks @hillermich.bsky.social!
Please share! 🙂
This #review is for you 📜: authors.elsevier.com/sd/article/S...
We review new #methods, remaining #challenges and #future directions and highlight recent key studies.
Thanks @hillermich.bsky.social!
Please share! 🙂
And @pacbio.bsky.social updated the ultralow protocol based on our results. Checkout www.pacb.com/blog/new-amp...
New Ampli-Fi ultra-low-input protocol will support HiFi sequencing from as little as 1 ng of DNA - PacBio
The Ampli-Fi protocol is a new workflow that will enable HiFi sequencing from as little as 1 ng of genomic DNA.
www.pacb.com
February 11, 2025 at 9:03 AM
And @pacbio.bsky.social updated the ultralow protocol based on our results. Checkout www.pacb.com/blog/new-amp...
Our work on long read sequencing of ethanol or difficult-to-sequence samples is out genomebiology.biomedcentral.com/articles/10..... Will help to sequence Earth's biodiversity @ebpgenome.bsky.social. w @bernhardbein.bsky.social & many great colleagues.
February 11, 2025 at 9:01 AM
Our work on long read sequencing of ethanol or difficult-to-sequence samples is out genomebiology.biomedcentral.com/articles/10..... Will help to sequence Earth's biodiversity @ebpgenome.bsky.social. w @bernhardbein.bsky.social & many great colleagues.
Checkout @xuelingyi.bsky.social manuscript on diet evolution in bats, with a focus on the super diverse Phyllostomid bat family. www.biorxiv.org/content/10.1...
February 9, 2025 at 8:24 AM
Checkout @xuelingyi.bsky.social manuscript on diet evolution in bats, with a focus on the super diverse Phyllostomid bat family. www.biorxiv.org/content/10.1...
To all #PSMC users. A prominent PSMC peak followed by a collapse is typically an artifact. @leonhilgers.bsky.social publiation in @currentbiology.bsky.social shows how to avoid this with simple parameter adjustments. www.cell.com/current-biol...
February 7, 2025 at 6:48 AM
To all #PSMC users. A prominent PSMC peak followed by a collapse is typically an artifact. @leonhilgers.bsky.social publiation in @currentbiology.bsky.social shows how to avoid this with simple parameter adjustments. www.cell.com/current-biol...
Reposted by Michael Hiller
I am writing a short #review about linking #phenotype to #genotype 🧬using #comparative #genomics. There is a lot of amazing work and I would love to hear about your favorite studies 🥇 from the last 2-3 years! ✉️
Pls also send your own work here (or DM)🙂!!
Please #repost!!! 🔁
(just joined bsky)
Pls also send your own work here (or DM)🙂!!
Please #repost!!! 🔁
(just joined bsky)
an owl holding an envelope with a label that says ' envelope ' on it
ALT: an owl holding an envelope with a label that says ' envelope ' on it
media.tenor.com
February 6, 2025 at 11:40 AM
I am writing a short #review about linking #phenotype to #genotype 🧬using #comparative #genomics. There is a lot of amazing work and I would love to hear about your favorite studies 🥇 from the last 2-3 years! ✉️
Pls also send your own work here (or DM)🙂!!
Please #repost!!! 🔁
(just joined bsky)
Pls also send your own work here (or DM)🙂!!
Please #repost!!! 🔁
(just joined bsky)
Reposted by Michael Hiller
A news article for a lay summary also: www.nature.com/articles/d41...
How flight helped bats become invincible to viruses
The mammals carry immune adaptations that emerged when their ancestors took to the skies.
www.nature.com
January 30, 2025 at 2:34 AM
A news article for a lay summary also: www.nature.com/articles/d41...
Reposted by Michael Hiller
Finally online - Bat genomes illuminate adaptations to viral tolerance and disease resistance www.nature.com/articles/s41... @hillermich.bsky.social @virology.bsky.social @emmateeling.bsky.social
www.nature.com
January 29, 2025 at 4:31 PM
Finally online - Bat genomes illuminate adaptations to viral tolerance and disease resistance www.nature.com/articles/s41... @hillermich.bsky.social @virology.bsky.social @emmateeling.bsky.social
Happy to report that our work on immune system adaptations in bats is now out in @nature.com 🦇🧬 www.nature.com/articles/s41... @ariadnamorales.bsky.social @batresearch.bsky.social @virology.bsky.social @DGKontopoulos.ecoevo.social.ap.brid.gy @sgn.one @bat1kgenomes.bsky.social Read more ...
Bat genomes illuminate adaptations to viral tolerance and disease resistance - Nature
A systematic analysis of 115 mammalian genomes, including 10 new bat genomes, reveals prevalent positive selection in immune genes in bats and shows key adaptations in the antiviral gene ISG15 that ai...
www.nature.com
January 29, 2025 at 4:25 PM
Happy to report that our work on immune system adaptations in bats is now out in @nature.com 🦇🧬 www.nature.com/articles/s41... @ariadnamorales.bsky.social @batresearch.bsky.social @virology.bsky.social @DGKontopoulos.ecoevo.social.ap.brid.gy @sgn.one @bat1kgenomes.bsky.social Read more ...