Jess Jana
@hi-its-jess.bsky.social
Immunology PhD Candidate @Pitt_PMI in @OveracreLab
shaped by @DelgoffeLab, @NagrathSunitha Lab, @UmichChemE
Cancer TME🤝Microbiome, T cells, Metabolism
she/her
shaped by @DelgoffeLab, @NagrathSunitha Lab, @UmichChemE
Cancer TME🤝Microbiome, T cells, Metabolism
she/her
Reposted by Jess Jana
I'm delighted to share a new story from our lab published today at @cp-cellmetabolism.bsky.social! In it, we describe how cellular therapies for cancer can be metabolically and epigenetically enhanced by redirecting how glucose is utilized during in vitro expansion. 1/ www.cell.com/cell-metabol...
Redirecting glucose flux during in vitro expansion generates epigenetically and metabolically superior T cells for cancer immunotherapy
T cell therapies for cancer currently rely on extensive in vitro expansion in hypermetabolic
conditions. Frisch et al. demonstrate that T cells grown in vitro perform extensive
aerobic glycolysis. Rer...
www.cell.com
January 28, 2025 at 6:34 PM
I'm delighted to share a new story from our lab published today at @cp-cellmetabolism.bsky.social! In it, we describe how cellular therapies for cancer can be metabolically and epigenetically enhanced by redirecting how glucose is utilized during in vitro expansion. 1/ www.cell.com/cell-metabol...