Torben Heick Jensen
@heick.bsky.social
RNA decay, RNA sorting, gene expression
Reposted by Torben Heick Jensen
How are RNAs sorted for export vs. degradation in the nucleus? In collaboration with @heick.bsky.social’s lab we (@clemensplaschka.bsky.social and @juliusbrennecke.bsky.social labs) discovered a direct mechanistic link between the export and decay machineries: www.biorxiv.org/content/10.1... (1/x)
Molecular basis of polyadenylated RNA fate determination in the nucleus
Eukaryotic genomes generate a plethora of polyadenylated (pA+) RNAs[1][1],[2][2], that are packaged into ribonucleoprotein particles (RNPs). To ensure faithful gene expression, functional pA+ RNPs, in...
www.biorxiv.org
September 22, 2025 at 11:23 PM
How are RNAs sorted for export vs. degradation in the nucleus? In collaboration with @heick.bsky.social’s lab we (@clemensplaschka.bsky.social and @juliusbrennecke.bsky.social labs) discovered a direct mechanistic link between the export and decay machineries: www.biorxiv.org/content/10.1... (1/x)
Reposted by Torben Heick Jensen
Dream collaboration with the groups of Torben Heick Jensen (@heick.bsky.social; @au.dk) and Clemens Plaschka (@impvienna.bsky.social). Building in part on the incredible work from Ulrich Hohmann on human mRNA export.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A molecular switch orchestrates the nuclear export of human messenger RNA
The nuclear export of messenger RNA (mRNA) is a key step in eukaryotic gene expression ([Köhler and Hurt, 2007][1]). Despite recent insights into the packaging of newly transcribed mRNAs into ribonucl...
www.biorxiv.org
September 17, 2025 at 12:42 PM
Dream collaboration with the groups of Torben Heick Jensen (@heick.bsky.social; @au.dk) and Clemens Plaschka (@impvienna.bsky.social). Building in part on the incredible work from Ulrich Hohmann on human mRNA export.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Final call for postdoc positions in Aarhus, Denmark. Sorting of gene expression and beyond. Please get in touch for further information or apply using this link:
mbg.au.dk/en/news-and-...
mbg.au.dk/en/news-and-...
A postdoc position in the Torben Heick Jensen lab, Aarhus University, Denmark: Mammalian Nuclear RNA Production and Turnover Systems - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University
mbg.au.dk
August 5, 2025 at 8:06 AM
Final call for postdoc positions in Aarhus, Denmark. Sorting of gene expression and beyond. Please get in touch for further information or apply using this link:
mbg.au.dk/en/news-and-...
mbg.au.dk/en/news-and-...
Second call for postdoc positions in the lab. Please follow the link below to apply or get in touch for further information.
mbg.au.dk/aktuelt/ledi...
mbg.au.dk/aktuelt/ledi...
A postdoc position in the Torben Heick Jensen lab, Aarhus University, Denmark: Mammalian Nuclear RNA Production and Turnover Systems - Ledig stilling på Aarhus Universitet
Ledig stilling ved Institut for Molekylærbiologi og Genetik - RNA-biologi og -innovation, Aarhus Universitet
mbg.au.dk
July 18, 2025 at 9:28 AM
Second call for postdoc positions in the lab. Please follow the link below to apply or get in touch for further information.
mbg.au.dk/aktuelt/ledi...
mbg.au.dk/aktuelt/ledi...
Postdoc positions available in the Heick Jensen lab in sunny Aarhus. Sorting of good and bad RNAs in mammalian nuclei. Please get in touch for further information and/or use the following link to apply:
mbg.au.dk/en/news-and-...
mbg.au.dk/en/news-and-...
A postdoc position in the Torben Heick Jensen lab, Aarhus University, Denmark: Mammalian Nuclear RNA Production and Turnover Systems - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - RNA Biology and Innovation, Aarhus University
mbg.au.dk
June 27, 2025 at 6:03 AM
Postdoc positions available in the Heick Jensen lab in sunny Aarhus. Sorting of good and bad RNAs in mammalian nuclei. Please get in touch for further information and/or use the following link to apply:
mbg.au.dk/en/news-and-...
mbg.au.dk/en/news-and-...
Reposted by Torben Heick Jensen
Thrilled to see my work with @adelmanlab.bsky.social on INT/dsRNA highlighted by @willgarland.bsky.social and @heick.bsky.social ! Thanks for beautifully capturing how nuclear RNA guardians prevent cellular chaos. The ripple effects of transcriptional dysregulation are indeed profound! #RNABiology
We put together a spotlight for @cp-cellchembiol.bsky.social highlighting the recent work from @baluapuri.bsky.social and @adelmanlab.bsky.social published in @cp-cell.bsky.social.
Here they show how a breakdown in nuclear RNA regulation sends ripples of stress throughout the cell.
Here they show how a breakdown in nuclear RNA regulation sends ripples of stress throughout the cell.
June 19, 2025 at 7:47 PM
Thrilled to see my work with @adelmanlab.bsky.social on INT/dsRNA highlighted by @willgarland.bsky.social and @heick.bsky.social ! Thanks for beautifully capturing how nuclear RNA guardians prevent cellular chaos. The ripple effects of transcriptional dysregulation are indeed profound! #RNABiology
Reposted by Torben Heick Jensen
📣 🥳 🧑💻 Our department is hiring:
Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark
Deadline June 1st
Thanks for sharing!
mbg.au.dk/en/news-and-...
Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark
Deadline June 1st
Thanks for sharing!
mbg.au.dk/en/news-and-...
Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark - Vacancy at Aarhus University
Vacancy at Department of Molecular Biology and Genetics - BiRC - Bioinformatics Research Center, Aarhus University
mbg.au.dk
May 16, 2025 at 12:35 PM
📣 🥳 🧑💻 Our department is hiring:
Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark
Deadline June 1st
Thanks for sharing!
mbg.au.dk/en/news-and-...
Tenure-Track Assistant Professor / Associate Professor in Bioinformatics at Aarhus University, Denmark
Deadline June 1st
Thanks for sharing!
mbg.au.dk/en/news-and-...
Second call for a postdoc position in my lab. Please read more and apply here: mbg.au.dk/aktuelt/ledi...
Postdoc positions in Nuclear RNA Biology - Ledig stilling på Aarhus Universitet
Ledig stilling ved Institut for Molekylærbiologi og Genetik - RNA-biologi og -innovation, Aarhus Universitet
mbg.au.dk
March 4, 2025 at 3:23 PM
Second call for a postdoc position in my lab. Please read more and apply here: mbg.au.dk/aktuelt/ledi...
PhD position vacant in the lab. Please spread the news. Study topic: Mammalian nuclear RNA production and turnover systems. Learn more about the lab here: www.mRNP.au.dk
February 20, 2025 at 9:53 AM
PhD position vacant in the lab. Please spread the news. Study topic: Mammalian nuclear RNA production and turnover systems. Learn more about the lab here: www.mRNP.au.dk
Postdoc positions on nuclear RNA biology available in the Heick Jensen lab. Come join us in tiny Denmark. Interested? - then follow this link: mbg.au.dk/aktuelt/ledi...
Postdoc positions in Nuclear RNA Biology - Ledig stilling på Aarhus Universitet
Ledig stilling ved Institut for Molekylærbiologi og Genetik - RNA-biologi og -innovation, Aarhus Universitet
mbg.au.dk
February 12, 2025 at 9:02 AM
Postdoc positions on nuclear RNA biology available in the Heick Jensen lab. Come join us in tiny Denmark. Interested? - then follow this link: mbg.au.dk/aktuelt/ledi...
Reposted by Torben Heick Jensen
First paper of our lab today @natureportfolio.bsky.social by Nussi!
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
December 4, 2024 at 8:53 PM
First paper of our lab today @natureportfolio.bsky.social by Nussi!
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
We provide a real-time movie on how #transcription and #translation cooperate using #single-molecule FM: we find long-range #ribosome/ RNAP communication mediated by #RNA looping!
@embl.org #RNAbiology #RNASky
t.co/a24Xxcxdo0
Reposted by Torben Heick Jensen
I’m thrilled to share a collaborative story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu. We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Specific tRNAs promote mRNA decay by recruiting the CCR4-NOT complex to translating ribosomes
The CCR4-NOT complex is a major regulator of eukaryotic messenger RNA (mRNA) stability. Slow decoding during translation promotes association of CCR4-NOT with ribosomes, accelerating mRNA degradation....
www.science.org
November 22, 2024 at 6:09 PM
I’m thrilled to share a collaborative story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu. We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation!
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Torben Heick Jensen
November 21, 2024 at 8:17 PM
Reposted by Torben Heick Jensen
Exciting highlights of the recent complex life of #RNA symposium @embl.org featuring Matt Disney, Juan Valcarcel, @lapassmore.bsky.social, Herve Le Hir, Andreas Meyer, Yiliang Ding, Seitz Herve, Maria Hondele, @juliusbrennecke.bsky.social, Bahareh Torkzaban
www.embl.org/news/science...
www.embl.org/news/science...
November 21, 2024 at 2:12 PM
Exciting highlights of the recent complex life of #RNA symposium @embl.org featuring Matt Disney, Juan Valcarcel, @lapassmore.bsky.social, Herve Le Hir, Andreas Meyer, Yiliang Ding, Seitz Herve, Maria Hondele, @juliusbrennecke.bsky.social, Bahareh Torkzaban
www.embl.org/news/science...
www.embl.org/news/science...
Reposted by Torben Heick Jensen
November 13, 2024 at 6:16 PM
And RNA for that matter
Are there any "Bluesky transcription starter packs"?
November 17, 2024 at 10:32 AM
And RNA for that matter
Reposted by Torben Heick Jensen
Are there any "Bluesky transcription starter packs"?
November 17, 2024 at 9:56 AM
Are there any "Bluesky transcription starter packs"?