Haselbach Lab
@haselbachlab.bsky.social
cryo EM enthusiasts with interest in molecular machines.
A single tyrosine phosphorylation leads to dissociation from RPN11 and the ATPase making room for ubiquitinated substrates (4/6)
December 6, 2024 at 9:17 AM
A single tyrosine phosphorylation leads to dissociation from RPN11 and the ATPase making room for ubiquitinated substrates (4/6)
Structural characterization using cryoEM reveals how AKIRIN2 bridges interactions of the proteasome with the importin IPO9. This mechanism enables the mutual recruitment of importins and additional AKIRIN2 protomers, assembling a supramolecular complex. (3/7)
December 5, 2024 at 8:11 PM
Structural characterization using cryoEM reveals how AKIRIN2 bridges interactions of the proteasome with the importin IPO9. This mechanism enables the mutual recruitment of importins and additional AKIRIN2 protomers, assembling a supramolecular complex. (3/7)