Hamilton Lab @ VCU
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hamilton-lab.bsky.social
Hamilton Lab @ VCU
@hamilton-lab.bsky.social
Using synthetic biology to reveal how the brain adapts to drug use and stress experience.

https://hamilton-lab.weebly.com/
Reposted by Hamilton Lab @ VCU
My dissertation paper finally dropped in Nature Communications!

Overall, the conclusion is that psilocybin may be useful in reducing drug craving that often precipitates relapse through mechanisms related to 5-HT2A activation.

www.nature.com/articles/s41...
Sex-specific role of the 5-HT2A receptor in psilocybin-induced extinction of opioid reward - Nature Communications
Here Jaster et al., show a single psilocybin dose produce sex-specific post-acute changes in opioid reward and withdrawal via 5-HT2A receptors in frontal cortex-to–nucleus accumbens circuits, with epi...
www.nature.com
November 20, 2025 at 1:46 PM
Reposted by Hamilton Lab @ VCU
The Gowrishankar lab will be opening its doors @neuro_MUSC on Dec 1, 2025! We will be hiring at all levels. I will also be at @SfNtweets presenting my lab's vision on Wednesday, Nov 19, 8AM-12PM at poster board GG7. If you're interested, please reach out!

www.raajgowrishankarlab.org
Gowrishankar Lab
www.raajgowrishankarlab.org
November 12, 2025 at 10:23 PM
In a new paper, we analyze published RNAseq and discover impact to the expression of transposable element transcripts in the brains of people with major depressive disorder. Natalie Truby, a recent-grad from the lab, spearheaded this work.

Read about it here:
doi.org/10.1016/j.ja...
Redirecting
doi.org
September 5, 2025 at 5:44 PM
In this preprint, grad students Kijoon Kim and Corinne Smith re-programmed the function of the KZFP-interacting protein TRIM28. We discover that TRIM28 disfunction in mouse PFC releases TEs and impedes complex social behaviors. The work is an ode to community. Read about it below!
Derepression of transposable elements in mouse prefrontal cortex disrupts social behavior https://www.biorxiv.org/content/10.1101/2025.03.31.646358v1
April 4, 2025 at 2:09 PM
Reposted by Hamilton Lab @ VCU
A HUGE CONGRATULATIONS to @ericjnestler.bsky.social on being named Interim Dean of the Icahn School of Medicine! As we express great enthusiasm for Dr. Nestler becoming Dean & the exciting time ahead, please join us in thanking Dean Charney for his extraordinary service & commitment to Mount Sinai.
March 25, 2025 at 9:21 PM
Reposted by Hamilton Lab @ VCU
Pls share AMAZING opportunities! Studying Depression? its biology? UCI’s new Depression Res Ctr is hiring 1) Preclinical Models: systems mechanisms of vulnerability, resilience 2) Child Adolescent, Adult Depression 3) Biomed Engineer Deep Phenotype, Intervention recruit.ap.uci.edu/JPF09510 508, 507
Open-Rank Faculty Cluster Hire in Depression Research
University of California, Irvine is hiring. Apply now!
recruit.ap.uci.edu
March 11, 2025 at 6:25 PM
Reposted by Hamilton Lab @ VCU
UAB Neurobiology is hiring up to 4 new tenure-track faculty as part of 3 new open-rank searches. Come join our vibrant, supportive, and growing neuroscience community!
uab.peopleadmin.com/postings/23916
uab.peopleadmin.com/postings/23944
uab.peopleadmin.com/postings/24010
Academic Joint Departments-Open Rank/Tenure-Neurobiology
The University of Alabama at Birmingham (UAB) Heersink School of Medicine invites applications for 4 open-rank faculty positions in the Department of Neurobiology. We are seeking candidates who apply ...
uab.peopleadmin.com
March 11, 2025 at 10:52 PM