Georgios Kafetzis
@gkafetzis.bsky.social
PhD Student@University of Sussex w/ Tom Baden
MSc Neuroscience@University of Tübingen w/ Thomas Euler
Interested in visual neuroscience, neural design, evolution.
MSc Neuroscience@University of Tübingen w/ Thomas Euler
Interested in visual neuroscience, neural design, evolution.
So the retina wasn’t built de novo.
Instead, it is likely rooted in an ancestrally median, already complex eye — lateralized & rewired to solve early chordate sensory challenges.
More here:
www.biorxiv.org/content/10.1...
and curious what you think!
8/8
Instead, it is likely rooted in an ancestrally median, already complex eye — lateralized & rewired to solve early chordate sensory challenges.
More here:
www.biorxiv.org/content/10.1...
and curious what you think!
8/8
September 12, 2025 at 12:58 PM
So the retina wasn’t built de novo.
Instead, it is likely rooted in an ancestrally median, already complex eye — lateralized & rewired to solve early chordate sensory challenges.
More here:
www.biorxiv.org/content/10.1...
and curious what you think!
8/8
Instead, it is likely rooted in an ancestrally median, already complex eye — lateralized & rewired to solve early chordate sensory challenges.
More here:
www.biorxiv.org/content/10.1...
and curious what you think!
8/8
..with a huge payoff, in gradual steps:
✅Choice of right depth
✅Body Posture
✅Visually - guided locomotion, eventually
7/n
✅Choice of right depth
✅Body Posture
✅Visually - guided locomotion, eventually
7/n
September 12, 2025 at 12:58 PM
..with a huge payoff, in gradual steps:
✅Choice of right depth
✅Body Posture
✅Visually - guided locomotion, eventually
7/n
✅Choice of right depth
✅Body Posture
✅Visually - guided locomotion, eventually
7/n
But what if the sequence is backwards?
We argue that
bipolar cells were there 𝑒𝑎𝑟𝑙𝑦 — integral parts of parallel
microcircuits in a median eye.
And strikingly,
already in two flavors: 𝐎𝐅𝐅 and 𝐑𝐨𝐝-𝐎𝐍!
4/n
We argue that
bipolar cells were there 𝑒𝑎𝑟𝑙𝑦 — integral parts of parallel
microcircuits in a median eye.
And strikingly,
already in two flavors: 𝐎𝐅𝐅 and 𝐑𝐨𝐝-𝐎𝐍!
4/n
September 12, 2025 at 12:58 PM
But what if the sequence is backwards?
We argue that
bipolar cells were there 𝑒𝑎𝑟𝑙𝑦 — integral parts of parallel
microcircuits in a median eye.
And strikingly,
already in two flavors: 𝐎𝐅𝐅 and 𝐑𝐨𝐝-𝐎𝐍!
4/n
We argue that
bipolar cells were there 𝑒𝑎𝑟𝑙𝑦 — integral parts of parallel
microcircuits in a median eye.
And strikingly,
already in two flavors: 𝐎𝐅𝐅 and 𝐑𝐨𝐝-𝐎𝐍!
4/n
Most bilaterians keep photoreceptor types separate.
But vertebrate eyes are a mash-up:
🪡Ciliary (rods & cones) and
💈Rhabdomeric (ganglion, amacrine, horizontal)
…all packed into a multilayered circuit.
2/n
But vertebrate eyes are a mash-up:
🪡Ciliary (rods & cones) and
💈Rhabdomeric (ganglion, amacrine, horizontal)
…all packed into a multilayered circuit.
2/n
September 12, 2025 at 12:58 PM
Most bilaterians keep photoreceptor types separate.
But vertebrate eyes are a mash-up:
🪡Ciliary (rods & cones) and
💈Rhabdomeric (ganglion, amacrine, horizontal)
…all packed into a multilayered circuit.
2/n
But vertebrate eyes are a mash-up:
🪡Ciliary (rods & cones) and
💈Rhabdomeric (ganglion, amacrine, horizontal)
…all packed into a multilayered circuit.
2/n