Thank you 🙏

Thank you 🙏

Thank you 🙏

This work was funded by BCCologne, SFB1530, SFB1399 and the CANTAR network and supported by the SFB_1403

A special thanks to Henning Walczak for all his support.
Thanks also to all other collaborators: Trifunovic lab, Federica Locci, Martin Peifer , Fabrizio De Bendetti, Giusi Prencipe and Antonella Insalaco.

Our work shows that STING triggers ZBP1-mediated necroptosis independently of TNFR1 and FADD. Inhibiting necroptosis prevents STING-associated vasculopathy with onset in infancy (SAVI), paving the way for cell death inhibition as a therapeutic strategy for STING-driven inflammatory diseases