jhayne
@foxtongue.bsky.social
dilettante, bon vivant. currently based in toronto.
early net adopter, writing/security/art/culture/tech, twice legally dead yet somehow still here.
:: www.foxtongue.com
:: www.instagram.com/foxtongue
:: founding member of www.somanyofus.com
early net adopter, writing/security/art/culture/tech, twice legally dead yet somehow still here.
:: www.foxtongue.com
:: www.instagram.com/foxtongue
:: founding member of www.somanyofus.com
Reposted by jhayne
It's also interesting to note how this is entirely normal, it's why such as curing cancer is very difficult: that gene you're looking at almost certainly does dozens or hundreds of completely different very essential things, it's load-bearing.
October 17, 2023 at 5:53 AM
It's also interesting to note how this is entirely normal, it's why such as curing cancer is very difficult: that gene you're looking at almost certainly does dozens or hundreds of completely different very essential things, it's load-bearing.
Reposted by jhayne
It's interesting to think that when you get covid, which reactivates the EBV you almost certainly have (90% of all adults in the US have EBV), *that* reactivates a chunk of a 25 million year old retrovirus that's been hanging out in your genes.
October 17, 2023 at 5:52 AM
It's interesting to think that when you get covid, which reactivates the EBV you almost certainly have (90% of all adults in the US have EBV), *that* reactivates a chunk of a 25 million year old retrovirus that's been hanging out in your genes.
Reposted by jhayne
70% of MS diagnoses are in cis women, and a large part of that is because high estrogen makes it easier for ERVW-1 to be expressed by EBV.
October 17, 2023 at 5:52 AM
70% of MS diagnoses are in cis women, and a large part of that is because high estrogen makes it easier for ERVW-1 to be expressed by EBV.
Reposted by jhayne
That little chunk of a retrovirus that infected one of your primate ancestors 25 million years ago, is still in your genome, and when it works normally it helps you give birth.
When it fucks up, it gives you multiple sclerosis
When it fucks up, it gives you multiple sclerosis
October 17, 2023 at 5:51 AM
That little chunk of a retrovirus that infected one of your primate ancestors 25 million years ago, is still in your genome, and when it works normally it helps you give birth.
When it fucks up, it gives you multiple sclerosis
When it fucks up, it gives you multiple sclerosis
Reposted by jhayne
ERVW-1, when expressed at the wrong time in the wrong cells, causes multiple sclerosis.
The Epstein-Barr virus, human herpesvirus 4, turns on ERVW-1. This is how it causes MS.
The Epstein-Barr virus, human herpesvirus 4, turns on ERVW-1. This is how it causes MS.
October 17, 2023 at 5:51 AM
ERVW-1, when expressed at the wrong time in the wrong cells, causes multiple sclerosis.
The Epstein-Barr virus, human herpesvirus 4, turns on ERVW-1. This is how it causes MS.
The Epstein-Barr virus, human herpesvirus 4, turns on ERVW-1. This is how it causes MS.
Reposted by jhayne
That gene is ERVW-1, endogenous retrovirus group W.
Once, 25 million years ago, it helped that retrovirus evade a primate's immune system.
Now you use it so your immune system doesn't kill your embryo.
Once, 25 million years ago, it helped that retrovirus evade a primate's immune system.
Now you use it so your immune system doesn't kill your embryo.
October 17, 2023 at 5:50 AM
That gene is ERVW-1, endogenous retrovirus group W.
Once, 25 million years ago, it helped that retrovirus evade a primate's immune system.
Now you use it so your immune system doesn't kill your embryo.
Once, 25 million years ago, it helped that retrovirus evade a primate's immune system.
Now you use it so your immune system doesn't kill your embryo.
Reposted by jhayne
That retrovirus dumped its genes into chromosome 7. It's still there, in your genome right now.
Almost all of it's been rendered nonsense and doesn't code for anything. But it can still make Syncytin-1 for you
Almost all of it's been rendered nonsense and doesn't code for anything. But it can still make Syncytin-1 for you
October 17, 2023 at 5:50 AM
That retrovirus dumped its genes into chromosome 7. It's still there, in your genome right now.
Almost all of it's been rendered nonsense and doesn't code for anything. But it can still make Syncytin-1 for you
Almost all of it's been rendered nonsense and doesn't code for anything. But it can still make Syncytin-1 for you
Reposted by jhayne
But it was very clearly _not_ a protest. It doesn’t build power in the way that only antagonistic, confrontational protest can. We were in the Village, alongside folks in ACT UP “Silence = Death” shirts, so I got to explain what *real* protest is, in an American context, and that it has risks.
October 21, 2025 at 5:17 AM
But it was very clearly _not_ a protest. It doesn’t build power in the way that only antagonistic, confrontational protest can. We were in the Village, alongside folks in ACT UP “Silence = Death” shirts, so I got to explain what *real* protest is, in an American context, and that it has risks.
Reposted by jhayne
The NK march, by the most positive lens, was a demonstration expanding reach, shifting the Overton window, building confidence for those who are less committed or fluent in the context & issues. More simply, it’s a great on-ramp for normies, and delivers respectability for institutions that need it.
October 21, 2025 at 5:17 AM
The NK march, by the most positive lens, was a demonstration expanding reach, shifting the Overton window, building confidence for those who are less committed or fluent in the context & issues. More simply, it’s a great on-ramp for normies, and delivers respectability for institutions that need it.