fourthdose.bsky.social
@fourthdose.bsky.social
Reposted
That's not surprising because some senescent cells have beneficial functions (e.g. anti-cancer) and there's no easy way to target the bad ones
www.sciencedirect.com/science/arti...
July 6, 2025 at 6:41 PM
Reposted
What's the optimal number of steps of physical activity this is associated with multiple (9) favorable outcomes?
The largest, systematic review of 57 studies, 35 cohorts.
7,000 steps is clinically meaningful, benefit also seen for 4,000 steps cf 2,000 steps
thelancet.com/journals/lan...
Daily steps and health outcomes in adults: a systematic review and dose-response meta-analysis
Although 10 000 steps per day can still be a viable target for those who are more active, 7000 steps per day is associated with clinically meaningful improvements in health outcomes and might be a mor...
thelancet.com
July 23, 2025 at 10:34 PM
n=35, kidney #transplant recipients.
Protokolla "vähennä #siklosporiini annosta 80% #Paxlovid kuurin ajaksi" on hyvä, paitsi heti Paxlovid-kuurin jälkeen mittaa siklosporiini, eikä 2 päivää kuurin jälkeen.
Mittaa 2 pv välein, kunnes normaali.
Max 4 lisäpäivää -80%.
journals.lww.com/kidney360/ab...
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August 3, 2025 at 6:20 PM
Reposted
Here are the influenza cases for Australia, by year since 2010. 2025 will be the 4th huge year in a row - wildly unprecedented.

It's increasingly hard to not draw the conclusion that something broke from 2022 onwards. Immune systems?
1/
July 22, 2025 at 11:38 AM
Reposted
Australian COVID-19 weekly stats update:

The risk estimate fell again to 0.6% “Currently Infectious”, or 1-in-170.

That implies a 16% chance that someone is infectious in a group of 30.

#COVID19 #Australia
🧵
August 2, 2025 at 10:13 PM
Reposted
Australian Influenza cases update:

Reported Influenza cases for Australia have peaked in late July, at a slightly lower level than the 2024 wave.

#Influenza #Australia
🧵
August 3, 2025 at 9:42 AM
Reposted
Australian COVID-19 weekly stats update:

The risk estimate fell again slightly to 0.7% “Currently Infectious”, or 1-in-142. The rate of descent appears to be slowing, far above the usual baseline.

That implies a 19% chance that someone is infectious in a group of 30.

#COVID19 #Australia
🧵
July 26, 2025 at 10:04 PM