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fmontecinos84.bsky.social
@fmontecinos84.bsky.social
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fmontecinos84.bsky.social @fmontecinos84.bsky.social · Jan 3
The cryoEM structure of blood cell-specific tubulin is out! @cryoempapers.bsky.social @pdbeurope.bsky.social @actacrystd.iucr.org

www.sciencedirect.com/science/arti...
Structure of blood cell-specific tubulin and demonstration of dimer spacing compaction in a single protofilament
Microtubule (MT) function plasticity originates from its composition of α− and β−tubulin isotypes and the post-translational modifications of both sub…
www.sciencedirect.com
Reposted
embojournal.org
Issue 21 highlights:
Paxilin’s nuclear switch in the brain
RING E3s reading & extending ADPr-ubiquitin
Review: Decoding immunometabolism
Nuclear actin limits chromatin leakage upon migratory squeeze
Cover by @syncellbiolab.bsky.social: unlike Odin-archael FtsZ twins
www.embopress.org/toc/14602075...
November 3, 2025 at 11:23 AM
Reposted
thelancetinfdis.bsky.social
Read our November issue!

Featuring testing olorofim to treat fungal infections, introduction of nirsevimab for RSV in Chile, and new oxazolidinones for tuberculosis therapy.

www.thelancet.com/issue/S1473-...
October 23, 2025 at 8:55 AM
Reposted
cristinabellino.bsky.social
Roberto Matta, "The Bachelors Twenty Years Later", 1943
Philadelphia Museum of Art

Roberto Matta on La Mariée Mise à Nu par ses Célibataires, même: "Painting - glass - mirror - these are the three substances in the dynamic interrelation to the final image of the Glass...
1/2
July 16, 2024 at 7:48 AM
Reposted
mkaloumenos.bsky.social
Daily Piece of Art

🎨 Roberto Matta 🇨🇱 (1911 - 2002)
🖼️ On the Edge of a Dream (1956) - oil on canvas
#art #painting #surrealism
January 14, 2025 at 12:15 PM
Reposted
pablopicasso.bsky.social
The Pike (La Pique)
https://botfrens.com/collections/111/contents/1156260
Gift of Mr. and Mrs. Armand P. Bartos
October 25, 2025 at 5:24 PM
Reposted
jcb.org
Perspective from Richard McIntosh describing the history of research on #microtubule polymerization in terms of the ideas, technologies, and observations that have emerged as countless researchers have studied the dynamics of these essential cytoskeletal polymers. rupress.org/jcb/article/...
October 15, 2025 at 4:02 PM
Reposted
guggenheim.bsky.social
Levels by Vasily Kandinsky, 1929
https://botfrens.com/collections/212/contents/137781
Solomon R. Guggenheim Museum, New York Solomon R. Guggenheim Founding Collection © 2016 Artists Rights Society (ARS), New York/ADAGP, Paris
October 11, 2025 at 3:34 AM
Reposted
bpodaily.bsky.social
Previously unknown contacts between mitochondria identified using new approach with AI & volumetric electron microscopy

📹 Benjamin S. Padman, Runa S.J. Lindblom & @lazaroulab.bsky.social, @monashuniversity.bsky.social @jcb.org

➡️ bpod.org.uk/archive/2025/10/3 with
@antdlewis.bsky.social
October 4, 2025 at 4:20 PM
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guggenheim.bsky.social
Years of Fear by Matta, 1941 #artbots #guggenheim
https://botfrens.com/collections/212/contents/137917
Solomon R. Guggenheim Museum, New York © 2016 Artists Rights Society (ARS), New York/ADAGP, Paris
August 20, 2025 at 6:07 PM
Reposted
drianweissman.bsky.social
Nike co-founder Phil Knight and his wife Penny Knight have pledged to donate $2 billion to Oregon Health & Science University’s Knight Cancer Institute, the school announced Thursday, describing it as the largest single gift to a U.S. university.
apnews.com/article/ohsu...
Nike co-founder Phil Knight and wife pledge record $2B to Oregon cancer center, university says
An Oregon university says Nike co-founder Phil Knight and his wife Penny Knight have pledged a record $2 billion to its cancer center.
apnews.com
August 15, 2025 at 2:44 AM
Reposted
hoxinsocks.bsky.social
#TubulinTuesday!
j-today.bsky.social Joey Tidei @j-today.bsky.social · Aug 1
Microtubules 🟢 protruding into the dynamic actin 🟣 network of a neuronal growth cone in DIV2 hippocampal neurons. @spirochrome.com SiR-Tubulin and SPY-FastActX working wonders on this #FluorescenceFriday
August 5, 2025 at 2:50 PM
Reposted
wonderofscience.bsky.social
A stars massive outburst captured by the Hubble Space Telescope.

Credit: NASA/ESA
July 12, 2025 at 12:43 AM
Reposted
melaniemcdowell.bsky.social
Proud to share our first lab pre-print: “SND3 is the membrane insertase within a fungal multipass translocon” where @tzujingyang.bsky.social solved the structure of a ribosome-associated SND3-translocon complex involved in ER membrane protein insertion ➡️ doi.org/10.1101/2025...
July 12, 2025 at 12:49 AM
Reposted
sciencex.bsky.social
Natural compounds from turmeric and rhubarb have demonstrated potential to inhibit multidrug-resistant bacteria in wastewater, suggesting a possible strategy to address antibiotic resistance.
Chemicals from turmeric and rhubarb could help fight antibiotic-resistant bacteria lurking in wastewater
When people take antibiotics, some of the dose is excreted with urine and feces and ends up in our wastewater. The presence of this low dose of antibiotic creates an opportunity for resistant bacteria to evolve.
phys.org
July 10, 2025 at 4:02 AM
Reposted
cbsnews.com
Critically endangered leopard caught on camera in Bangladesh forest: "Extremely rare and secretive species" cbsn.ws/4esfOX1
Critically endangered leopard caught on camera in Bangladesh forest: "Extremely rare and secretive species"
The predator was once widely seen in forested areas. Habitat loss, lack of prey and poaching are key contributors to the loss of leopards, experts say.
cbsn.ws
June 30, 2025 at 2:00 AM
Reposted
plosbiology.org
#Glycoprotein 2 (GP2) filaments protect against infections by acting as decoys for the bacterial #lectin FimH. The #cryoEM structure of GP2 filaments provides insights into filament assembly and #antibacterial function in the digestive tract @plosbiology.org 🧪 plos.io/3HP2obF
Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.
June 24, 2025 at 4:22 PM
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guggenheim.bsky.social
Blue Painting by Vasily Kandinsky, 1924 #artbots #guggenheim
https://botfrens.com/collections/212/contents/137152
Solomon R. Guggenheim Museum, New York Gift, Fuller Foundation, Inc., 1976 © 2016 Artists Rights Society (ARS), New York/ADAGP, Paris
June 16, 2025 at 2:42 AM
Reposted
sagan.bsky.social
Isaac Asimov on, "If God is Dead, Everything is Permitted?"
June 11, 2025 at 1:59 PM
Reposted
autismadvocate.co.uk
“Dog chases down ambulance that owner is being transported in. When EMS realise, they let the dog in.”

Love this 🥰❤️

#DogSky
#Reddit
r\NextF***ingLevel
June 11, 2025 at 4:09 PM
fmontecinos84.bsky.social
Tubulin rings induced by cryptophycin show compacted longitudinal interfaces #TubulinTuesday
June 10, 2025 at 11:38 PM
Reposted
oliver48.bsky.social
"This was an experiment by a kindergarten class. They dropped seeds in the cracks of the sidewalk to see what would happen.
This would help our bees "
via I Love Bees
June 7, 2025 at 8:42 AM
Reposted
plosbiology.org
What are the molecular targets of inhaled anesthetics, such as isoflurane? Hideaki Ueda &co @riken-bdr.bsky.social @utokyoofficial.bsky.social report that isoflurane binds type 1 ryanodine receptor, which can be targeted to modulate sensitivity to #anesthesia. 🧪
plos.io/45EsVlx
Isoflurane activates the type 1 ryanodine receptor to induce anesthesia in mice
What are the molecular targets of inhaled anesthetics, such as isoflurane? This study reports that isoflurane binds type 1 ryanodine receptor, and determines that genetically disrupting a specific res...
plos.io
June 4, 2025 at 4:46 PM
Reposted
cryoempapers.bsky.social
Cryogenic light microscopy of vitrified samples with Angstrom precision www.biorxiv.org/content/10.1101/2025.05.27.656160v1 #cryoem
May 28, 2025 at 12:35 PM
Reposted
cryoempapers.bsky.social
Structure of blood cell-specific tubulin and demonstration of dimer spacing compaction in a single protofilament pubmed.ncbi.nlm.nih.gov/39725029/
December 27, 2024 at 4:48 PM