Erik Poppleton
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floppleton.bsky.social
Erik Poppleton
@floppleton.bsky.social
Postdoc working on RNA Nanotech & MD simulations @uniheidelberg.bsky.social & MPIP. GROMACS wrangler, oxDNA developer, @molpigs.bsky.social podcast host, and all around weird lil guy.

Has been known to post about music and neat bugs found in the woods.
Remember to twist your head to the right! I hear that’s good for range.
November 8, 2025 at 12:34 AM
Do you know if any of the results from this have ever been published? The video on the procedures was cool, but it didn’t actually explain much of what they saw in Will’s throat that surprised them so.
November 7, 2025 at 11:51 PM
(Obviously neither of these ended up being the case)
Also there weren’t as many high-cost “I Win” cards. You couldn’t just use Dream Halls to play Enter the Infinite and then goldfish your opponent.
November 4, 2025 at 9:28 PM
I love the concept of DIY feeds, but we need tools for (paid) feed building because everybody setting up their own hosting is expensive and difficult.

A lot of scientists came here, but they check it less than old Twitter.

Blocking is bad for individuals, but is overall healthy for the network.
November 3, 2025 at 10:35 PM
The last season had a lot of problems, which I largely attribute to compressed pacing and the showrunners knowing how to write characters, not worlds.

That being said, S8E2 was one of the best episodes of character-driven television I’ve ever seen.
November 2, 2025 at 12:39 PM
Tools:
The RNA helix was generated using oxView (oxview.org), a oxDNA viewer and structure editor.

QRNA (github.com/sunandanmukherjee/QRNAS) for relaxation, specifically of the backbones.

All-atom forcefield OL3 (kfc.upol.cz/ff_ol/index.php), currently the best out-of-the-box RNA forcefield.
oxView
oxview.org
October 28, 2025 at 10:21 AM
They can be re-purposed for research usage, they’re the same kind of GPUs used in things like weather prediction, drug design, and data analysis. But that requires the capital to buy up the hardware when the AI companies fall apart, which research institutes are currently struggling with.
October 8, 2025 at 4:10 PM
This really is part of the joy of science! I love hunting down papers from the early days of biochemistry or molecular biology and seeing the methods, the thought processes, and feeling the continuity with great names from the past.
October 2, 2025 at 9:54 AM
Oof, this is gnarly! Thanks for sharing.
September 29, 2025 at 9:49 PM
When you put it that way, I suppose what I’m asking for isn’t so different than what attention does with the tokens themselves.
September 26, 2025 at 10:05 PM
Has there been any research on ‘fuzzy’ tokenizers? The reason we can mentally combine ‘going to’ and ‘gonna’ is because of this map between words and sound which lets those co-exist, while ‘boing to’ would be different. Probably too much processing power in the tokenizer layer for that to work tho.
September 26, 2025 at 9:09 PM
Also, I added you to the Molecular Programming feed posting list. If you include a 🧬 emoji in your posts, they should get picked up by the feed:

bsky.app/profile/did:...
September 26, 2025 at 2:03 PM
This is great! Would love to see if this method could be used to get the stacking energies of the inverted A|A stack in the kissing loops used in RNA origami.
September 26, 2025 at 2:01 PM
Reposted by Erik Poppleton
Anyway, learning another language is good for you because you die a thousand deaths of embarrassment and then you come out more humble and even more aware of your various human failings
September 26, 2025 at 1:19 PM