Federico Lopez
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flopezos.bsky.social
Federico Lopez
@flopezos.bsky.social
Evolutionary biology, genomics, bioinformatics, social insects.
Reposted by Federico Lopez
My book 'The Tree of Life' is published in the USA and Canada today.

Available as book, on kindle and as audio.

I would be really grateful for reposts.

www.amazon.com/Tree-Life-So...
www.amazon.ca/Tree-Life-So...
November 11, 2025 at 12:01 PM
Reposted by Federico Lopez
Independently evolved supergenes control colony social organization and queen reproductive strategies in several ant lineages. Sigeman et al. uncover a novel 9 Mb supergene controlling queen size and social organization in Myrmica ruginodis.

🔗 doi.org/10.1093/molbev/msaf255

#evobio #molbio #ants
November 5, 2025 at 11:24 AM
Functional genetic elements of a butterfly mimicry supergene

www.pnas.org/doi/abs/10.1...
Functional genetic elements of a butterfly mimicry supergene | PNAS
Development requires the coordinated action of many genes across space and time, yet numerous species can develop discrete, alternate phenotypes. S...
www.pnas.org
November 4, 2025 at 2:29 PM
Reposted by Federico Lopez
Reposted by Federico Lopez
Wrote up a little intervention post/explanation for my class about why using LLMs for trying to learn programming (as first time learners!) is bad and detrimental datavizf25.classes.andrewheiss.com/news/2025-11...
November 2, 2025 at 10:17 PM
Reposted by Federico Lopez
Mosquito cell atlas is now published! Congratulations to @nadavshai.bsky.social and @oliviagoldman.net and the many other collaborators that contributed to this resource. www.cell.com/cell/fulltex...
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female Aedes aegypti mosquitoes reveals sexual dimorphism in sensory systems and brain cell types and widespread co-expres...
www.cell.com
October 30, 2025 at 3:18 PM
Reposted by Federico Lopez
What do the naked mole rat and bowhead whale (lives to ~200 years) have in common to explain their remarkable longevity?
Enhanced DNA repair
www.nature.com/articles/s41...
erictopol.substack.com/p/a-long-awa...
Evidence for improved DNA repair in long-lived bowhead whale - Nature
Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.  &nbs...
www.nature.com
October 29, 2025 at 4:26 PM
Reposted by Federico Lopez
Russia on Wednesday unleashed a broad attack that hit a kindergarten, power plants and other sites in Ukraine, killing six people. The barrage came hours after President Trump said he was putting off a planned meeting with President Vladimir Putin to avoid a “wasted” effort toward ending the war.
Russia Hits Kindergarten and Power Plants Hours After Trump Delays Summit
President Volodymyr Zelensky of Ukraine said the overnight assault showed that Russia “clearly doesn’t feel enough pressure to stop prolonging the war.”
nyti.ms
October 22, 2025 at 2:06 PM
Reposted by Federico Lopez
Russia attacked Ukraine overnight, killing at least six people and leaving parts of the country without power as temperatures drop.

More than 400 drones and 28 missiles were launched.
After Trump-Putin summit suspended, Russia pounds Ukraine, killing six
The apparent collapse of the latest summit and renewed Russian attacks show that Trump’s hopes for a negotiated solution to the war remain distant.
www.washingtonpost.com
October 22, 2025 at 2:06 PM
Reposted by Federico Lopez
🔴 BREAKING: President Zelenskyy shared images of a kindergarten in Kharkiv targeted in Russian attack earlier today.

One person was killed and seven others were injured in the attack on the city, mayor says.
October 22, 2025 at 9:31 AM
Reposted by Federico Lopez
Snow leopards have the lowest genetic diversity of all big cats due to persistently small population sizes throughout their evolutionary history, which may make recovery from human hunting and habitat loss challenging. In PNAS: https://ow.ly/HM3350XeeBY
October 17, 2025 at 7:00 PM
Reposted by Federico Lopez
Across scientific disciplines, US university departments are cutting the numbers of PhD candidates they plan to accept in the current application cycle, for students due to begin in 2026, according to a Nature news article. Some plan to pause admissions altogether. #Academicsky 🧪
US PhD admissions shrink as fears over Trump’s cuts take hold
Some doctoral programmes are admitting no students at all amid uncertainty about federal science funding.
go.nature.com
October 21, 2025 at 8:27 PM
Reposted by Federico Lopez
Excited to share our new #biorxivpreprint:
“Sexual dimorphism in the complete connectome of the Drosophila male central nervous system” www.biorxiv.org/content/10.1...

We describe the #connectomics reconstruction and analysis of an entire adult #maleCNS #drosophila central nervous system. 1/10
October 15, 2025 at 4:17 PM
Reposted by Federico Lopez
In 2021, Wellcome Open Research launched the Tree of Life Gateway with the goal to publish the genome sequences of every species.

In 2024, the Gateway published the 1,000th Genome Note.

Explore this milestone with our recent blog post 🔗spr.ly/6009AxyLP

@sangerinstitute.bsky.social
October 14, 2025 at 6:00 PM
Reposted by Federico Lopez
Read ‘Sperm sequencing reveals extensive positive selection in the male germline’ from @sangerinstitute.bsky.social and collaborators in @nature.com below:

nature.com/articles/s41...
Sperm sequencing reveals extensive positive selection in the male germline - Nature
A combination of whole-genome NanoSeq with deep whole-exome and targeted NanoSeq is used to accurately characterize mutation rates and genes under positive selection in sperm cells.
nature.com
October 8, 2025 at 3:36 PM
Reposted by Federico Lopez
Funny story, though, we found this gene in NCBI databases, but it was annotated in Streptococcus pneumoniae! This is surely human contamination in a bacterial strep sample that was not properly filtered. Lesson: use CHM13, or better yet a pangenome, when filtering for human contamination...
October 10, 2025 at 3:25 PM
Reposted by Federico Lopez
Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation
www.science.org/doi/10.1126/...
October 9, 2025 at 6:06 PM
Reposted by Federico Lopez
This:
www.nature.com/articles/d41...
Absolutely yes. And I'm proud that @asn-amnat.bsky.social has led the way on this with requiring code and data editors checking code for about five years now!
Stop treating code like an afterthought: record, share and value it
Scientists, research institutions, funders, libraries and publishers must all improve software practices.
www.nature.com
October 9, 2025 at 3:52 PM
Reposted by Federico Lopez
More than 20 species of birds produce convergent whining vocalizations towards their brood parasites. Model presentation and playback experiments across multiple continents suggest that these learned calls provoke an innate response even among allopatric species 🧪🐦

www.nature.com/articles/s41...
Learned use of an innate sound-meaning association in birds - Nature Ecology & Evolution
Over 20 species of geographically and phylogenetically diverse bird species produce convergent whining vocalizations towards their respective brood parasites. Model presentation and playback experiments across multiple continents suggest that these learned calls provoke an innate response even among allopatric species.
www.nature.com
October 7, 2025 at 7:59 AM
Reposted by Federico Lopez
🙏🇺🇦 Residential buildings, an industrial park, a humanitarian aid warehouse, civilian infrastructure. Peaceful residents of Lviv and Zaporizhzhia once again survived a night attack by Russian barbarians.
October 5, 2025 at 7:15 AM
Reposted by Federico Lopez
5,5h of the wild air attack against Lviv and the region in the west with drones, cruise missiles and ballistic. Locals reported explosions of the magnitude and intensity they've never heard before. A civilian industrial park is on fire.

I hate russia, the world's rotten hole.
October 5, 2025 at 6:10 AM