It takes two to TANGO2!

TANGO2 binds the heat shock protein crystallin alpha B to prevent aggregation of the intermediate filament desmin and its loss models TANGO2-deficiency disorder

Many thanks to our team, collaborators and reviewers

rdcu.be/epI3p

#metabolism
#mitochondria
#genetic disorders

Ready to make breakthroughs in gene editing and mitochondrial biology in sunny Western Australia? Join our vibrant team as a Research Associate or Research Fellow. Expertise in cryo-EM, cell imaging, or mammalian genetic screens is highly desirable
staff.curtin.edu.au/explore-care...

New structural and functional analyses show that FASTKD4 supports non-canonical RNA processing and MT-ND3 mRNA stability. Thanks to all authors for their contributions and the reviewers for their kind advice!

academic.oup.com/nar/article/...

#RNA
#mitochondria
#mtDNA