We explored how evolution shaped the structure–function relationship of the insulin receptor (IR) family using a simplified model — the fruit fly. 🪰
rdcu.be/eM7zG
We explored how evolution shaped the structure–function relationship of the insulin receptor (IR) family using a simplified model — the fruit fly. 🪰
rdcu.be/eM7zG
Using computational protein design, we developed de novo ligands that induce distinct active conformations of the insulin receptor (IR).
🔗 Read the paper: authors.elsevier.com/sd/article/S...
Using computational protein design, we developed de novo ligands that induce distinct active conformations of the insulin receptor (IR).
🔗 Read the paper: authors.elsevier.com/sd/article/S...