Esther Uijttewaal
@euijttewaal.bsky.social
My PhD work is published! 🌟 We developed CRISPR-StAR, a new genetic screening method that uses internal controls that face the same challenges as edited cells—making the results more robust. In therapy-resistant melanoma, we revealed differential genetic dependencies in vitro and in vivo. Curious?
CRISPR-StAR enables high-resolution genetic screening in complex in vivo models - Nature Biotechnology
Pooled genetic CRISPR screening is improved in complex models through leveraging internal controls.
www.nature.com
December 18, 2024 at 3:10 PM
My PhD work is published! 🌟 We developed CRISPR-StAR, a new genetic screening method that uses internal controls that face the same challenges as edited cells—making the results more robust. In therapy-resistant melanoma, we revealed differential genetic dependencies in vitro and in vivo. Curious?
Reposted by Esther Uijttewaal
Today we published a new paradigm to do CRISPR screens in complex model systems such as in vivo but also e.g. in organoids. The publication came out in Nature Biotechnology.
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www.nature.com/articles/s41...
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www.nature.com/articles/s41...
CRISPR-StAR enables high-resolution genetic screening in complex in vivo models - Nature Biotechnology
Pooled genetic CRISPR screening is improved in complex models through leveraging internal controls.
www.nature.com
December 16, 2024 at 12:02 PM
Today we published a new paradigm to do CRISPR screens in complex model systems such as in vivo but also e.g. in organoids. The publication came out in Nature Biotechnology.
1/
www.nature.com/articles/s41...
1/
www.nature.com/articles/s41...